Clinical trials: Helicobacter
Helicobacter Infection
Standard Triple Therapy vs Sequential Therapy in Treatment of H Pylori Infection
Traditionally, H pylori infection has been treated with conventional triple therapy. This includes amoxicillin, clarithromycin and a proton pump inhibitor all given daily for 10-14 days.
- Trial name
- NCT01723059
- Testing
- Standard Triple Therapy, Sequential Therapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Dallas VA Medical Center
Helicobacter Pylori
The Study on the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure
The patients who accepted the quadruple eradication program of the helicobacter pylori but failed to eradicate helicobacter pylori will be assessed the most suitable re-eradication time of helicobacter pylori.
- Trial name
- NCT04810793
- Testing
- Amoxicillin , Levofloxacin and Esomeprazole, Amoxicillin , Furazolidone and Esomeprazole, Tetracycline , Furazolidone and Esomeprazole
- Where
- China
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Shandong University
Helicobacter Pylori Infection Metabolic Dysfunction-Associated Fatty Liver Disease
Detection of Helicopacter Pylori in Patients With Metabolic Associated Fatty Liver Disease
Owing to the correlation between H.pylori and MAFLD, our study aims to search for H.pylori in every patient with MAFLD to aid in the management of MAFLD and improve quality of life for these patients by decreaseing morbidity and…
- Trial name
- HpyloriMAFLD (NCT07128147)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Migraine in Children
Association of Helicobacter Pylori Infection and Migraine
The study aims to assess the relation between migraine and H pylori infection in children and adolescent.
- Trial name
- NCT06558578
- Testing
- Helicobacter pylori antigen in stool
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Helicobacter Pylori Infection
Role of Vitamin D Supplementation as an Adjuvant Therapy inTreatment of Helicobacter Pylori in Children
To study the efficacy of vitamin D in conjunction with Helicobacter pylori treatment in children in eradication of helicobacter pylori.
- Trial name
- NCT05879237
- Testing
- Vitamin D3, Helicobacter pylori triple therapy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Minia University
Erosive Gastritis, Erosive Esophagitis(EE)
Bioequivalence Study to Compare Vonoprazan 20 mg Film Coated Tablets Versus Voquezna® 20 mg (Vonoprazan) Tablets
Randomized, Single Dose, Two-Way Crossover, Open Label bioequivalence study to compare Vonoprazan 20 mg Film Coated Tablets versus Voquezna® 20 mg (Vonoprazan) Tablets an oral administration to healthy adults under fasting…
- Conditions
- Erosive Gastritis, Erosive Esophagitis(EE), HELICOBACTER PYLORI INFECTIONS
- Trial name
- NCT07278349
- Testing
- Vonoprazan Tablets, VOQUEZNA® Tablets
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Hyperemesis Gravidarum
The Association of Helicobacter Pylori in the Pathogenesis of Hyperemesis Gravidarum in Pregnant Women
The purpose of this study to explore the association between Hyperemesis Gravidarum in pregnant women and Helicobacter pylori infection.
- Trial name
- AOHPIPOHGIPW (NCT02830321)
- Testing
- helicopacter pylori stool antigen test (CER TEST BIOTEC)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- rasha fawzy abd el kader
Helicobacter Pylori Infection, Post-Treatment
PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study
This is a multi-center, non-randomized, open label study. Subjects will be enrolled if they are deemed eligible given the inclusion criteria.
- Conditions
- Helicobacter Pylori Infection, Post-Treatment, Efficacy
- Trial name
- NCT05681689
- Testing
- PyloPlus UBT System, Histology, Rapid Urease Test
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- ARJ Medical, Inc.
Helicobacter Pylori Infection
Helicobacter Pylori Eradication Rates of Bismuth-containing Quadruple Therapy vs Modified Quadruple Therapy in Korea
South Korea has the highest incidence of gastric cancer worldwide and Helicobacter pylori infection is still prevalent. Clarithromycin-containing triple therapy is still the primary therapy approved by the Korean government.
