Clinical trials: Heart Infarction
Monomorphic Ventricular Tachycardia, Myocardial Infarction
Using Ripple Mapping to Guide Substrate Ablation of Scar Related Ventricular Tachycardia.
The heart beat is controlled by electrical signals. Following a heart attack, part of the heart muscle dies and is later replaced by scar tissue.
- Conditions
- Monomorphic Ventricular Tachycardia, Myocardial Infarction, Dilated Cardiomyopathy
- Trial name
- Ripple-VT (NCT02216760)
- Testing
- Ripple Mapping guided VT ablation, Conventional VT ablation
- Where
- United Kingdom
- Sponsor
- Imperial College London
Acute Heart Failure, Decompensated Heart Failure
Characterisation of phenotYpes in aCute Heart faiLure patiEnts
An observational cohort study to evaluate the benefit of functional parameters, radiomics and blood biomarkers to predict the outcome of patients with acute heart failure.
- Conditions
- Acute Heart Failure, Decompensated Heart Failure, Cardiogenic Shock
- Trial name
- CYCLE (NCT07508891)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Coronary Artery Disease, Myocardial Infarction
Reduction in Infarct Size by Remote Per-postconditioning in Patients With ST-elevation Myocardial Infarction
Trial objective: To test the hypothesis that remote per-postconditioning in connection with primary PCI will reduce myocardial infarct size patients with STEMI.
- Trial name
- RECOND (NCT02021760)
- Testing
- Primary Percutaneous Coronary Intervention
- Where
- 3 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- John Pernow
Ethics, Cardiac Rehabilitation
The Role of 4 Different Consent Approaches on a Pilot Study to Increase Cardiac Rehabilitation Attendance
Cardiac Rehabilitation is a lifestyle and exercise program for patients with heart disease. Cardiac Rehabilitation is strongly recommended in guidelines, but only 30% of eligible patients attend.
- Conditions
- Ethics, Cardiac Rehabilitation, Coronary Heart Disease (CHD), Heart Failure
- Trial name
- MOST-CR (NCT07123480)
- Testing
- Usual Care Group, More Support and Tools
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Baystate Medical Center
Acute Myocardial Infarction
Impact of Guidelines on Cardiovascular and Economic Outcomes With Focus on Lipid Lowering Drugs
Methods: All patients <75 years registered in the Swedish Secondary Prevention after Heart Intensive care Admission registry (SEPHIA), will be followed-up within one year post-myocardia infarction (MI).
- Trial name
- GuLLD (NCT02929550)
- Testing
- Well-controlled
- Volunteers
- 5,304 people
- Sponsor
- Karolinska Institutet
Myocardial Infarction, Acute, Multi-Vessel Coronary Artery Stenosis
Timing of FFR-guided PCI for Non-IRA in STEMI and MVD (OPTION-STEMI)
Patients with STEMI (ST-segment elevation myocardial infarction) with multivessel disease which have PCI (percutaneous coronary intervention)-suitable non-IRA (infarct related artery) will be randomized to immediate complete…
- Trial name
- NCT04626882
- Testing
- Staged in-hospital or Immediate complete revascularization
- Where
- 14 sites in South Korea
- Volunteers
- 994 people
- Sponsor
- Chonnam National University Hospital
Cardiovascular Diseases, Heart Diseases
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events
To explore the role of insulin growth factor in cardiovascular disease in older men and women.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00086424
- Volunteers
- 5,888 people
- Sponsor
- Albert Einstein College of Medicine
Coronary Artery Disease, Ischemic Heart Disease
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
- Trial name
- ECLIPSE (NCT03108456)
- Testing
- Orbital Atherectomy, Balloon
- Where
- 104 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Abbott Medical Devices
Acute Coronary Syndrome
An Intervention to Reduce Prehospital Delay to Treatment in Acute Coronary Syndrome
This study was conducted to test whether a focused education and counseling intervention delivered by a nurse will decrease time of delay in seeking treatment for the signs and symptoms of acute coronary syndrome (i.e., heart…
- Trial name
- PROMOTION (NCT00734760)
- Testing
- education
- Volunteers
- 3,522 people
- Sponsor
- University of California, San Francisco
Stroke, Cardiovascular
Brain and Behavior Correlates of Arm Rehabilitation
This project is designed to use three-dimensional movement analysis and magnetic resonance (fMRI) neuroimaging techniques to examine the brain activity and motor behavior changes associated with constraint-induced (CI) therapy…
- Trial name
- BCAR (NCT04989920)
- Testing
- Experimental group: CIMT group (Constraint-Induced Movement Therapy)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Southern California
STEMI - ST Elevation Myocardial Infarction
Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCI
The RIGHT study is a large randomized study dedicated to post-PPCI anticoagulation in STEMI patients. The investigators propose to evaluate the clinical efficacy and safety of anticoagulation prolonged for at least 48 hours after…
- Trial name
- RIGHT (NCT03664180)
- Testing
- Bivalirudin, Enoxaparin, Unfractionated heparin
- Where
- China
- Volunteers
- 2,989 people
- Sponsor
- Beijing Anzhen Hospital
Acute Myocardial Infarction, Acute Coronary Syndrome
Effectiveness of Advanced Practice Nurse-Led Telehealth on Readmissions
Aim. To develop and examine the effectiveness of an APN-led telehealth rehabilitative programme as a transitional nursing therapeutic on readmission rates and health related outcomes amongst patients with Acute Myocardial…
- Trial name
- ALTRA (NCT02483494)
- Testing
- APN-led Telemedicine
- Where
- Singapore
- Volunteers
- 300 people
- Sponsor
- National University Heart Centre, Singapore
Cardiac Event, Emotions
Emotion Regulation Intervention to Sustain Physical Activity in Rural-dwelling Women and Men After Myocardial Infarction
The purpose of this study is to evaluate early preliminary efficacy of the eMotion intervention in US adults who have experienced a first cardiac event and participating in phase II cardiac rehabilitation.
