Clinical trials: Helping Behavior
Phosphodiesterase Inhibitor Adverse Reaction, Right-Sided Heart Failure
Phosphodiesterase-5-inhibitors for Right Heart Failure After Left Ventricular Assist Device Implantation
Refractory right heart failure is common during the postoperative period after left ventricular assist device implantation. Oral phosphodiesterase-5 inhibitors are oft initiated in order to facilitate weaning from the intravenous…
- Trial name
- PIVAD (NCT04117659)
- Testing
- withdrawal of oral medication (phosphodiesterase-5 inhibitor) in pretreated patients
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- University Hospital, Essen
Left Ventricular Assist Device, Percutaneous Lead Management
Thoratec's Reduce Driveline Trauma Through Stabilization and Exit Site Management Study
The purpose of this study is to evaluate the feasibility of a Percutaneous Lead Management Kit for HeartMate II driveline stabilization and exit site management.
- Trial name
- RESIST (NCT01485666)
- Testing
- Percutaneous Lead Management Kit
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Abbott Medical Devices
Acute Liver Failure, Acute Liver Injury, Drug Induced
miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial
The clinical trial will assess the safety of miroliverELAP for the treatment of acute liver failure, severe acute alcohol-associated hepatitis, or acute on chronic liver failure.
- Conditions
- Acute Liver Failure, Acute Liver Injury, Drug Induced, Acute on Chronic Liver Failure (ACLF), Acute Alcoholic Hepatitis
- Trial name
- NCT06285253
- Testing
- miroliverELAP treatment
- Where
- 8 sites in United States
- Volunteers
- 10 people
- Sponsor
- Miromatrix Medical Inc.
Heart Failure, Left-Sided, Heart Failure, Right-Sided
Central and Cerebral Circulation in Early Stages After LVAD Implantation
This trial will evaluate patients with a mechanical Left Ventricular Assist Device (LVAD) in early stages after surgical implantation.
- Trial name
- ECOH3 (NCT03087669)
- Testing
- LVAD flow velocity setting-Rounds per Minute(RPM) on HeartMate III®, MAP intervention using Noradrenalin
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Sahlgrenska University Hospital
Stroke
Feasibility Study of Caregiver-Assist Strategy Training
The goal of this study is to examine the feasibility of delivering an innovative intervention, caregiver-assisted strategy training (CaST), targeting enhancing activity functions in community-dwelling adults after stroke.
- Trial name
- NCT06741475
- Testing
- Caregiver-Assist Strategy Training, Education
- Where
- 3 sites in Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Heart Failure
Identifying and Facilitating Ventricular Recovery on Mechanical Support
Heart failure is a progressive disorder in which the weakened heart is not able to efficiently pump blood throughout the body. When the body's cells do not receive enough blood, this can result in fatigue, shortness of breath…
- Trial name
- RECOVER (NCT00687856)
- Testing
- Echocardiogram (echo)
- Where
- 5 sites in United States
- Volunteers
- 211 people
- Sponsor
- University of Pittsburgh
Laryngopharyngeal Reflux
Assessing the Impacts of a UESAD on Laryngeal Symptoms and Salivary Pepsin
It is postulated that the incompetence of the upper esophageal sphincter (UES) to restrict passage of esophageal refluxate is fundamental to the development of LPR.
- Trial name
- NCT02552966
- Testing
- UESAD
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Child Externalizing Behavior
Technology-Enhanced Helping the Noncompliant Child
This study aimed to examine if technology could enhance the treatment engagement and outcomes of low income parents of 3 to 8 children with externalizing problems.
- Trial name
- TE-HNC (NCT01367847)
- Testing
- Helping the Noncompliant Child (HNC), Technology-Enhanced Helping the Noncompliant Child (TE-HNC)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Feasibility, Anxiety
Feasibility Study: Being a Parent - Helping Your Child With Fears and Worries
Emotional disorders are among the most common childhood mental health difficulties. The majority of adult emotional disorders begin before age 14 years.
- Conditions
- Feasibility, Anxiety, Empowerment, Peer Influence
- Trial name
- BAPHYC (NCT05790343)
- Testing
- BAPHYC
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Surgery, Bariatric Surgery Candidate
Magnetic System in Bariatric and General Surgery
Magnetic devices have been successfully used in bariatric surgery. To the date the only reported use of the magnet was for liver retraction.