- Trial name
- NCT03665428
- Testing
- PAMB treatment (modified quadruple therapy), PBMT treatment (bismuth-containing quadruple therapy)
- Where
- South Korea
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Helicobacter Pylori Eradication Rate
Modified Non-clarithromycin Triple Therapy in Eradicating Helicobacter Pylori
Helicobacter pylori (H. pylori) infects more than 50% of the population in the world(1), especially 47-66% in China.
- Trial name
- NCT02776371
- Testing
- Modified non-clarithromycin triple therapy, Sequential therapy
- Where
- China
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection
Non-bismuth quadruple therapies have been proposed as potential strategies in improving the efficacy of first-line treatments. The non-bismuth quadruple therapy in its concomitant variant consists of proton pump inhibitor…
- Trial name
- NCT04621487
- Testing
- Amoxicillin, Metronidazole, Clarithromycin
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Chronic Gastritis Caused by Helicobacter Pylori
Effect of Chicken Egg Antibody (IgY) on Patients With Chronic Gastritis
H. pylori positive patient volunteers that passed the selection criteria are recruited and divided into a test and a control group.
- Trial name
- NCT02721355
- Testing
- GastimunHP
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Immunology Research Institute in Gifu
Helicobacter Pylori Infection, Helicobacter Pylori Gastritis
Helicobacter Pylori Local Prevalence and Antibiotic Resistance
The clinical management of H. pylori infection depends essentially on two factors, prevalence and local resistance. In Germany, only limited data from rather small cohorts currently exist regarding both factors.
- Conditions
- Helicobacter Pylori Infection, Helicobacter Pylori Gastritis, Drug Resistant Bacterial Infection, Antibiotic Resistant Infection
- Trial name
- HelicoPTER (NCT05561504)
- Where
- Germany
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Human Microbiome
Effects of H.Pylori Eradication on Microbiome
The aim of this Project is, within the scope of industrial research, to evaluate the long term effects of H.pylori eradication on microbiome (gut microbiome, upper respiratory tract microbiome) and lasting adverse events.
- Trial name
- NCT03231332
- Testing
- Microbiome Diversity detection
- Where
- Latvia
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Caries, Periodontitis
The Effect of Miswak Chewing Sticks on the Oral Helicobacter Pylori Infection
To elucidate the relationship of chewing miswak sticks on the H. Pylori infection in the oral cavity.The study would be conducted at the Faculty of Dentistry, Kuwait University.
- Trial name
- Miswak (NCT02418520)
- Testing
- Miswak
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Helicobacter Pylori Infection, Acne Vulgaris
Prevalence of H.Pylori in Patients With Acne Vulgaris Acne Vulgaris
The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.
- Trial name
- NCT03411733
- Testing
- Blood and stool samples collection
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Helicobacter Infections
Levofloxacin Versus Clarithromycin Triple Therapy in First-Line Treatment for Helicobacter Pylori Eradication
Clarithromycin-based triple therapy containing a proton-pump inhibitor (PPI) twice daily, amoxicillin 1g twice daily, and clarithromycin 500 mg twice daily for 7 days is one of the standard firs-line therapy for Helicobacter…
- Trial name
- NCT00816140
- Testing
- Cravit based triple therapy, Klaricid based triple therapy
- Where
- Taiwan
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Inflammatory Bowel Diseases, Helicobacter Pylori Infection
The Relationship Between Helicobacter Pylori Infection and Inflammatory Bowel Diseases: A Real-life Observation
Numerous epidemiological studies have investigated the association between Helicobacter pylori (H. pylori) infection and inflammatory bowel disease (IBD) with various conflicting results.
- Trial name
- NCT04708405
- Testing
- Observation
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Helicobacter Pylori Infection
The Diagnostic Validity of the Urea Breath Test
1. To compare the diagnostic accuracy of the 13C-Urea breath test between using the citric acid as test meal and controlled group by endoscopic biopsy methods(histology, CLOtest and H. pylori culture). 2.
- Trial name
- NCT02359942
- Testing
- Citric acid
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital