Clinical trials: Helping Behavior
Psychotic Episode
Effect of Experience Sharing and Mutual Assistance on Insight and Recovery During the First Psychotic Episode
Controlled, prospective, qualitative and quantitative trial. The goal of this trial is to evaluate the mutual assistance early intervention device efficacy and its impact on insight and personal recovery of participants living…
- Trial name
- DIPEM (NCT06263933)
- Testing
- Insight Scale, Semi-directional interviews, routine care
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Cardiovascular Diseases, Heart Diseases
Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH)
To conduct a randomized, unblinded clinical trial comparing the left ventricular assist device (LVAD) with maximum medical management in patients with end-stage heart failure who were not candidates for heart transplantation.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Failure, Heart Failure, Congestive
- Trial name
- NCT00000607
- Testing
- Left ventricular assist device, Optimal medical therapy
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Columbia University
Behavior, Health
Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters
A substantial portion of the United States population remains overdue for key screenings, despite availability and insurance coverage of preventive health services.
- Trial name
- PROACTIVE (NCT07636187)
- Testing
- Pre-visit and post-visit patient messaging, Default pended order, EHR communication
- Where
- United States
- Volunteers
- 16,416 people
- Sponsor
- University of Pennsylvania
Heart Failure
Exercise Training in Patients With Left Ventricular Assist Device
The objective of the study is to test whether 12 weeks of structured supervised exercise training on top of usual care improves functional capacity in patients with end-stage heart failure with continuous flow left ventricular…
- Trial name
- Ex-VAD (NCT03369938)
- Testing
- exercise training intervention
- Where
- 5 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Charite University, Berlin, Germany
Heart Failure.
The Increase Study. Effect of Incremental Versus Fixed Pump on Peak Oxygen Consumption in Heart Failure Patients Supported With a Continuous Flow Left Venticular Assist Device
The purpose of the study is to examine the relationship between working capacity (peak oxygen consumption) and pump speed of continuous flow left ventricular assist devices (CF-LVADs)in heart failure patients.
- Trial name
- NCT01698398
- Testing
- Incremental pump speed of CF-LVAD.
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Amputation Wound, Peripheral Arterial Disease
Wound Imaging Study to Gather Clinical References for a Device to Assist Selecting Level-of-amputation in PAD Patients
This is a proof-of-concept study to collect images to train a CADe algorithm to predict the correct level of amputation in individuals scheduled for amputation secondary to PAD.
- Trial name
- WISCR (NCT03611361)
- Testing
- SpectralMD DeepView Wound Imaging System 2.0
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- SpectralMD
Extracorporeal Membrane Oxygenation Complication
Estimation of Glomerular Filtration Flow in Patients of Resuscitation Under Extra-bodily Assistance
The aim of the study will be to evaluate the quality of the GFR estimate of the two estimation equations (CKD-EPI and Cockcroft's formula) against the measured clearance of creatinine, which can be performed routinely in…
- Trial name
- CREA-ECMO (NCT03525483)
- Testing
- Ultrasound for renal resistivity index measurement
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Acute Viral Bronchiolitis
NAVA in Infants With Acute Viral Bronchiolitis: A Feasibility Study
This exploratory intervention feasibility study aims to evaluate the use of a novel mode of ventilation known as Neurally adjusted ventilatory assist (NAVA) in infants with acute viral bronchiolitis. The main aims are: 1.
- Trial name
- NCT05899894
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Driveline Infection
Incidence and Management of Driveline Infection in Patients with CH-VAD
The goal of this observational study is to learn about the incidence of the Driveline Infection of a novel full-magnetically levitated left ventricular assist device with a new design of driveline.
- Trial name
- NCT06878456
- Where
- China
- Volunteers
- 181 people
- Sponsor
- China National Center for Cardiovascular Diseases
Submucosal Tumor of Gastrointestinal Tract
Hydrogel Injection to Assist Endoscopic Submucosal Dissection
The aim of the investigators' study is to evaluate the mucosa-elevating capacity and clinical safety of Sodium Alginate (SA) mixed with Calcium Lactate in assisting Endoscopic Submucosal Dissection/Endoscopic Mucosal Resection.
