Clinical trials: Heart Health Screening and Prevention
Atrial Fibrillation
Effectiveness of Early Detection of Atrial Fibrillation
To verify if the screening opportunistic of Atrial Fibrillation (AF) by means of the measurement of the arterial peripheral pulse is more effective than the habitual practice for the early detection of AF in 65-year-old who come…
- Trial name
- FAMDAP (NCT01291953)
- Testing
- Screening, Control
- Volunteers
- 6,990 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Rheumatic Heart Disease
Screening and Secondary Prevention Rheumatic Heart Disease Study
After basic clinical screening including history and physical, Point of care ultrasound will be performed to look at Mitral, Aortic and Tricuspid Valves for regurgitation or stenosis.
- Trial name
- S2-RHD (NCT05991219)
- Where
- Pakistan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Diabetes Mellitus, Cardiovascular Diseases
Towards Optimal Screening and Management of Coronary Artery Disease in Diabetes: TOSCANA Study
There are currently only few data on the coronary artery calcium score in patient with diabetes in France, and the diagnostic and therapeutic attitudes towards a high coronary artery calcium score are not standardized and depend…
- Trial name
- TOSCANA (NCT05314140)
- Testing
- Coronary artery calcium score evaluation
- Where
- 9 sites in France
- Sponsor
- French Cardiology Society
Atherosclerosis, Atheroscleroses, Coronary
Detection of Coronary Artery Calcifications by Whole Blood Transcriptome Analyzed by Artificial InTelligence Algorithms
The goal of this observational study is to determine the diagnostic accuracy of peripheral whole blood transcriptomes analyzed by an artificial intelligence algorithm to detect the presence and extent of coronary calcification in…
- Conditions
- Atherosclerosis, Atheroscleroses, Coronary, Atherosclerotic Plaque
- Trial name
- CAC-TRAIT (NCT05619042)
- Where
- Argentina
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Santiago Gabriel Miriuka
Cardiovascular Diseases, Cardiovascular Risk Factor
Digital Nudges to Improve Heart Health Actions After Community Screening in Malaysia (NADI-MyHeartRisk)
This is a pragmatic, risk-stratified, individually randomized controlled trial testing whether personalised WhatsApp-based digital behavioural nudges can improve completion of cardiovascular preventive actions after community…
- Trial name
- NADI-MHR (NCT07879144)
- Testing
- Personalised Digital Behavioural Nudges (NADI-MyHeartRisk Enhanced Pathway)
- Where
- 2 sites in Malaysia
- Volunteers
- 6,588 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Advancement and Research Excellence Institute
Breast Cancer Risk, Cardiovascular Disease Risk
The RISC Registry--Risk Informed Screening Registry
Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States. Six in ten adults have one chronic disease; 4 in 10 have two or more.
- Conditions
- Breast Cancer Risk, Cardiovascular Disease Risk, Cardiometabolic Risk, Diabetes
- Trial name
- RISC (NCT05848856)
- Testing
- Breast Cancer, Cardiometabolic, Cardiovascular Risk Screening and Follow up
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Precision Health Equity Initiative
Rheumatic Heart Disease, Rheumatic Heart Disease in Children
Effectiveness of a School-centered Prevention Program on Prevalence of Latent Rheumatic Heart Disease
The overall objective is to evaluate the effectiveness of a school-centered primary and secondary prevention program on the prevalence of latent rheumatic heart disease among schoolchildren in Nepal, and to investigate the role…
- Trial name
- NEPAL4 (NCT05504928)
- Testing
- School nurse program
- Where
- Nepal
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiovascular Diseases, Hypertension
Uppsala Self-Screening of Cardiovascular Health
U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can…
- Conditions
- Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus
- Trial name
- U-SCREEN (NCT07614659)
- Testing
- Home-based multimodal cardiovascular screening
- Where
- Sweden
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Johan Sundström
Lipoprotein(a)
Heart CT Imaging to Detect Early Coronary Artery Disease in First-Degree Relatives With High or Low Lipoprotein(a) Identified Through Family Screening
Lipoprotein(a), or Lp(a), is a type of cholesterol that can increase the risk of heart and blood vessel disease. Many people are unaware they have high Lp(a), since it is not routinely measured and usually causes no symptoms on…
- Trial name
- IMAGE-LPA (NCT06995183)
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- E.S.stroes
Left Ventricular Dysfunction, Myocardial Infarction
St. Vincent's Screening To Prevent Heart Failure Study
The STOP-HF study is a prospective, randomized, controlled trial recruiting asymptomatic individuals with risk factors for left ventricular dysfunction from 50 primary care clinics in Dublin and south east Ireland.