- Trial name
- NCT04944810
- Testing
- Magnetic Gastric Bypass, Magnetic Sleeve Gastrectomy, Revisional Bariatric Surgery
- Where
- Venezuela
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Unidad Internacional de Cirugia Bariatrica y Metabolica
Patient Operated on From a Vestibular Schwannoma With a Middle Ear Exclusion
Robot Based Tympanic Tube Placement
Middle ear surgery is performed in a deep workspace through a narrow approach to the tympanic cavity, either by the external auditory canal, or by drilling the temporal bone.
- Trial name
- ROBOTOL (NCT03569943)
- Testing
- Robot Based Transtympanic drain placement
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Lymphoid Leukemia
Evaluation of the Ambulatory Medical Assistance Nurse Program in Chronic Lymphocytic Leukemia
The emergence of targeted therapy (ibrutinib, venetoclax, acalabrutinib) has revolutionized the management practices of chronic lymphoid leukemia due to their effectiveness.
- Trial name
- THEMIS (NCT05350826)
- Testing
- Ambulatory medical assistance
- Where
- 16 sites in France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Toulouse
Lower Limb Amputation
KinetiGait- Analysis of Depth Camera to Assist Gait Analysis for Unilateral Transtibial/Transfemoral Amputees
This is a feasibility study about implementing and using the KinetiGait gait analysis system in clinical practice to enhance the rehabilitation of service members with lower limb disfunction.
- Trial name
- NCT04431817
- Testing
- KinetiGait
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Colon Polyp, Colon Neoplasm
A Clinical Study To Measure The Effect Of Use Of Artificial Intelligence (AI) Enabled Computer Aided Detection (CADe) Assistance Software In Detecting Colon Polyps During Standard Colonoscopy Procedures
EndoVigilant software device augments existing colonoscopy procedure video in real-time by highlighting colon polyps and mucosal abnormalities.
- Conditions
- Colon Polyp, Colon Neoplasm, Colon Adenoma
- Trial name
- ColonCADe (NCT04555135)
- Testing
- EndoVigilant Software
- Where
- 4 sites in United States
- Volunteers
- 769 people
- Sponsor
- EndoVigilant Inc
Acute Respiratory Failure
NAVASET: Nava Level Titration Using Comfort Scales
Determining the optimal Neurally Adjusted Ventilatory Assist (NAVA) level remains challenging, and several methods have been suggested. However none of them seems easily utilisable.
- Trial name
- NCT02133443
- Testing
- PSV - pressure support ventilation, Neurally Adjusted Ventilatory Assist
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Infertility
Efficacy and Safety Study of a Single Injection of SCH 900962 Versus Daily recFSH Injections in Women Undergoing Controlled Ovarian Stimulation (Study P06029)
The purpose of this study is to show that a single injection of SCH 900962/MK-8962 is non-inferior to daily injections of recombinant follicle-stimulating hormone (recFSH) during the first week of ovarian stimulation in terms of…
- Trial name
- PURSUE (NCT01144416)
- Testing
- SCH 900962 / Corifollitropin alfa / Org 36286, RecFSH / follitropin beta
- Volunteers
- 1,424 people
- Sponsor
- Organon and Co
Reproductive Techniques, Assisted
Early Follicular Phase vs Lutheal Phase Ovarian Stimulation in Bologna Criteria IVF/ICSI Cycles (LUTEAL Trial)
Exploratory, prospective, randomized, comparative, open trial with control group treated to assess the efficacy of follicular phase ovarian stimulation compared to lutheal phase ovarian stimulation in women with Bologna criteria…
- Trial name
- LUTEAL (NCT02625532)
- Testing
- Follicular phase, Luteal phase
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Acute Respiratory Distress Syndrome
Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS
Neurally-Adjusted Ventilatory Assist (NAVA) is a ventilatory mode that uses the electrical activity of the diaphragm to control the mechanical ventilator, offering inspiratory assistance in proportion to respiratory effort to…
- Trial name
- NCT01519258
- Testing
- Pressure Support ventilation, NAVA
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Left Ventricular Assist Device
Exercise Tolerance in Patients With Implanted Left Ventricular Assist Device
To evaluate the concept of dynamic pump speed optimization based on the echocardiographic assessment of aortic valve opening during cardiopulmonary exercise test.
- Trial name
- NCT05063006
- Testing
- Cardiopulmonary exercise tests with maintained baseline optimal pump speed settings., Cardiopulmonary exercise test with gradually increased pump speed depending on live echocardiographic imaging.
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Karol Wierzbicki
Smoking
Helping Ethnic Minority in Hong Kong to Quit Smoking by Understanding Their Knowledge, Attitude and Behavior Related to Smoking
This study aims at understanding the needs and concerns of the ethnic minority in Hong Kong, including their behavior, attitudes, and experiences related to smoking and smoking cessation.
- Trial name
- NCT04025333
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
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