Clinical trials: Heat
Chronic Stable Angina Pectoris
The Heat Transport Characteristics of the Heart and Lung Meridians: A Study of CSAP Patients and Healthy Adults
Although some important progresses were made in the field of the meridian research, no breakthroughs have been achieved. Besides,there are some problems in meridian researches.
- Trial name
- NCT04264559
- Testing
- Infrared thermal imaging, Moxibustion
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Physiological Strain
The Affect of a Ventilated Helmet on Physiological Load
The use of infantry helmets under heavy heat stress conditions, during physical exertion, may hinder the body's ability to effectively dissipate heat from the head area, thereby damaging the soldier's function.
- Trial name
- NCT01595906
- Testing
- Ventilated Helmet
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Menopause, Aging
Role of Menopause in Thermoregulation
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events.
- Trial name
- NCT06798571
- Testing
- Elagolix Oral Tablet, Estradiol patch
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Penn State University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Back Pain
Heat Wrap Device Safety With Age and Body Fat
This study is designed to compare the safety, as measured by skin findings and adverse events, of two different heat devices in elderly, overweight, and elderly and overweight subjects.
- Trial name
- NCT01355653
- Testing
- thermal therapy, ThermaCare heatwrap
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pfizer
Gastroenteritis Escherichia Coli
Phase I Study of ETEC Vaccine
The purpose of this study is to learn if a new candidate vaccine (dmLT) against ETEC (E. coli infection) is safe. This vaccine will be tested to see what effects it has on the body and the ability of the vaccine to help the body…
- Trial name
- NCT01147445
- Testing
- Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pharmacokinetic
Multi-Centre, Open-Label, Two Segment, Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise
Comparison of the plasma PK after single use of 100 mg ketoprofen from Diractin®. 50 mg applied on 2 major joints to 400 mg ketoprofen from Diractin® (100 mg applied to 4 joints - overexposure) 100 mg and 400 mg ketoprofen from…
- Trial name
- NCT00745264
- Testing
- Diractin
- Where
- 2 sites in Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IDEA AG
Acute Exercise, Probiotics
Probiotic Supplementation and Exercise Performance in the Heat
Endurance athletes will be invited to participate in the following study. Subjects will visit the laboratory on three occasions, each time following an overnight fast.
- Trial name
- NCT05389033
- Testing
- Probiotic bacteria
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Total Abdominal Hysterectomy
Are Sutures Required in Total Abdominal Hysterectomy? A Randomised Control Trial
The Hypothesis of this study is that performing total abdominal hysterectomy using the newer electrocoagulation forceps, specifically, the gyrus open seal forceps, curved, compared to the traditional clamp \& suture technique…
- Trial name
- NCT00484835
- Testing
- Performing abdominal hysterectomy using gyrus electrocoagulation forceps
- Where
- 3 sites in Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern Health
Anesthesia, Hypothermia
Comparisons of Two Different Type Heater in Different Inhalation Anesthesia in Terms of Prevention of Hypothermia
Unintentional perioperative hypothermia is a common occurrence. One of the recommendations of the guidelines to prevent hypothermia is the use of active warmers.
- Conditions
- Anesthesia, Hypothermia, Heat
- Trial name
- NCT06107647
- Testing
- COVIDIEN WarmTouch
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Muscle Recovery, Muscle Soreness
Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy
To determine if modalities designed to improve blood flow combined with post-exercise nutrient intake will improve replenishment of muscle glycogen better than nutrient intake alone.
- Conditions
- Muscle Recovery, Muscle Soreness, Glycogen Depletion
- Trial name
- NCT04371237
- Testing
- Compression sleeve, Heat therapy, Glycogen-depleting exercise session
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Physical Activity, Health Behavior
Comparing Two Different Methods to Prescribe Exercise
Practical interventions are needed to increase physical activity (PA) levels in insufficiently active individuals. HEAT is a randomized controlled trial comparing two different exercise prescription (ExRx) methods to increase PA…
- Trial name
- HEAT (NCT04286919)
- Testing
- A Randomized Controlled Trial Comparing the Physical Activity Guidelines for Americans to a New Method of Exercise Prescription Among College Students
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Heat Stroke, Heat Exhaustion
Chemical Ice Packs for Cooling Hyperthermic Patients
A common tool to cool people in the pre-hospital setting is the chemical ice pack. These are used by athletic trainers, EMS personnel, ER staff, and people in the prehosoital setting.
- Trial name
- NCT01694290
- Testing
- Chemical Cold Pack
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sexual Dysfunction, Physiological
Effect Of Menstrual Cycle On Vaginal Blood Flow In Pre-Menopausal Healthy Women.
The Pfizer developed Heat Wash-Out (HWO) system is a software controlled electromechanical system designed to measure vaginal wall blood flow. A small vaginal probe is attached to a control unit. Output data is collected on a PC.
- Trial name
- HWO VBF (NCT00443027)
- Testing
- Vaginal Heat Wash-Out Device
- Where
- 2 sites in Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Body Temperature Changes, Heat Stress
Ambient Temperature and Thermoregulation During Exercise in Children and Youth
Little is known about how children and youth regulate body temperature during exercise across different environmental temperatures compared with young adults, including whether differences in whole-body heat exchange contribute…
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781605
- Testing
- Exercise at 22°C, Exercise at 26°C, Exercise at 31°C
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Obesity, Lung Functions
The Effect of CLA on Obesity, Lung Functions, Lipid Profile and Inflammation in Women With BMI≥25
Conjugated linoleic acid or CLA, is one of the food supplements that could be found in meat, fats, and dairy products of ruminants which has been fed grass not on grains.
- Conditions
- Obesity, Lung Functions, Inflammation, Lipid Disorder
- Trial name
- NCT04641494
- Testing
- Conjugated linoleic acid, High oleic acid safflower oil capsules
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Chester
Cigarette Smoking
The Effect of Smoking on Thermoregulation
To the best of our knowledge, a possible relation between smoking and heat injuries or heat intolerance was never scientifically examined, although such a relation is logical according to the observations that smoking has a…
- Trial name
- NCT01596556
- Testing
- Nicotine, cigarette smoking
- Where
- Israel
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Heat Stress, Exertional, Heat Acclimation and Thermotolerance
Acute Exercise With Overdressing
The purpose of this study is to determine if exercise with extra clothing in a gym-like environment can increase body temperatures appropriately to help people adapt to the heat.
- Trial name
- Acute-XO (NCT07080853)
- Testing
- Exercise with Overdressing, Control Exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Human Papilloma Virus
A Cohort Study of Hyperthermia and Imiquimod for the Treatment of Flat Warts
flat warts are a superficial viral skin disease, extremely common in childhood.Treatment of warts is often difficult and involves different destructive procedures.Although several pharmacological and physical topical treatments…
- Trial name
- NCT05146895
- Testing
- Imiquimod treatment, Local Hyperthermia at 44℃
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Heart Failure With Preserved Ejection Fraction, Obesity, Mild
Hospital Register of Decompensated Heart Failure With Preserved Ejection Fraction
Study Aim is creation of the Hospital Register of patients with heart failure with preserved ejection fraction (HFpEF) for a comprehensive assessment of the influence of gender characteristics, clinical and anamnestic factors…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Obesity, Mild, Decompensated Heart Failure
- Trial name
- NCT06114498
- Testing
- Echocardiography, Bioimpedance, Immunoassay
- Where
- 2 sites in Russia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine