Clinical trials: Heart Infarction
Acute Myocardial Infarction
Colchicine in ST-elevation Myocardial Infarction
There is evidence that inflammatory processes may play detrimental role during the acute phase of myocardial infarction The hypothesis of this study is that colchicine, by its anti-inflammatory action, may lead to reduction in…
- Trial name
- NCT01936285
- Testing
- Colchicine 2 mg loading dose; 0.5 mg bid for 5 days
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- G.Gennimatas General Hospital
Myocardial Infarction (MI)
Efficacy of Montelukast on STEMl Patients
Acute myocardial infarction (AMI) is one of the leading causes of patient mortality worldwide. Each year, over 8 million people globally die from AMI, with approximately 30% of these cases being ST-segment elevation myocardial…
- Trial name
- NCT07320625
- Testing
- Montelukast
- Where
- 12 sites in China
- Volunteers
- 512 people
- Sponsor
- Shanghai Zhongshan Hospital
Cardiovascular Diseases, Coronary Disease
Natural History of Coronary Heart Disease
To examine the natural history of mortality due to coronary heart disease in post-myocardial infarction patients from the Beta-Blocker Heart Attack Trial (BHAT) and the Aspirin Myocardial Infarction Study (AMIS).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Myocardial Infarction, Heart Diseases
- Trial name
- NCT00005265
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Right Ventricular Infarction
The Effects of Nitric Oxide for Inhalation in Right Ventricular Infarction Patients
This study is designed to better understand the effects of nitric oxide, a gas for inhalation, on patients with right ventricular infarction.
- Trial name
- NCT00782652
- Testing
- inhaled nitric oxide, nitrogen gas
- Where
- 6 sites in United States, Belgium and 3 more
- Volunteers
- 3 people
- Sponsor
- Mallinckrodt
Cardiovascular Diseases, Heart Diseases
Plaque Inflammation and Dysfunctional HDL in AIM-HIGH
Coronary heart disease (CHD) is a serious health concern that affects millions of people in the United States. It is usually caused by atherosclerosis-a condition that occurs when fatty material and plaque build up on the walls…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Atherosclerosis
- Trial name
- HDL Proteomics (NCT00880178)
- Testing
- Simvastatin and Extended-Release niacin, Simvastatin
- Where
- 29 sites in United States, Canada
- Volunteers
- 324 people
- Sponsor
- University of Washington
Shock, Cardiogenic, Myocardial Infarction
Efficacy Study of LV Assist Device to Treat Patients With Cardiogenic Shock (ISAR-SHOCK)
The purpose of this study is to evaluate the efficacy and safety of a left ventricular assist device in comparison to a standard treatment with an intraaortic balloon pump (IABP) in patients with cardiogenic shock due to left…
- Trial name
- NCT00417378
- Testing
- Left Ventricular Assist Device Impella LP 2.5, Intraaortic Balloon Pump
- Where
- 2 sites in Germany
- Volunteers
- 26 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Acute Myocardial Infarction, Ventricular Aneurysm Following Acute Myocardial Infarction
Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm
The study will use 18F-FAPI PET/CT to study myocardial fibrosis in patients diagnosed with myocardial infarction-associated ventricular aneurysm (MI-VA).
- Conditions
- Acute Myocardial Infarction, Ventricular Aneurysm Following Acute Myocardial Infarction, Myocardial Fibrosis
- Trial name
- NCT06994221
- Testing
- 18F FAPI-42 PET/CT scan
- Where
- China
- Volunteers
- 20 people
- Sponsor
- RenJi Hospital
Myocardial Infarction
Effect of Beta-blocker on Cardioprotective Effect of Remote Ischemic Conditioning
Remote ischemic conditioning has been shown to protect myocardium from ischemia-reperfusion injury during cardiac intervention or cardiac surgery.
- Trial name
- NCT03169426
- Testing
- Beta Blockers Carvedilol Phosphate
- Where
- South Korea
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Myocardial Infarction (MI)
Dual Antiplatelet Therapy Strategies After Acute Myocardial Infarction Undergoing PCI: Prasugrel vs Ticagrelor & 12 Months vs 1-3 Months
This study is testing different blood-thinning treatment strategies for people who have had a heart attack and were successfully treated with a coronary stent procedure (PCI).
