Clinical trials: Heathy Volunteer
Heathy Volunteer, Parkinsonian Syndromes
Ultralow Dose PET Imaging of 18F-FDOPA
The goal of this clinical trial is to evaluate an investigational ultralow dose PET imaging technique for Parkinsonian syndromes, neuroendocrine tumors, and gliomas detection and monitoring.
- Conditions
- Heathy Volunteer, Parkinsonian Syndromes, Neuroendocrine (NE) Tumors, Gliomas
- Trial name
- NCT07542158
- Testing
- 18F-FDOPA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Akiva Mintz
Bioavailability Heathy Volunteers, Safety
Pharmacokinetics and Safety of a New Micellar Glutathione Formulation
This study seeks to determine the short-term effects of daily oral supplementation with a new micellar Glutathione formulation (LipoMicel) on the oral absorption and safety of glutathione in healthy volunteers.
- Trial name
- NCT06345950
- Testing
- Liposomal Glutathione, Standard Glutathione, New Micellar Glutathione (Lipomicel)
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Factors Group of Nutritional Companies Inc.
COVID-19
A Clinical Trial to Assess the Safety and Immunogenicity of Nanocovax in Heathy Volunteers
The purpose of this study is to assess the safety, tolerability, and immunization of Nanocovax in healthy volunteers.
- Trial name
- NCT04683484
- Testing
- Nanocovax
- Where
- Vietnam
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Nanogen Pharmaceutical Biotechnology Joint Stock Company
Bioavailability Heathy Volunteers, Bioavailability Study
Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state.
Two way, two parallel groups, crossover study to compare the bioavailability of 150 mg and 300 mg trazodone hydrochloride (new polymer) (Angelini Pharma S.p.A.) vs.
- Conditions
- Bioavailability Heathy Volunteers, Bioavailability Study, Bioequivalance
- Trial name
- NCT06773767
- Testing
- 150 mg trazodone hydrochloride, 300 mg trazodone hydrochloride
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Fibromyalgia, Heathy Volunteers
Traduction and Validation of the Central Sentitization Inventory Into French
The study will include a translation of the Central Sensisization Inventory into French and a cultural validation of the French version of the questionnaire (Reliability, discrimination and comparison with other questionnaires).
- Trial name
- NCT02270775
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Bioavailability Heathy Volunteers
Bioavailability and Bioequivalence Study of Extended Release Torsemide and Spironolactone
To study intrasubject variability and steady-state pharmacokinetics of multiple-doses of Extended Release Torsemide and Spironolactone Fixed Dose Combination (FDC) tablets given together in healthy adult subjects.
- Trial name
- NCT07046975
- Testing
- Torsemide and Spironolactone tablet, Torsemide Tablets and Spironolactone Tablets
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Drug-Drug Interaction, Heathy Volunteer
Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity
Primary objective: 1. To assess the potential inhibitory and inducing effect of oral givinostat on the single dose pharmacokinetics (PK) of intravenous or oral midazolam. 2.
- Trial name
- NCT05492318
- Testing
- Givinostat 10 mg/mL, Midazolam 1mg/ml IV, Midazolam 2.5 mg oromucosal solution
- Where
- Portugal
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Italfarmaco
Heathy Volunteer
A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects
This is a four-part study to evaluate the effect of multiple doses of CC-90001 on the PK, safety, and tolerability of single doses of omeprazole, midazolam, warfarin, rosuvastatin, metformin, digoxin, and nintedanib in healthy…
- Trial name
- NCT03363815
- Testing
- CC-90001, Omeprazole, Midazolam
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Celgene
Heathy Volunteers
Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Acebilustat (CTX-4430)
This is a single-centre, open-label, non-randomised, single oral dose study in healthy male subjects. It is planned to enroll and dose 6 subjects.
- Trial name
- NCT03964558
- Testing
- [14C]-acebilustat solution
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Celtaxsys, Inc.
Healthy Subjects
Stools and Life Habits Collection in Heathy Volunteers/Subjects - to Provide Material for in Vitro Model Development
The purpose of this clinical study is to collect well characterized stools from healthy adult subjects, with completed life habits and alimentary questionnaires.
- Trial name
- PEPSIIN (NCT04301973)
- Testing
- Stool collection
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Bioavailability Heathy Volunteers, Bioavailability and AUC
Bioavailability of Phlorotannins and Carotenoids Following the Intake of Crackers Fortified With Seaweed
The study aims to evaluate the bioavailability of phlorotannins and carotenoids from the seaweed Himanthalia elongata in healthy individuals after the consumption of a cracker fortified with this plant species.
- Trial name
- BIO-ALGA (NCT07508735)
- Testing
- Seaweed cracker, Control cracker
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Bioavailability Heathy Volunteers
A Study to Evaluate the Effect of Food or no Food on the Bioavailability of an Extended Release (ER) Torsemide and Spironolactone Fixed Dose Combination (FDC) Tablet in Healthy Adult Subjects
This study will examine comparative bioavailability of single dose of a fixed dose combination (FDC) of extended release Torsemide and Spironolactone given with or without food in healthy adult subjects.
- Trial name
- NCT07043634
- Testing
- FDC (24 mg ER torsemide and 30 mg Spironolactone) without food, FDC (24 mg ER torsemide and 30 mg Spironolactone) with food
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Bioavailability Heathy Volunteers
Study to Investigate if the Uptake of Ticagrelor Into the Body Differs Depending on Method of Administration.
Study to investigate if the uptake of Ticagrelor into the body differs depending on method of administration.
- Trial name
- NCT01887626
- Testing
- Ticagrelor 90 mg whole tablet, Ticagrelor 90 mg tablet crushed, Dispersed ticagrelor 90 mg tablet suspended in water - nasogastric tube
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Tuberculosis
Safety and Challenge Study of BCG TICE(R) Vaccination to Test Tuberculosis Immunity in Heathy Humans
A nonrandomized, open-label trial will be conducted with a total of 64 healthy male and non-pregnant females, ages 18-45 years. Participants in Group A will enroll 32 participants to receive 2x10^6 colony- forming units CFU…
- Trial name
- NCT06845358
- Testing
- BCG TICE strain, Sodium Chloride, 0.9%, Sterile Water for Injection
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Heathy Volunteers, Smokers
Repair, Remodeling and Regeneration of the Bronchial Epithelium of COPD Patients
COPD is characterized by exagerated decline FEV1 related to obstructive non reversible airflow. This could be the consequence of structural changes and inflammatory pattern of the bronchial wall.
- Conditions
- Heathy Volunteers, Smokers, COPD
- Trial name
- RRR (NCT02354677)
- Testing
- In vitro experiments on bronchial epithelial cells
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Heathy Volunteer
Food-effect on PK and PD of Single Oral Dose of HIP1601 in Healthy Male Subjects
Primary objective To evaluate food effect on the pharmacokinetics (PK) of a single oral dose of HIP1601 in healthy subjects under fed or fasting condition.
- Trial name
- NCT03882112
- Testing
- HIP1601 40mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Heathy Volunteers
Bioequivalence Study Comparing Single Dose of Ferrinemia® Injection With a Single Dose of Venofer® Injection in Healthy Male Volunteers
The aim of this pharmacokinetic study is to assess the bioequivalence of the generic Ferrinemia® Iron Sucrose injection solution 20 mg/mL manufactured by Help S.A., Greece (test product), to Venofer® Iron Sucrose injection…
- Trial name
- NCT03093883
- Testing
- Ferrinemia, Venofer
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Azad Pharma AG