Clinical trials: Helicobacter Infections
H Pylori Infection, H Pylori Gastritis
Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community- AIM 1
H. pylori is an infection of the stomach that can cause chronic gastritis, gastric cancer and peptic ulcer disease. The goal of this study is to screen people for this infection and offer treatment for those who test positive for…
- Conditions
- H Pylori Infection, H Pylori Gastritis, Gastric Cancer
- Trial name
- NCT07224035
- Testing
- PYTEST® 14C-Urea Breath Test, VOQUEZNA® Triple Pak®
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Miami
H.Pylori, Gastric Cancer
Helicobacter Pylori Infection and Gastric Disease in Bhutan: First Community-Wide, Population-Based Study
Background: Helicobacter pylori is a major risk factor for gastric cancer, yet in many developing countries, including Bhutan where gastric cancer incidence is high, access to screening and eradication is limited.
- Conditions
- H.Pylori, Gastric Cancer, H Pylori Eradication
- Trial name
- NCT07211880
- Testing
- Rabeprazole Sodium, Amoxicillin Hydrate, Clarithromycin, Upper gastrointestinal endoscopy for the H. pylori and serum pepsinogen positive individuals (high risk group of gastric cancer), Urea Breath Test for the prevalence of H pylori
- Where
- Bhutan
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- Zero Helicobacter IGAN Network
Helicobacter Pylori Infection
Factors Affecting Helicobacter Pylori Infection: Diet and Lifestyle Patterns
This cross-sectional observational study aims to determine the prevalence of Helicobacter pylori (H. pylori) infection among Information Technology (IT) professionals working in Hyderabad, India, and to identify dietary…
- Trial name
- NCT07837401
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Helicobacter Pylori Infection
Dysplasia Detection and Helicobacter Pylori Eradication
The investigators in the present study, aimed to assess the efficacy of both White-Light Endoscopy with High Resolution Endoscopy-Narrow-band imaging in the diagnosis of Premalignant Gastric Conditions, before and after…
- Trial name
- NCT03917836
- Testing
- endoscopy and histology
- Where
- Italy
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Helicobacter Pylori Infection
Efficacy and Safety of InSan Bamboo Salt on Improvement of Helicobacter Pylori Infection
The investigators performed a 4-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of InSan Bamboo Salt on improvement of Helicobacter pylori infection.
- Trial name
- NCT01735136
- Testing
- InSan Bamboo Salt
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Heliobacter Pylori Infection
Effect of Helicobacter Pylori on the Availability of Vitamin E and C
This study argues that H.pylori infection, by increasing the production of reactive oxygen species, increases the utilization of dietary antioxidants(Vit E and Vit C) that serve in quenching the free radicals, thus decreasing…
- Trial name
- NCT00303160
- Testing
- vitamin C & E supplements
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Gastric Cancer Screening, Prevention and Control
Helicobacter Pylori Infection and Gastric Diseases in Lao PDR: First Community-Wide Population-Based Study
This study aims to determine the regional prevalence of Helicobacter pylori infection, bacterial strain differences, and the prevalence of gastric cancer in two provinces of Laos, a multi-ethnic country where these factors may…
- Conditions
- Gastric Cancer Screening, Prevention and Control, Helicobacter Eradication, Helicobacter Infections
- Trial name
- NCT07340593
- Where
- Laos
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Zero Helicobacter IGAN Network
Gastric Cancer, Helicobacter Pylori Infection
Helicobacter Pylori Eradication for Gastric Cancer Prevention in the General Population
The aim of this study is to define the role of H. pylori eradication in the prevention of gastric cancer and its precursors in the context of a population-based endoscopic screening program.
- Trial name
- HELPER (NCT02112214)
- Testing
- 10-day bismuth-based quadruple therapy
- Where
- 11 sites in South Korea
- Volunteers
- 5,224 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Helicobacter Pylori Infection
Tegoprazan-containing Sequential for H. Pylori
As H. pylori eradication, the investigators prepared a randomized controlled clinical trial whether tegoprazan-containing 10-day sequential treatment was effective compared to conventional PPI-containing 10-day sequential…
- Trial name
- NCT06382493
- Testing
- Tegoprazan-containing sequential H. pylori eradication therapy, Esomeprazole-containing sequential H. pylori eradication therapy
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Pylori Infection, Antibiotic Resistant Infection
Optimal Tailored Treatment for H. Pylori Infection
The efficacy of the current standard triple therapy is at an unacceptably low level. Resistance to antibiotics is suspected to be the major cause of the low efficacy of standard triple therapy.