- Trial name
- NCT03321396
- Testing
- sodium alginate mixed with calcium lactate
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Cheng-Kung University Hospital
Bronchiolitis
Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis
This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy…
- Trial name
- NCT06053684
- Testing
- Standard Non-Invasive Mechanical Servo Ventilation, Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Montefiore Medical Center
Diabetes, HIV/AIDS
Food Assistance, Diabetes, and HIV
Diabetes prevalence is increasing among people living with HIV (PLWH), yet blood glucose control is less successful in this population who are also often food insecure. Food assistance programs often provide nutrient-poor foods.
- Conditions
- Diabetes, HIV/AIDS, FOOD SECURITY
- Trial name
- BFED (NCT04045184)
- Testing
- Food assistance
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Surgical Training
Laparoscopic Training With and Without Robotic Assistance for Surgical Internes: a Randomized Study
The primary objective of this study is to compare two groups of gynecologic/urologic/visceral internes in terms of the time required to perform a laparoscopic surgical intervention (nephrectomy) on an animal model (pig).
- Trial name
- LAPRA (NCT02888158)
- Testing
- Robotic assistance, Pelvic Trainer
- Where
- 2 sites in France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Vaginal Atrophy, Atrophic Vaginitis
ASSIST-VLA: Assessment of Symptom-Specific Improvement in Diagnosed Vaginal Atrophy Following Laser Therapy
Vaginal atrophy patients receiving vaginal laser therapy will be treated with daily 7-0940® following a laser session to evaluate the safety and efficacy of the product as an adjunct treatment.
- Conditions
- Vaginal Atrophy, Atrophic Vaginitis, Genitourinary Syndrome of Menopause (GSM)
- Trial name
- ASSIST-VLA (NCT07346287)
- Testing
- 7-940
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stratpharma AG
Advanced Heart Failure, Left Ventricular Assist Device Implantation
GDF-15 and Early Outcomes After LVAD Implantation
This observational study aims to investigate the association between preoperative GDF-15 levels and early postoperative outcomes in patients undergoing left ventricular assist device (LVAD) implantation.
- Trial name
- LVAD-GDF15 (NCT07497308)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Akdeniz University
Heart Failure, End-stage Disease
Proactive Palliative Care for Patients With Ventricular Assist Devices (VAD) and Their Families
The primary aim of the study is to provide "proof of concept" to demonstrate that patients with Ventricular Assist Devices (VADs) and caregivers are willing to be enrolled in a randomized trial of palliative care and that such a…
- Trial name
- NCT01427634
- Testing
- Palliative Care, Usual Care
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Idiopathic Axonal Polyneuropathy
A Study to Determine if Levetiracetam Will Assist Those Suffering From Chronic Idiopathic Axonal Polyneuropathy.
Considering the mechanisms of action which provide efficacy in epilepsy, it is hypothesized that treatment with levetiracetam will reduce the neuronal excitability involved in neuropathic pain associated with CIAP.
- Trial name
- NCT00156689
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University
Pulmonary Arterial Hypertension
Nitric Oxide, GeNO Nitrosyl Delivery System
The primary aim of the study is to evaluate the safety, tolerability and device performance of the GeNO nitrosyl delivery system during RHC.
- Trial name
- NCT01165047
- Testing
- Nitric Oxide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Diagnosis, Diabetic Retinopathy
Efficacy of Using Large Language Model to Assist in Diabetic Retinopathy Detection
With the increase in population and the rising prevalence of various diseases, the workload of disease diagnosis has sharply increased.
- Trial name
- NCT05231174
- Testing
- A self-evlaution tool based on Large Language Model
- Where
- China
- Volunteers
- 535 people
- Sponsor
- Sun Yat-sen University
Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome
Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD
Cardiovascular disease is the leading cause of mortality in the US, accounting for 45% of all deaths. Chronic Heart Failure (CHF) is now understood to be a multi-system disease process involving not only the cardiovascular system…
- Trial name
- NEUTRALIZE-CRS (NCT03836482)
- Testing
- Selective Cytopheretic Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- SeaStar Medical
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