Clinical trials: Heat Effect
Eyelid Diseases
Clinical Safety Study on an Eyelid Warming Device to Evaluate the Eyelid and Cornea Temperature in Healthy Volunteers
The eyelid warming device is designed to relieve the symptoms of dysfunction of the glands in the eyelids. Prospective, non comparative, open, monocentre study.
- Trial name
- NCT01086943
- Testing
- LT2420
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Healthy Subjects
Activation of A-delta-fibres and C-fibres in a First Degree Thermal Injury in Volunteers
The aim of this study is to measure reaction times and thermal detection thresholds to CO2 laser stimulation of the skin, before and after a first degree thermal injury, in the primary and secondary hyperalgesia area, in order to…
- Trial name
- BI-Laser (NCT02442726)
- Testing
- CO2-Laser stimulation (Laser Stimulation Device, SIFEC)
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hot Weather; Adverse Effect, Kidney Dysfunction
Renal Considerations in the Heat Stress Recommendations
An epidemic of chronic kidney disease is occurring in laborers who undertake physical work outdoors in hot conditions. The reason for this is unknown, but may be related to kidney dysfunction caused by increases in body…
- Conditions
- Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia
- Trial name
- Aim1 (NCT04767347)
- Testing
- 23.0°C WBGT - Fixed Work Rate, 25.5°C WBGT - Fixed Work Rate, 27.5°C WBGT - Fixed Work Rate
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Indiana University
Postpartum Hemorrhage
Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study
This study seeks to assess whether populations of women in Latin America outside Quito, Ecuador are at increased risk for developing elevated body temperature above 40.0°C following PPH treatment with 800mcg sublingual…
- Trial name
- NCT02163616
- Testing
- Misoprostol
- Where
- 2 sites in Argentina
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Weather Risk Perception
Perceptions of Weather Risks and Climate Beliefs Among the Hong Kong General Public
Background: Local abnormal heat events may be used as proxies for communicating the health impacts of climate change when people physically feel the effects to reduce the psychological distance of climate change and improve…
- Trial name
- NCT04919148
- Testing
- Heat risk and pro-environment behavior message
- Where
- Hong Kong
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
DYSMENORRHEA
Heat Application on Depression, Anxiety, Menstrual Attitude and Dysmenorrhea
AIM: Establishing the effects of heat application on depression, anxiety, menstrual attitude and severity of dysmenorrhea. METHODS: This randomized controlled prospective experimental trial was conducted with 43 students who were…
- Trial name
- NCT04572555
- Testing
- Heat Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Range of Motion, Articular
Different Therapeutical Modalities Associated to Hamstring Flexibility Training
The purpose of this study is to compare the acute effect of the use of different thermal modalities associated to the training of passive flexibility of the hamstring muscles in the amplitude of motion of the knee extension.
- Trial name
- NCT03021850
- Testing
- Flexibility training with or without different thermal modalities
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Pain, Acute
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
The goal of this research study is to find out how well oxytocin works to reduce pain. Oxytocin will be given intravenously (IV) and as a nasal spray.
- Trial name
- NCT07053774
- Testing
- Intravenous oxytocin, Intranasal oxytocin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hyperthermia, Heat; Weather
Protective Cooling Measures to Safeguard Elderly People From Dangerous Summer Heat
With the increasing incidence and severity of extreme heat events accompanying climate change, there is an urgent need for sustainable cooling strategies to protect heat-vulnerable older adults, who are at increased risk of…
- Conditions
- Hyperthermia, Heat; Weather, Aging, Type2 Diabetes
- Trial name
- NCT05274009
- Testing
- No cooling (control), Recommended cooling, Hybrid cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Hyperthermia, Chronic Primary Pain
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the…
- Conditions
- Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease
- Trial name
- HYPPRI-1 (NCT07101978)
- Testing
- serial whole body hyperthermia
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Healthy
The Effect of the Nature And Frequency of a Stimulation on the Amplitude of the Temporal Summation of Pain
Temporal summation is a mechanism that enhances pain perception. It is a natural mechanism present in most individuals. Generally, temporal summation is measured by the application of a moderately painful stimulation for several…
- Trial name
- NCT05006066
- Testing
- Temporal Summation
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Sarcopenia
Passive Heat Treatment and Skeletal Muscle Reconditioning Older Adults
Rationale: Aging is accompanied by impairments in the sensitivity of skeletal muscle tissue to respond to the anabolic properties of protein feeding, which is suggested to result in age-related loss in muscle mass.
- Trial name
- Sauna (NCT05129995)
- Testing
- Passive heat treatment
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Energy Metabolism
Lactate Profile and Fat Oxidation During Exercise
The goal of this clinical trial is to test whether changes in lactate kinetics during exercise (due to glycogen depletion or hyperthermia) alter the pattern of fat oxidation during a maximal incremental cycle ergometer test in…
- Trial name
- LacFat (NCT05703100)
- Testing
- Incremental exercise test, Incremental exercise test under hyperthermia, Incremental exercise test under glycogen depletion
- Where
- Spain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Smoking Behaviors
Heat-not-burn Tobacco Product to Aid in Switching From Combustible to Noncombustible Nicotine (IQOS)
A novel heat-not-burn tobacco product (IQOS) will be provided to smokers, compared against a (cigarette) smoking as usual period in counter-balanced order in a cross-over design.
- Trial name
- IQOS (NCT04861428)
- Testing
- IQOS, Smoking as Usual
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Frailty, Dementia
HEalthy Aging Team Supported Home-care Services (HEAT-YASAM)
Depending on the YASAM project which was established to home-visit evaluate community-dwelling older adults (80 years of age and over), we aimed to determine the prevalence (prevalence) of geriatric syndromes (dependence…
- Conditions
- Frailty, Dementia, Depression, Malnutrition
- Trial name
- HEAT-YASAM (NCT05993572)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital