Clinical trials: Heart Failure Patients
Heart Failure, Healthy Volunteer
Study to Evaluate the Safety and Tolerability of AMG 986 in Healthy Volunteers and Heart Failure Patients
To evaluate the safety and tolerability of ascending single (Part A) and ascending multiple (Part B) doses of AMG 986 in healthy adults and of ascending multiple oral doses of AMG 986 in heart failure patients (Part C).
- Trial name
- NCT03276728
- Testing
- AMG 986 IV, AMG 986 PO
- Where
- 25 sites in United States, Australia and 7 more
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Amgen
Heart Failure
A Study Evaluating Biomarkers in Participants With Heart Failure (MK-0000-344)
The aim of this 2-part study is to assess B-type natriuretic peptide (BNP) as well as other circulating and imaging biomarkers in myocardial function.
- Trial name
- NCT02364752
- Testing
- Blood Draw, Loop Diuretic Withdrawal/Salt Load
- Volunteers
- healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Acute Heart Failure, Diabetes Mellitus
Short Term Outcome of Acute Heart Failure in Diabetic and Non Diabetic Patients
Around 26 million people suffer from heart failure (HF) globally, and the prevalence is increasing with an increasing longevity, prevalence of risk factors, and improved survival in patients with cardiovascular diseases In Egypt…
- Trial name
- NCT06447467
- Testing
- pro BNP
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Left Ventricular Failure, Unspecified
Daily Life Activities in Patients Treated With Continuous-Flow Left Ventricular Assist Devices
Investigation of oxygen uptake during daily life activities in HF patients with and without LVADs.
- Trial name
- Act-VAD (NCT04732039)
- Testing
- Measurement of peak oxygen uptake
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Failure, Arrhythmias, Cardiac
Evaluation of ECG Transmission and AI Models Using Apple Watch ECGs and Symptoms Data Collected Using a Mayo iPhone App
The purpose of the study is to determine if the Electrocardiograms (ECGs) and symptoms data obtained from an Apple Watch and transmitted to Mayo Clinic are of sufficient quality to guide a person's care.
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Health Care Utilization
- Trial name
- NCT05324566
- Where
- United States
- Volunteers
- 4,163 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Failure, Congestive
A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure
Transient receptor potential vanilloid 4 (TRPV4) channel blockade may be promising in the treatment of pulmonary oedema and dyspnoea in heart failure (HF) and acute decompensated heart failure (ADHF) patients by re-establishing…
- Trial name
- NCT02135861
- Testing
- DCE-MRI scans, Gadobutrol
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Heart Failure, Cardiac Failure
Impact of the Aerobic Exercise Versus Exercise of Force on the Hemodynamic, Lipidic, Anthropometric and Psychological Variables of Patients With Cardiac Failure
Introduction and objectives: At the global level, cardiovascular diseases are the leading cause of mortality. Currently, rehabilitation programs are shown as an effective treatment to mitigate the effects of heart failure.
- Trial name
- NCT03913780
- Testing
- Aerobic exercise more force
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- University Tolteca
Depression, Stage B Heart Failure
The Light Heart Study: Daily Light Box Use for Depressive Symptoms in Patients With Stage B Heart Failure
The Light-Heart study is a randomized, double-blind, controlled trial investigating the effects of bright white light (BWL) therapy on depressive symptoms, quality of life, and functioning in patients with Stage B heart failure.
- Trial name
- Light-Heart (NCT02691000)
- Testing
- LiteBook
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Heart Failure，Congestive
Implementing a Digitally-enabled Community Health Worker Intervention for Patients With Heart Failure
The purpose of this study is to assess the acceptability, feasibility, and preliminary effectiveness of implementing a 30-day digitally-enabled community health worker intervention compared to usual care with a community health…
- Trial name
- NCT05130008
- Testing
- Digitally-enabled CHW Care, Usual CHW Care
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Heart Failure, Diffuse Fibrosis
Using Cardiovascular Magnetic Resonance Tissue Characterisation and Wearable Technology to PREDICT Clinical Outcomes, Response to Therapy and Arrhythmias in Hospitalised Heart Failure Patients
150 patients admitted to University Hospital Southampton with heart failure will undergo comprehensive Cardiovascular Magnetic Resonance (CMR) imagining during their admission and continuous heart rhythm monitoring using wearable…
- Conditions
- Heart Failure, Diffuse Fibrosis, Focal Fibrosis, Arrythmia
- Trial name
- PREDICT-HF (NCT03689426)
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Critical Illness, Chronic Obstructive Lung Disease
Advance Care Planning Evaluation in Hospitalized Elderly Patients
The purpose of the study is to inform decision-makers of the best strategies to implement advanced care planning (ACP). An advanced care plan (ACP) is a verbal or written instruction describing what kind of care an individual…
- Conditions
- Critical Illness, Chronic Obstructive Lung Disease, Congestive Heart Failure, Cirrhosis
- Trial name
- ACCEPT (NCT01362855)
- Where
- 9 sites in Canada
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- Daren K. Heyland
Heart Failure
The Effect of Video Training o Symptom Management With Heart Failure
The purpose of this clinical study is to compare the effect of video-assisted training on the quality of life and symptom management of patients over the age of 65.
- Trial name
- NCT06068725
- Testing
- Training videos
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Ege University