- Trial name
- eMotion (NCT04441086)
- Testing
- eMotion, Healthy Living Active Control
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Hemorrhage, Cerebrovascular Accident
Antiplatelet Therapy Continuation in Spine Surgery - Its Effect on Postoperative Morbidity and Mortality
The objective of this study is to evaluate the safety of antiplatelet (APA)therapy continuation in patients undergoing lumbar spine surgery (laminectomy, discectomy and foraminotomy), and to gather evidence-based data regarding…
- Conditions
- Hemorrhage, Cerebrovascular Accident, Myocardial Infarction, Pulmonary Embolism
- Trial name
- NCT01006083
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cardiometabolic Syndrome, Hiv
The Role of Ectopic Fat and Heart Attack Risk in HIV
This study is designed to investigate differences between people living with HIV (PLWHIV) and general populations on how the body utilises and stores energy.
- Trial name
- BHIVA (NCT06784154)
- Testing
- Non-interventional
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Acute Myocardial Infarction
The Prognosis of Acute Myocardial Infarction
This study aims to establish a registry and surveillance system for acute myocardial infarction (AMI) patients in Xinjiang, focusing on collecting comprehensive information including basic patient demographics, patient…
- Trial name
- AMI-COPS (NCT02737956)
- Where
- China
- Volunteers
- 7,350 people
- Sponsor
- Xinjiang Medical University
Mobile Health, Acute Myocardial Infarction
M-Health Care for Patients After AMI on Disease Perception, Self-Efficacy, Anxiety and Cardio-Respiratory Fitness
The aim of this study is to explore the overall effectiveness of interventions using mobile health care to improve disease perception, self-efficacy, anxiety, cardio-pulmonary fitness for patients with acute myocardial infarction.
- Conditions
- Mobile Health, Acute Myocardial Infarction, Undefined, Self-efficacy
- Trial name
- NCT04438356
- Testing
- M-Health
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- National Defense Medical Center, Taiwan
Anterior STEMI
The RECOVERY Study: Using Supersaturated Oxygen Therapy To Treat Small Vessel Blockages After a Heart Attack
The study tests whether adding supersaturated oxygen (SSO₂) therapy to standard stent treatment can improve heart recovery after a major heart attack (anterior STEMI).
- Trial name
- NCT07000266
- Testing
- Percutaneous Coronary Intervention (PCI), Diagnostic Imaging, Device Treatment
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacio Privada Mon Clinic Barcelona
Acute Myocardial Infarction (AMI)
TMS for Sympathetic Hyperactivity and Inflammation in Acute Myocardial Infarction
The goal of this clinical trial is to learn whether repetitive transcranial magnetic stimulation (rTMS) can improve sympathetic hyperactivity and inflammatory responses in patients with acute myocardial infarction (AMI), as well…
- Trial name
- NCT07842770
- Testing
- 1-Hz repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Hospital
ST Elevation Myocardial Infarction
The Efficacy and Safety of Low-Level Tragus Stimulation on Heart Rate Variability, Neutrophil-Lymphocyte Ratio, and Major Adverse Cardiovascular Events in Patients With ST-Segment Elevation Myocardial Infarction (TESLA-STEMI)
The goal of this clinical trial is to learn the effect of low level tragus stimulation (LLTS) on heart rate variability (HRV), neutrophil-lymphocyte ratio, and major adverse cardiovascular events in patient with ST-segment…
- Trial name
- TESLA-STEMI (NCT06537583)
- Testing
- Parasym Neuromodulation Device (Treatment Group)
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Diponegoro
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