Clinical trials: Helicobacter
Helicobacter Infections
Breath Ammonia Method for H. Pylori Detection: Phase II
The objective is to evaluate the utility of a breath ammonia sensing device. In this study we will assess the effect of H. pylori infection on breath ammonia levels by measuring whether there is a change in the pattern or…
- Trial name
- NCT00194688
- Testing
- H. pylori treatment
- Where
- United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Washington
Helicobacter Pylori Infection
A Clinical Trial on the Efficacy of Gastric Probiotics in the Treatment of Helicobacter Pylori Infection
The purpose of this study is to assess the safety and efficacy of Lactobacillus plantarum, Bacillus coagulans and Lactobacillus plantarum + Bacillus coagulans for eradication of Helicobacter Pylori, as well as the efficacy of…
- Trial name
- NCT05483660
- Testing
- Lactobacillus plantarum, Bacillus coagulans, Lactobacillus plantarum + Bacillus coagulans
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
H Pylori Infection, H Pylori Gastritis
Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community- AIM 1
H. pylori is an infection of the stomach that can cause chronic gastritis, gastric cancer and peptic ulcer disease. The goal of this study is to screen people for this infection and offer treatment for those who test positive for…
- Conditions
- H Pylori Infection, H Pylori Gastritis, Gastric Cancer
- Trial name
- NCT07224035
- Testing
- PYTEST® 14C-Urea Breath Test, VOQUEZNA® Triple Pak®
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
Concomitant Infection of Intestinal Parasites and Helicobacter Pylori
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in…
- Trial name
- NCT05360940
- Testing
- H.pylori stool antigen rapid test and stool parasitological examination
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Melatonin Deficiency
Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia
Background: The aim of the study was to assess the role of melatonin in chronic dyspepsia in this group of women, with consideration of Helicobacter infection.
- Trial name
- NCT04352062
- Testing
- Melatonin, Pantoprazole 40mg, Amoxicillin
- Where
- Poland
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
H. Pylori Infection
Efficacy of 10-day and 14-day Sequential Therapy Versus Triple Therapy on the Eradication of Helicobacter Pylori
Background: Helicobacter pylori infection has been shown to be associated with the development of gastric cancer and peptic ulcer diseases. Eradication of H.
- Trial name
- NCT01042184
- Testing
- Sequential therapy for 14 days, Sequential therapy for 10 days, Triple therapy for 14 days
- Where
- Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori Infection
The Safety and Tolerability, Pharmacokinetics of TNP-2092 Capsules in Combination With Rabeprazole Sodium Enteric-coated Tablets
A phase 1, single-center, double-blind, randomized, placebo-controlled clinical trial to evaluate the safety and tolerability, pharmacokinetics, and preliminary efficacy of multiple administrations of TNP-2092 Capsules in…
- Trial name
- NCT06337604
- Testing
- TNP-2092 capsules, Rabeprazole sodium enteric-coated tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TenNor Therapeutics Inc.
Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Changes Associated With H. Pylori and Gastric Carcinogenesis
This is a research study for patients who currently have or previously had an H. pylori infection or who have gastric or esophageal cancer and who plan to undergo an endoscopy as part of their care.
- Trial name
- IIT H pylori (NCT02164409)
- Testing
- Endoscopy tissue collection
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Helicobacter
Efficacy of Probiotics in the Gut Microbiota and H Pylori Density
We aimed to assess the efficacy of Lactobacillus acidophilus and Lactobacillus rhamnosus in the reduction of bacterial load of H.
- Trial name
- NCT02725138
- Testing
- Probiotic
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Statistical Center, NTUHCTC
Gastric, Peptic Ulcer
Ulcer Pomegranate Muffins
Pomegranate (Punica granatum L.) peel powder, known for its potent antioxidant, anti-inflammatory, and antimicrobial properties, has shown promise in the dietary management of gastrointestinal disorders.
- Trial name
- NCT07123259
- Testing
- WHOLE WHEAT MUFFIN, 1.5g enriched pomegranate muffins, 3g enriched pomegranate muffins
- Where
- Pakistan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Helicobacter Pylori Infection Helicobacter Pylori Eradication Patient Education
Comparing the Efficacy of WeChat-based Patient Education and Conventional Patient Education in the Management of Helicobacter Pylori Eradication
we conducted a retrospective study to compare the efficacy of WeChat-based patient education and conventional patient education in the management of Helicobacter pylori eradication.
