Clinical trials: Heart Ventricles
Tachycardia, Ventricular
Cardiac RADIoablation Versus Repeat Catheter Ablation: a Pivotal Randomized Clinical Trial Evaluating Safety and Efficacy for Patients With High-risk Refractory Ventricular Tachycardia (RADIATE-VT)
RADIATE-VT is a pivotal, multicenter, randomized trial comparing safety and efficacy between cardiac radioablation (CRA) using the Varian CRA System and repeat catheter ablation (CA), for patients with high-risk refractory…
- Trial name
- RADIATE-VT (NCT05765175)
- Testing
- Varian Cardiac Radioablation (CRA), Catheter Ablation (CA)
- Where
- 11 sites in United States
- Volunteers
- 380 people
- Sponsor
- Varian, a Siemens Healthineers Company
Ventricular Arrythmia
Safety and Efficacy of Catheter Ablation of Idiopathic Ventricular Arrhythmias Arising From Cardiac Outflow Tracts
Ventricular arrhythmias arising from cardiac outflow tract affect quality of life and can cause decrease in left ventricular ejection fraction. Drugs used for treating those arrhytmias may be ineffective or may have side effects.
- Trial name
- NCT03258112
- Testing
- Radiofrequency cardiac catheter ablation
- Sponsor
- Assiut University
Heart Valve Diseases, Aortic Valve Stenosis
BIOVALVE - I / II Clincial Investigation
First-in-Human clinical investigation to evaluate the safety and clinical performance of the BIOVALVE prosthesis in subjects presenting with severe symptomatic aortic valve stenosis, which are as judged by the heart team…
- Trial name
- BIOVALVE (NCT02249000)
- Testing
- BIOVALVE prosthesis
- Where
- 13 sites in Belgium, Germany and 2 more
- Volunteers
- 68 people
- Sponsor
- Biotronik AG
Congenital Heart Disease
Study to Assess Safety of the Pulmonary Valved Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract Reconstruction
The study is a prospective, non-randomised, open label clinical study to assess the safety of the Bioabsorbable Pulmonary Valved (PV) conduit (PV-001) in subjects > 2 years and < 22 years of age, undergoing Right Ventricular…
- Trial name
- NCT02700100
- Testing
- Bioabsorbable Pulmonary Valved Conduit (PV-001)
- Where
- 3 sites in Hungary, Malaysia and 1 more
- Volunteers
- 12 people
- Sponsor
- Xeltis
Heart Failure, Congenital Heart Disease
Ventricular and Pulmonary Vascular Reserve After the Fontan Operation
Aim #1: Define and determine the prevalence of pulmonary vascular disease and diastolic dysfunction as assessed by the gold standard of invasive hemodynamic cardiopulmonary exercise testing.
- Trial name
- NCT03853837
- Testing
- rest-exercise echocardiography
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mayo Clinic
Mitral Regurgitation, Mitral Valve Prolapse
Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery
Study objectives: To assess the impact of mitral valve surgery for mitral regurgitation on ventricular arrhythmic burden and surrogate markers of fibrosis in patients with arrhytmogenic mitral valve prolapse (MVP) from baseline…
- Conditions
- Mitral Regurgitation, Mitral Valve Prolapse, Ventricular Tachycardia
- Trial name
- Mitra-VT (NCT06255457)
- Testing
- Mitral valve surgery
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Tachycardia, Supraventricular, Tachycardia, Ventricular
Accuracy and Safety Study of the Magnetecs CGCI System for Intracardiac Mapping
The Magnetecs Catheter Guidance Control and Imaging (CGCI) system is a magnetic remote navigation system which is comprised of a magnetic chamber of eight electromagnets around the patient torso.
- Trial name
- RICTAM (NCT01222156)
- Testing
- Remote magnetic navigation, Magnetecs Catheter Guidance Control and Imaging system
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Magnetecs Corporation
Premature Ventricular Complex, Electrophysiology
Late Effect of Ablation on Premature Ventricular Complex Ablation
Premature Ventricular Complex (PVC) ablation is performed in certain indications. Generally acutely abolition of PVC at the time of ablation accepted as successful ablation. However in some patients this effect occurs lately.