- Trial name
- STREAMLINE (NCT07507500)
- Testing
- Prasugrel, Ticagrelor
- Where
- 5 sites in Ireland, Latvia and 3 more
- Volunteers
- 8,100 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
ST Elevation Myocardial Infarction (STEMI), Coronary Artery Disease
Metformin to Reduce Heart Failure After Myocardial Infarction
The investigators will evaluate the effect of metformin therapy during 4 months in non-diabetic patients following ST-elevation myocardial infarction on left ventricular ejection fraction as measured with cardiac magnetic…
- Conditions
- ST Elevation Myocardial Infarction (STEMI), Coronary Artery Disease, Heart Failure, Diabetes
- Trial name
- GIPS-III (NCT01217307)
- Testing
- Metformin
- Where
- Netherlands
- Volunteers
- 380 people
- Sponsor
- University Medical Center Groningen
Myocardial Infarction, Myocardial Infarction, Acute
BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Myocardial Infarction
The BIO|GUARD-MI study investigates whether continuous arrhythmia monitoring and the consequent treatment after detected arrhythmias in patients after myocardial infarction with preserved cardiac function, but other risk factors…
- Conditions
- Myocardial Infarction, Myocardial Infarction, Acute, Myocardial Infarction Old
- Trial name
- BIO-GUARD-MI (NCT02341534)
- Testing
- BioMonitor
- Where
- 59 sites in United States, Australia and 12 more
- Volunteers
- 802 people
- Sponsor
- Biotronik SE & Co. KG
Coronary Artery Disease, Myocardial Infarction
Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia
This study is being done to observe the effects of treatment from a device called the Bioboosti which utilizes pulsed electromagnetic waves on its ability to improve blood flow to the heart tissue in individuals with coronary…
- Trial name
- NCT05111288
- Testing
- Pulsed electromagnetic field therapy (PEMF), Inactive Pulsed electromagnetic field therapy (PEMF)
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Mayo Clinic
Myocardial Infarction, Coronary Disease
The MI-HEART Project
The purpose of the study is to examine ways in which a clinical information system can help patients better recognize the signs and symptoms of an acute myocardial infarction (heart attack) and to take actions to decrease…
- Trial name
- NCT00013741
- Testing
- Tailored Education Messages
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Library of Medicine (NLM)
Coronary Heart Disease, Stroke
Surgical Manipulation of the Aorta and Cerebral Infarction
The purpose of the study is to compare two surgical strategies for coronary artery bypass grafting with respect to the occurrence of cerebral infarctions made visible by magnetic resonance imaging
- Conditions
- Coronary Heart Disease, Stroke, Cerebral Infarction
- Trial name
- NCT00558779
- Testing
- OBCAB (Off Pump Coronary Artery Bypass Grafting), CABG (coronary artery bypass grafting)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Wuerzburg
STEMI - ST Elevation Myocardial Infarction
ST-segment Elevation Not Associated With Acute Cardiac Necrosis (LESTONNAC)
Patients with chest pain and persistent ST segment elevation (STE) may not have acute coronary occlusions or serum troponin curves suggestive of acute necrosis.
- Trial name
- LESTONNAC (NCT05689970)
- Testing
- AI platform to detect ST elevation in ECG
- Where
- 7 sites in Spain
- Volunteers
- 420 people
- Sponsor
- Idoven 1903 S.L.
Acute Myocardial Infarction
Japan-Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by ANP
To evaluate whether ANP as an adjunctive therapy for AMI reduces myocardial infarct size and improves regional wall motion.
- Trial name
- NCT00212056
- Testing
- ANP(hANP), Control
- Where
- Japan
- Volunteers
- 600 people
- Sponsor
- National Cerebral and Cardiovascular Center, Japan
Stroke, Ischemic, Stroke, Acute
Ischemic Strokes While on NOAC - How Compliance Matters
This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage.
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke Syndrome, Stroke, Cardiovascular
- Trial name
- NCT04607070
- Where
- Hong Kong
- Volunteers
- 91 people
- Sponsor
- Chinese University of Hong Kong
Coronary Artery Disease, Congestive Heart Failure
Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
The purpose of this study is to investigate the safety of intracoronary cardiac stem cells (CSCs) therapy in humans. Currently, there is no effective intervention to regenerate (regrow) dead heart muscle after a heart attack.
- Trial name
- SCIPIO (NCT00474461)
- Testing
- Treatment group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Louisville
Acute Myocardial Infarction
the Association of Intestinal Microbial Metabolites and Cardiac Function in Acute Myocardial Infarction
Recently, more and more studies have confirmed that intestinal flora is closely related to the occurrence and development of cardiovascular diseases.Bile acids (BAS), short chain fatty acids (SCFA) and trimethylamine oxide…
- Trial name
- NCT04955054
- Testing
- diagnose
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Acute Myocardial Infarction
French Cohort of Myocardial Infarction Evaluation
Over the last two decades, considerable progress has been made in the management of Acute Myocardial Infarction (AMI), both in the acute phase and in monitoring beyond the hospital phase.
- Trial name
- FRENCHIE (NCT04050956)
- Where
- France
- Volunteers
- 30,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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