Clinical trials: Heartburn
Reflux Oesophagitis
Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers
The objectives of this study were: To compare repeated doses of YF476 at 2 dose levels, placebo and omeprazole with respect to their effect on basal- and food- stimulated gastric pH in healthy volunteers.
- Trial name
- NCT01599858
- Testing
- YF476, Omeprazole
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.
Healthy
The Effect of Cinacalcet on Gastric Acid Output in Healthy Subjects
The purpose of this study is to determine whether cinacalcet will increase gastric acid secretion in healthy volunteers.
- Trial name
- NCT00336739
- Testing
- cinacalcet
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Tufts University
Gastroesophageal Reflux Disease
The Effect of High PCO2 Solution on Esophageal Acid Sensation
To determine the effect of intraesophageal high PCO2 solution as compared to acidic and saline solutions on subjects' heartburn sensation using stiumlus-response functions.
- Trial name
- PC02 (NCT01128608)
- Testing
- 24-Hr Esohpageal pH Monitoring, PCO2 Acid Perfusion and 0.1N HCI Perfusion
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Premature Birth of Newborn
Skin Maturation in Premature Infants
The skin barrier lipids will be lower in premature infants than in full term infants and will become normal over 3-4 months after birth.
- Trial name
- NCT01619228
- Where
- 2 sites in United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy
Acidity Level of Blood From Primary Molar's Pulp While Undergoing Pulpotomy or Pulpectomy Procedure
The aim of this study is to evaluate the level of acidity of blood samples that are been taken from pulp chambers of primary molars undergoing pulpotomy or pulpectomy procedures.
- Trial name
- NCT01486537
- Where
- Israel
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Erosive Reflux Disease
Study to Evaluate the Efficacy and Safety of Tegoprazan in ERD Patients With Nighttime Heartburn and Sleep Disturbance
This study aims to compare the nighttime heartburn and sleep disturbance improvement effect of Tegoprazan 50mg and Eomeprazole 40mg in patients with ERD patients.
- Trial name
- NCT04309916
- Testing
- Tegoprazan, Esomeprazole
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Postprandial Heartburn
Safety and Efficacy of IQP-LH-101 in Postprandial Heartburn
This study is a randomized, placebo-controlled, single-blind, three-way crossover clinical trial to evaluate safety and efficacy of IQP-LH-101 (tablet form and liquid form) in postprandial heartburn.
- Trial name
- NCT01718639
- Testing
- IQP-LH-101 tablet, IQP-LH-101 liquid
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Heartburn
A Study to Assess the Bioequivalence of Famotidine Chewable Tablets and Film-Coated Tablets (0208-144)
This study will determine whether the CT formulation of famotidine taken with and without water is bioequivalent to the FCT formulation.
- Trial name
- NCT00945750
- Testing
- Famotidine FCT, Famotidine CT
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Hypergastrinaemia
Effect of Single Doses of YF476 on Stomach Acidity
The objective of the study was to assess the effect of a range of single oral doses of YF476 on pentagastrin-induced gastric acid output in healthy volunteers
- Trial name
- NCT01601418
- Testing
- YF476
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.