- Trial name
- NCT04462133
- Testing
- Dual-priming oligonucleotide-based multiplex polymerase chain reaction (DPO-PCR)
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Incheon St.Mary's Hospital
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
Measurement and Analysis of Gas Composition in Digestive Tract
The purpose of this study is to detect the concentration of various gases，including hydrogen, methane, hydrogen sulfide, nitric oxide in different parts of the digestive tract by a safe and direct method, and to establish a human…
- Conditions
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Functional Dyspepsia, Colorectal Neoplasms
- Trial name
- NCT05810805
- Testing
- gas component of digestive tract
- Where
- China
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Xiuli Zuo
Helicobacter Pylori
Helicobacter Pylori and Vonoprazan Dual Therapy
Our previous study included 119 Helicobacter pylori(H. pylori)-infected Chinese patients without previous eradication history who were randomized to low-or high-dose amoxicillin-vonoprazan regimens consisting of amoxicillin 1…
- Trial name
- NCT05649709
- Testing
- L-VA dual therapy, H-VA dual therapy
- Where
- China
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Nanchang University
Helicobacter Pylori Infection
Influencing Factors of Helicobacter Pylori Infection and Eradication Failure
Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases, the discovery and eradication of H.
- Trial name
- NCT05226819
- Testing
- PPI quadruple therapy
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Erosive Gastritis, Erosive Esophagitis(EE)
Bioequivalence Study to Compare Vonoprazan 20 mg Film Coated Tablets Versus Voquezna® 20 mg (Vonoprazan) Tablets
Randomized, Single Dose, Two-Way Crossover, Open Label bioequivalence study to compare Vonoprazan 20 mg Film Coated Tablets versus Voquezna® 20 mg (Vonoprazan) Tablets an oral administration to healthy adults under fasting…
- Conditions
- Erosive Gastritis, Erosive Esophagitis(EE), HELICOBACTER PYLORI INFECTIONS
- Trial name
- NCT07278349
- Testing
- Vonoprazan Tablets, VOQUEZNA® Tablets
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Helicobacter Pylori Infection, Susceptibility to
Helicobacter Pylori Infection Among Women With Recurrent Abortion of Unknown Cause
Helicobacter pylori (H. pylori) infection affects approximately one half of the world population and it is more prevalent in developing countries. This microorganism colonizes the stomach.
- Trial name
- NCT07293169
- Testing
- H pylori eradication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Kidney Diseases
Correlation Between Endoscopic Findings And Helicobacter Pylori Infection In Chronic Kidney Disease Patients
The aim of this study is to 1. Evaluate frequency of H. pylori infection in patients with CKD. 2. Description the gastroduodenal lesions found in patients with chronic kidney disease and correlate it to H.pylori infection.
- Trial name
- NCT05927766
- Testing
- esophagogastroduodenoscopy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Helicobacter Infection
The Efficacy of the 7 Days Tailored Therapy as the 1st Eradication of H. Pylori Infection
To compare the eradication success rate between 10-days sequential therapy and 7-days tailored therapy based on H. pylori culture and antimicrobial susceptibility testing.
- Trial name
- NCT02373280
- Testing
- 10 day sequential therapy (Esomeprazole, amoxicillin, clarithromycin, metronidazole), 7 day tailored PPI triple therapy (clarithromycin-containing triple therapy), 7 day moxifloxacin based triple therapy [Esomeprazole, Moxifloxacin, Amoxicillin]
- Where
- South Korea
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gastric (Stomach) Cancer, Helicobacter Infection
An Observational Study for Gastric Cancer in Carriers of High Risk Helicobacter Pylori
This study is intended to be a prospective observational cohort study. The incidence of gastric cancer and progression of gastric precancerous lesions will be compared between groups through prospective follow-up of a population…
- Trial name
- NCT06896370
- Testing
- observational study
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Helicobacter Pylori Infection
Sequential Versus Quadruple Therapy in the Second-line Treatment
Objectives: A recent randomized trial showed that 14-day sequential therapy containing high dose proton pump inhibitor was higher than 95% in the first line treatment.
- Trial name
- NCT03208426
- Testing
- Esomeprazole (S14), Esomeprazole (BQ10), Amoxicillin (ST14)
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital