Clinical trials: Helping Behavior
Respiratory Distress Syndrome, Newborn, Apnea of Prematurity
NIV-NAVA Versus Nasal Continuous Positive Airway Pressure (nCPAP) or Non Synchronized NIPPV
Mechanical respiratory support of preterm neonates with respiratory distress syndrome (RDS) and/or apnoea of prematurity (AOP) might be associated with adverse effects due to positive pressure (barotrauma), excessive gas delivery…
- Trial name
- Bio-NAVA (NCT02860325)
- Testing
- NIV-NAVA, Conventional
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Complejo Hospitalario Universitario Insular Materno Infantil
Lower Urinary Tract Symptoms, Adjustment Disorders
Lower Urinary Tract Symptoms in Women and Adjustment Disorder
Our hypothesis that the prevalence of AD in uro-gynecologic patients with LUTS who are seeking medical help for their condition is higher than that of the general population (indicated by high scores at the ADNM-20; score above…
- Trial name
- LUTS and AD (NCT03444740)
- Testing
- ICIQ-FLUTS, ADMN-20
- Volunteers
- 100 people
- Sponsor
- Basel Women's University Hospital
Stroke, Acute, Gait Disorders, Neurologic
The Effect of Powered-Knee Exoskeleton Assist on Stair Climbing in Acute CVA
Hypothesis/Specific Aims: The purpose of this research study is to determine if using an exoskeleton during stair climbing training will result in an improved ability to walk and climb stairs in individuals affected by recent…
- Trial name
- NCT03264235
- Testing
- Keeogo, Traditional Stair Training
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Shirley Ryan AbilityLab
Preventive Care
Impact of a Health Intervention on Some Indicators in the Care of Chronic Complex Patient (CCP).
The aim of this study is to assess the effectiveness of proactive and integrated healthcare program for chronic complex patients (CCP).
- Trial name
- CCP (NCT03091036)
- Testing
- Proactive healthcare intervention
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- María José del Olmo Rubio
Breast Cancer
Multi-Reader, Multi-Case, Cross-Over, Retrospective Study to Evaluate Effectiveness of Lunit INSIGHT DBT
This study aims to evaluate Effectiveness of Lunit INSIGHT DBT in the assistance of detection and diagnosis of breast cancer during 3D mammography interpretation
- Trial name
- NCT05716958
- Testing
- Digital Breast Tomosynthesis
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Lunit Inc.
Advanced Refractory Left Ventricular Heart Failure
HeartMate 3™ CE Mark Clinical Investigation Plan
The purpose of this clinical investigation is to evaluate the performance and safety of the HeartMate 3 Left Ventricular Assist System (HM3 LVAS) To support obtaining CE Mark for the HM3 LVAS in Europe, a multi-center clinical…
- Trial name
- HM3 CE Mark (NCT02170363)
- Testing
- Left Ventricular Assist System (LVAS)
- Where
- 10 sites in Australia, Austria and 4 more
- Volunteers
- 50 people
- Sponsor
- Abbott Medical Devices
Spinal Cord Injury, Tetraplegia
Abdominal Functional Electrical Stimulation (AFES) to Assist Ventilator Weaning in Tetraplegia
Compromised respiratory function as a result of tetraplegia leads to many tetraplegics requiring mechanical ventilation during the acute phase of injury.
- Trial name
- NCT02200393
- Testing
- Abdominal FES
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Glasgow
Endoscopy, Communication
Impact of Digital Communication Assist Tools in Endoscopic Team Communication During COVID-19
Team work is highly challenged by the COVID-19 pandemic. Necessary protective equipment as FFP-mask and face shields impair communication significantly.Objective of the study is to evalaute the impact of digital enhanced…
- Trial name
- EndoCom (NCT04680858)
- Testing
- DECT
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- University of Ulm
Emphysema, Acute Respiratory Distress Syndrome
Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure
A new artificial lung device has been developed that potentially provides added support to mechanical ventilation for severely damaged lungs.
- Conditions
- Emphysema, Acute Respiratory Distress Syndrome, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT00288964
- Testing
- Hattler Respiratory Assist Catheter
- Where
- United Kingdom
- Sponsor
- Alung Technologies
Heart Failure
Evaluation of Myocardial Improvement in Patients Supported by Ventricular Assist Device Under Optimal Pharmacological Therapy
Cardiac function may improve in patients with end-stage heart failure who receive long-term support with ventricular assist devices (VAD).
- Trial name
- NCT00402376
- Testing
- Pravastatin, Carvedilol, Perindopril, Biventricular assist device (Thoratec paracorporeal assist device)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
High-Risk Percutaneous Coronary Intervention (High-risk PCI), Left Ventricular Assist Devices
Interventional Ventricular Assist System for PCI in CHIP Patients
In patients with complex coronary artery disease (CAD), determining the optimal revascularization strategy (percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) remains a challenge.
- Trial name
- REC-CHIPMCS (NCT06373120)
- Testing
- Microaxial flow pump, VA-ECMO
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Shenzhen Core Medical Technology CO.,LTD.
High-risk Percutaneous Coronary Intervention
Magenta Elevate™ EFS in High-Risk PCI Patients
The Elevate™ EFS study is designed to evaluate the safety and feasibility of the Magenta Elevate™ percutaneous Left Ventricular Assist Device (pLVAD) System in patients undergoing non-emergent, high-risk percutaneous coronary…
- Trial name
- NCT05727059
- Testing
- The Elevate™ System
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Magenta Medical Ltd.
Infertility, Reproductive Techniques, Assisted
In Vitro Maturation of Human Eggs
Because a large proportion of the embryo's quality is dependent upon the egg, this investigation focuses on treatment of the oocyte during in vitro maturation (IVM).
- Trial name
- IVM (NCT02516462)
- Testing
- IVM media, Follicle Stimulating Hormone (FSH)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Foundation for Fertility Research
Advanced Heart Failure
Post Market Surveillance of the HeartMate 3 Left Ventricular Assist System in Korea
The Korea HM3 PMS is a prospective, single arm, open-label, multi-center, post market surveillance is designed to evaluate clinical and functional outcomes with the HM3 LVAS as a treatment for advanced heart failure.
- Trial name
- NCT04915924
- Testing
- HeartMate 3™ left ventricular assist system (HM3 LVAS)
- Where
- 22 sites in South Korea
- Volunteers
- 358 people
- Sponsor
- Abbott Medical Devices
Lung Cancer, Artificial Intelligence (AI)
The Impact of AI Assistance on Radiologist Performance and Healthcare Costs in LDCT-Based Lung Cancer Screening
AI diagnostic systems show great promise for improving lung cancer screening in community healthcare settings. While not originally designed for primary care, these tools demonstrate capabilities in nodule detection and workflow…
- Conditions
- Lung Cancer, Artificial Intelligence (AI), Randomized Controlled Trial
- Trial name
- NCT06988579
- Testing
- AI
- Where
- China
- Volunteers
- 7,294 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Postoperative Patients
Diaphragmatic Activity During Weaning With NAVA, a Pilot Study (NAVA: Neurally Adjusted Ventilatory Assist)
The purpose of this study is to describe the diaphragm electromyographic activity (Edi) in healthy lung patients due to obtain a reference to guide the weaning in those patients
- Trial name
- NAVA (NCT03027713)
- Testing
- weaning protocol
- Volunteers
- 40 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Difficult Vein Access, Emergency Department Patients
Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses
Obtaining intravenous (IV) access is one of the most common procedures performed in the emergency department (ED). IV access is necessary for many aspects of patient care, including blood tests, administration of medications and…
- Conditions
- Difficult Vein Access, Emergency Department Patients, Nurses Role, Midline Catheter
- Trial name
- SUMMIT (NCT07779317)
- Testing
- Ultrasound-Guided Single-Lumen Midline Catheter, Ultrasound-Guided Long Peripheral Intravenous Catheter
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Albany Medical College
Respiratory Failure
NAVA Versus BiPAP Non-Invasive Respiratory Support in Infants Following Congenital Heart Surgery
Pediatric patients often require prolonged mechanical ventilation after cardiac surgery which comes with many undesirable effects.
- Trial name
- NAVA (NCT03180385)
- Testing
- Neurally-Adusted Ventilatory Assist (NAVA), Biphasic Positive Airway Pressure Support (BiPAP)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Healthy Volunteers, Robotic Exoskeleton
Effects of Hip-Assist Exoskeleton Torque on Gait Parameters
This study aims to evaluate the impact of assistive torque from a hip-assist exoskeleton on gait patterns in healthy adults. The investigators will analyze how different torque settings affect spatiotemporal parameters, joint…
- Conditions
- Healthy Volunteers, Robotic Exoskeleton, Wearable Devices, Assistive Devices
- Trial name
- NCT07450989
- Testing
- ANGEL SUIT H10 (Hip-assist exoskeleton)
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Left Ventricular Assist Device, End-stage Heart Failure
Preoperative Nutritional Optimization and Physical Exercise for Patients Scheduled for Elective Implantation for a Left-Ventricular Assist Device
This is a pilot, randomized, multicenter interventional trial of a combined preoperative oral nutritional support (ONS) and physical exercise therapy in patients planned for elective implantation of a left-ventricular assist…
- Conditions
- Left Ventricular Assist Device, End-stage Heart Failure, Cardiac Surgery
- Trial name
- PROPER-LVAD (NCT04205760)
- Testing
- Nutrition + exercise
- Where
- 5 sites in Germany
- Volunteers
- 40 people
- Sponsor
- RWTH Aachen University