Clinical trials: Heartfailure
Pacemaker, Heartfailure
The Effect of CRT on the Frank Starling Mechanism
The investigators are examining a scientific principle called the Frank Starling Mechanism and how it relates to Cardiac Resynchronisation Therapy (CRT), a form of pacemaker therapy used in the treatment of heart failure.
- Trial name
- CRT (NCT05993585)
- Testing
- Test Of The Frank Starling Mechanism - Adjustment Of Av Delay And Measurement Of Pre-load -Control, Other: Test Of The Frank Starling Mechanism - Adjustment Of Av Delay And Measurement Of Pre-load -CRT
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Heartfailure
Mbarara Acute Heart Failure Registry
This is a prospective cohort to describe clinical characteristics, predictors of poor outcomes both during hospitalization and at home, functional status, and quality of life among patients aged 13 years or more, consecutively…
- Trial name
- MAHFER (NCT02721030)
- Where
- Uganda
- Volunteers
- 217 people
- Sponsor
- Mbarara University of Science and Technology
Heartfailure
Maximizing CRT Delivery by Using MultipolAr Coronary Sinus Lead FamiLy ACUITY® X4 - RALLY X4 Study
The objective of this study is to collect clinical data on safety and performance of ACUITY X4® leads when used in a standard clinical setting.
- Trial name
- RallyX4 (NCT02066467)
- Testing
- Left Ventricular lead implant: ACUITY X4® Lead Family
- Where
- 83 sites in Austria, Belgium and 16 more
- Volunteers
- 863 people
- Sponsor
- Boston Scientific Corporation
Decompensated Heartfailure, Cardio-renal Syndrom
Nasal High Flow at Acute Hart Failure
The pilot study aims to compare the results of using a new respirator (OPTIFLOW TM-High-Flow-Machine) with those from Standard-Oxygen-Therapy during the stabilization of patients who have been hospitalized due to acute heart…
- Trial name
- NCT02058810
- Testing
- Nasal high flow, Conventional nasal oxygen
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- University Hospital Regensburg
Hypervolemic Hyponatremia
International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
To demonstrate that after 12 weeks of open-label lixivaptan treatment, serum sodium is maintained in hyponatremic patients continuing to receive lixivaptan compared to placebo during the 4 week double blind treatment period.
- Trial name
- NCT00876876
- Testing
- Lixivaptan
- Volunteers
- 300 people
- Sponsor
- CardioKine Inc.
Heart Failure, Diastolic, Edema Brain
Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure
The study aims at assessing the usefulness of the Heartfelt1 device in patients suffering from heart failure, who have peripheral oedema. The device is non-contact and does not requires patient compliance to work.
- Conditions
- Heart Failure, Diastolic, Edema Brain, Decompensated Heartfailure
- Trial name
- NCT02993601
- Testing
- Heartfelt-1, Weighing scales, Medical grading of oedema
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Heartfelt Technologies