- Trial name
- NCT05186662
- Testing
- patient education
- Where
- China
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- Shandong University
Functional Dyspepsia, Gastritis
The Prevalence and the Pathophysiological Role of Non-Helicobacter Pylori Helicobacter Spp. in Well-defined Gastric Diseases and (Pre-) Malignancies
The goal of this clinical trial is to discover the prevalence of NHPH bacteria (Non-Helicobacter pylori Helicobacter species) in patients with one of the following conditions: 1.
- Conditions
- Functional Dyspepsia, Gastritis, Gastritis Chronic, Gastric Cancer (GC)
- Trial name
- HELIS (NCT07770126)
- Where
- 3 sites in Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Helicobacter Pylori Infection
White Light Endoscopy and Magnifying Endoscopy in Assessing the Status of Hp Infection
By comparing the characteristics of Helicobacter pylori (Hp) infection under magnifying endoscopy and white light endoscopy, and making judgments of Hp infection status, the advantages and disadvantages of the two endoscopic…
- Trial name
- NCT06397066
- Testing
- White light endoscopy group, Magnifying endoscopy group
- Where
- China
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Jilin University
Helicobacter Infections, Stomach Neoplasms
Helicobacter Pylori Eradication to Prevent Gastric Cancer
Gastric cancer is the fourth most common type of cancer and the second leading cause of cancer-related death in the world. In China, more than 390,000 new patients are diagnosed with gastric cancer and more than 300,000 patients…
- Trial name
- NCT01133951
- Testing
- OAC triple therapy
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Jie-Jun Wang
Helicobacter Pylori, Safety
PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study
This is a multi-center, non-randomized, open label study. Subjects will be enrolled on a walk-in basis. Screening data will be reviewed to determine subject eligibility.
- Conditions
- Helicobacter Pylori, Safety, Efficacy
- Trial name
- NCT05276557
- Testing
- PyloPlus Urea Breath Test System, Stool Antigen Test
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ARJ Medical, Inc.
Helicobacter Pylori Infection
Knowledge, and Practice of Helicobacter Pylori Infection
Helicobacter Pylori infection is very common in Our community However, it may be misdiagnosed and treated from the start until the patient present with complications.
- Trial name
- NCT06628089
- Testing
- Questionnaire
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Gastric Cancer Screening, Prevention and Control
Helicobacter Pylori Infection and Gastric Diseases in Lao PDR: First Community-Wide Population-Based Study
This study aims to determine the regional prevalence of Helicobacter pylori infection, bacterial strain differences, and the prevalence of gastric cancer in two provinces of Laos, a multi-ethnic country where these factors may…
- Conditions
- Gastric Cancer Screening, Prevention and Control, Helicobacter Eradication, Helicobacter Infections
- Trial name
- NCT07340593
- Where
- Laos
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Zero Helicobacter IGAN Network
Irritable Bowel Syndrome
the Relationship Between Helicobacter Pylori Infection and Irritable Bowel Syndrome
Evaluating any possible relationship between irritable bowel syndrome occurrence and Helicobacter pylori infection
- Trial name
- NCT04847401
- Testing
- H. pylori stool antigen
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
H. Pylori Gastrointestinal Disease, H.Pylori Infection
CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Eradication
This study, titled CURE-H. Pylori, is a three-arm, parallel-group, open-label, randomized controlled trial designed to evaluate the effectiveness of Dexlansoprazole, Lansoprazole, and Vonoprazan in combination with Levofloxacin…
- Conditions
- H. Pylori Gastrointestinal Disease, H.Pylori Infection, H.Pylori Eradication Rate
- Trial name
- CURE-H Pylori (NCT07344506)
- Testing
- Arm 1: Dexlansoprazole + Levofloxacin-Based Triple Therapy, Arm 2: Lansoprazole + Levofloxacin-Based Triple Therapy, Arm 3: Vonoprazan + Levofloxacin-Based Triple Therapy
- Where
- Pakistan
- Volunteers
- 942 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Helicobacter Pylori Eradication, Adverse Reaction
Tegoprazan-Based Therapies for H. Pylori Eradication: A Randomized Controlled Trial
Current first-line Helicobacter pylori eradication protocols involve multidrug regimens comprising a proton pump inhibitor (PPI) or bismuth agent combined with dual antibiotics (e.g., clarithromycin, amoxicillin, quinolones…
- Trial name
- NCT06977841
- Testing
- Tegoprazan, Amoxicillin, Tetracycline
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital (Xiamen), Fudan University