- Conditions
- Left Ventricular Dysfunction, Myocardial Infarction, Hypertension, Diabetes
- Trial name
- STOP-HF (NCT00921960)
- Testing
- Intervention Care
- Where
- Ireland
- Volunteers
- 1,378 people
- Sponsor
- St Vincent's University Hospital, Ireland
Heart Health Screening and Prevention
Beauty from Within Community Screening Project
Cardiovascular disease (CVD) is the leading cause of death world-wide in women. Despite current medical advances, heart disease is rising in relatively young women.
- Trial name
- BFW (NCT02588690)
- Testing
- Fingerstick cholesterol test, Atherosclerosis Cardiovascular Disease Risk assessment, Blood pressure measurement
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Atrial Fibrillation
Atrial Fibrillation Screening and Education Study
The purpose of this study is to evaluate the outcomes of a community placed atrial fibrillation (AF) screening and education program
- Trial name
- NCT03440762
- Testing
- AF awareness education
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Mayo Clinic
Cardiovascular Diseases, Cardiovascular Risk Factor
Using Big Data to Conduct Innovative Cardiovascular Clinical Trials
Traditional randomized clinical trials (RCTs) have provided extremely valuable information on medical therapies and procedures that have changed the way heart diseases are treated.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Dyslipidemias
- Trial name
- NCT04067297
- Testing
- Lipid management toolbox
- Where
- Canada
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical Evaluative Sciences
Atrial Fibrillation, Atrial Flutter
DeteCtiON and Stroke PreventIon by MoDEl ScRreenING for Atrial Fibrillation
Atrial fibrillation (AF) is the most common clinical arrhythmia and the prevalence increases with age. AF increases the risk of ischaemic stroke fivefold and accounts for almost one-third of all strokes.
- Trial name
- CONSIDERING-AF (NCT05838781)
- Testing
- Risk prediction model, 14-days continuous ECG monitoring
- Where
- 2 sites in Sweden
- Volunteers
- 2,112 people
- Sponsor
- Bristol-Myers Squibb
Atrial Fibrillation (Prevention of Stroke), Stroke
Digital Screening for Atrial Fibrillation to Prevent Stroke
The Austrian Digital Heart Study is a population-based, siteless, randomized, controlled digital trial testing whether a smartphone-based atrial fibrillation screening and management pathway reduces stroke hospitalizations…
- Trial name
- ADHP (NCT07684053)
- Testing
- Smartphone-based digital atrial fibrillation screening and management pathway
- Where
- Austria
- Volunteers
- 100,060 people
- Sponsor
- Medical University Innsbruck
Atrial Fibrillation (Prevention of Stroke), Arrythmia, Cardiac
Pharmacy-based Opportunistic Atrial Fibrillation Screening Integrated With Emergency Services (NUMAPLUS-FA)
This study evaluates the feasibility and fidelity of an opportunistic atrial fibrillation (AF) screening programme conducted in 38 community pharmacies in Seville (Spain), using the Kardias® 6-lead portable ECG device…
- Conditions
- Atrial Fibrillation (Prevention of Stroke), Arrythmia, Cardiac, Mass Screening, Pharmacies
- Trial name
- Numaplus_FA (NCT07598903)
- Testing
- Integrated pharmacy-based AF screening circuit
- Where
- Spain
- Volunteers
- 380 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Atrial Fibrillation, Stroke
Systematic NT-proBNP and ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm, Sweden - STROKESTOP II
STROKESTOP II will study if the biomarker NT-proBNP together with single-lead ECG can be used as a primary population screening tool for silent atrial fibrillation, and builds on previous results from the STROKESTOP study.
- Trial name
- STROKESTOP II (NCT02743416)
- Testing
- ECG screening (Zenicor-ECG) for atrial fibrillation
- Where
- Sweden
- Volunteers
- 6,868 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Statin, Cardiovascular Risk Factors
Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor…
- Conditions
- Statin, Cardiovascular Risk Factors, Primary Prevention, Adherence, Medication
- Trial name
- RESPECT2 (NCT05725096)
- Testing
- Coronary Computed Tomography Angiography, Traditional cardiovascular risk stratification
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Zhang longjiang,MD
Heavy Smokers, Lung Cancer Screening
Akershus Cardiac Examination (ACE) 5 Study
Individuals with extensive smoking history have 2- to 3-fold increased risk of dying prematurely compared to age- and gender-matched peers.
- Conditions
- Heavy Smokers, Lung Cancer Screening, Cardiovascular Risk Profile, Cardiovascular Disease Prevention
- Trial name
- ACE5 (NCT07301489)
- Testing
- Lung Cancer Screening Plus Program, Standard of Care
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Cardiovascular Disease
The Miami Heart Study at Baptist Health South Florida
The Miami Heart Study at Baptist Health will be an observational, longitudinal and prospective cohort study in a target population of 4000 healthy subjects (40-65 years old) consisting of members from the Greater Miami Area…
- Trial name
- MiHEART (NCT02508454)
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Baptist Health South Florida