- Conditions
- Premature Ventricular Complex, Electrophysiology, Ablation
- Trial name
- NCT03249545
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yuksek Ihtisas Hospital
Aortic Stenosis
ACURATE TA™ Valve Implantation Registry: SAVI 2
Post-market registry on ACURATE TA™ Transapical Aortic Bioprosthesis and ACURATE TA™ Delivery System implantation in patients presenting severe symptomatic aortic stenosis to collect continued surveillance data pertaining to…
- Trial name
- TA-SAVI2 (NCT02663375)
- Testing
- ACURATE TA™ Transapical Aortic Bioprosthesis
- Where
- 27 sites in Austria, Germany and 2 more
- Volunteers
- 250 people
- Sponsor
- Symetis SA
Hypotension, Heart Failure
Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy
The DAPA-HF trial demonstrated that dapagliflozin was able to reduce the risk of worsening heart failure events and cardiovascular death comparing to placebo in patients with reduced ejection fraction further to standard of care.
- Trial name
- NCT04575675
- Testing
- Dapagliflozin, Sacubitril-Valsartan, Beta blocker
- Where
- Taiwan
- Volunteers
- 78 people
- Sponsor
- Cheng-Hsin General Hospital
Critical Illness, Elevated Left Atrial Pressure
The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial
This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure…
- Conditions
- Critical Illness, Elevated Left Atrial Pressure, Left Ventricular Diastolic Dysfunction, Echocardiography
- Trial name
- TELAP-ICU (NCT07820319)
- Testing
- Echocardiography
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Aortic Stenosis, Amyloid
Atrial Amyloid May Influence Outcomes in Patients Undergoing Surgical Aortic Valve Replacement
Background (Context): Some older adults who undergo surgery to replace a narrowed heart valve (called aortic stenosis) may also have small protein deposits in their heart.
- Trial name
- AORTICMARKER (NCT07105501)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Germans Trias i Pujol Hospital
Ventricular Tachycardia, Arrythmia
Rook Epicardial Access Device Study
The purpose of this study is to confirm the efficacy and safety of the Talon Surgical Rook® Epicardial Access Kit as a pericardial access device.
- Trial name
- NCT03427333
- Testing
- The Rook® Epicardial Access Kit
- Where
- Czechia
- Volunteers
- 13 people
- Sponsor
- Talon Surgical
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Tachyarrhythmia, Atrial Flutter
MCG for Localization of Tachyarrhythmia's Origin
This is an exploratory research aiming to accurately identify the site of origin of tachyarrhythmia using Magnetocardiography (MCG), which will have guiding significance for early diagnosis, the formulation of treatment plans and…
- Conditions
- Tachyarrhythmia, Atrial Flutter, Paroxysmal Supraventricular Tachycardia, Atrial Tachycardia
- Trial name
- NCT06327425
- Testing
- Magnetocardiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Qilu Hospital of Shandong University
Heart Disease, Congenital, Single Ventricle
Single Ventricle Outcome
The objective of this research proposal is to perform an ongoing single institution prospective clinical trial examining the overall clinical outcome of children with single ventricle physiology.
- Conditions
- Heart Disease, Congenital, Single Ventricle, Hypoplastic Left Heart Syndrome
- Trial name
- NCT00308217
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Single-ventricle
Impact of Early Fortini Initiation on Growth and Interstage Outcomes in Infants With Single Ventricle Physiology
This study is testing whether a special formula called Fortini, which is a high-calorie, low osmolality formula can help high-risk babies with single ventricle physiology grow better after their initial Stage 1 surgical…
- Trial name
- NCT07087782
- Testing
- Fortini formula, Standard Nutritional Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Driscoll Children's Hospital
Arrhythmia, Heart Diseases
Antiarrhythmic Effects of N-3 Fatty Acids
To determine the antiarrhythmic effects of dietary N-3 fatty acids in patients with implanted defibrillators.
- Conditions
- Arrhythmia, Heart Diseases, Tachycardia, Ventricular, Ventricular Fibrillation
- Trial name
- NCT00004558
- Testing
- dietary n-3 polyunsaturated fatty acids
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ventricular Arrythmia
China Inherited Ventricular Arrhythmias Registry
This is an observational, prospective, multi-center registry, aiming at building a risk stratification for malignant inherited ventricular arrhythmias, including Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT…
- Trial name
- NCT03880708
- Where
- China
- Volunteers
- 500 people
- Sponsor
- China National Center for Cardiovascular Diseases
Aortic Stenosis, Severe
The CardioFit Trial: Exercise Training Before Aortic Valve Surgery
The CardioFit Trial: The feasibility, safety and tolerability of an exercise training programme in patients with severe aortic stenosis prior to aortic valve replacement surgery: A feasibility trial To investigate if a Structured…
- Trial name
- CardioFit (NCT06818110)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust