Clinical trials: Helping Behavior
Heart Failure
Assessment of Safety and Accuracy of the Microtech System in Patients Undergoing Left Ventricular Assist Device Implantation
The Microtech-LVAD study is designed as a prospective, single arm, multi-center early feasibility study. Approximately 15 patients will be enrolled in the study.
- Trial name
- Microtech-LVAD (NCT06682910)
- Testing
- Microtech sensor pressure
- Where
- 2 sites in United States, Israel
- Volunteers
- 15 people
- Sponsor
- Microtech Medical Technologies, Ltd
Ventricular Assist Device, Advanced Heart Failure
Multi-Site Feasibility Testing of the Ventricular Assist Device Anticipatory Guidance Tool
There are a variety of educational documents available to help in a participant's decision for VAD implant, however there is little information available to potential participants to help understand areas of satisfaction and…
- Conditions
- Ventricular Assist Device, Advanced Heart Failure, Anticipatory Guidance
- Trial name
- NCT06823583
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Bryan Heart
Congenital Heart Surgery, Cardiopulmonary Bypass
Use of Phenoxybenzamine [PBZ] IV to Assist High Flow Low Pressure Perfusion [HFLPP] on Cardio-pulmonary Bypass
Cardiopulmonary bypass [CPB] in small size bodies can result in decreased peripheral perfusion. This results in anaerobic metabolism as evidenced by lactic acidosis.
- Trial name
- NCT00620945
- Testing
- Phenoxybenzamine
- Volunteers
- 87 people
- Sponsor
- The Cleveland Clinic
Heart-Assist Devices, Heart Failure
Individual Blood Pressure Optimization Based on Cerebral Autoregulation After Implantation of Continuous-flow LVAD
This study will collect retrospective and prospective clinical data regarding the Principal Investigator's patient population to allow for data analysis seeking basic trends and to prepare academic reports, including journal…
- Trial name
- NIRS (NCT03093012)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Baylor College of Medicine
Constipation
Use of a Squatting Assist Device in Patients With Constipation
Constipation is a very common problem. Western style toilets that are nearly universal in the United States require the person to sit on the toilet.
- Trial name
- NCT02877394
- Testing
- Squatting Assist Device
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Mayo Clinic
End Stage Heart Failure
Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation
Continuous-flow left ventricular assist devices (LVAD) move blood from the left ventricle (the largest chamber of the heart) to the aorta (the body's main artery) to help the heart better meet the needs of the body and to improve…
- Trial name
- NCT03356353
- Testing
- Sildenafil Citrate
- Where
- 4 sites in Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Cardiovascular Diseases, Heart Diseases
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Failure
- Trial name
- INNOVATE (NCT06310031)
- Testing
- BrioVAD System, HeartMate 3
- Where
- 47 sites in United States
- Volunteers
- 780 people
- Sponsor
- BrioHealth Solutions, Inc.
AIDS and Infections, HIV Prevention
The BeT Study Intervention to Reduce Disparities in HIV Prevention and Care
Stigma prevents young transgender women from having access to HIV prevention and care services, despite the fact that these services are freely accessible to all Brazilians in the Unified Health System (ie, SUS).
- Conditions
- AIDS and Infections, HIV Prevention, Stigma, Social, Hiv
- Trial name
- BET (NCT05299645)
- Testing
- Interview
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Feasibility Study of the Intravascular Ventricular Assist System (iVAS)
The purpose of this feasibility study is to assess the preliminary safety and clinical performance of the intravascular ventricular assist system (iVAS).
- Trial name
- NCT02645539
- Testing
- intravascular ventricular assist system (iVAS)
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- NuPulseCV
Heart Failure, Chronic Systolic Heart Failure
SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device)
The purpose of this clinical trial is to see if a new device (SCD) is safe and if it can reduce damage to the kidney enough to allow medications to work to improve heart and kidney function for use in patients that have moderate…
- Conditions
- Heart Failure, Chronic Systolic Heart Failure, Renal Failure, Cardiorenal Syndrome
- Trial name
- NCT04589065
- Testing
- Selective Cytopheretic Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lenar Yessayan
Continous Flow Left Ventricular Device
Impact of Hemodynamic Ramp Test-Guided HVAD RPM and Medication Adjustments on Exercise Tolerance and Quality of Life
The main purpose of this study is to compare Echo-guided testing to the Hemodynamic-Echo Ramp Tests to determine which method of testing provides better information for adjusting pump speed and medical treatment for Left…
- Trial name
- Ramp-it-Up (NCT03021239)
- Testing
- Echo Guided Testing, Hemodynamic-Echo Ramp Testing -
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Diabetes, Type 1
Edmonton Automated Sugar Intelligence - Intelligent Diabetes Management, EASI-IDM, App Program to Assist Diabetes Care
A closed loop system for diabetes care utilizing an insulin pump, continuous glucose sensing and appropriate mathematical modelling to guide insulin dosing is a goal for those with Type 1 diabetes.
- Trial name
- EASI-IDM (NCT02214719)
- Testing
- EASI-IDM use
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University of Alberta
Vascular Access
Investigating the Utility of Augmented Reality Assistance for Ultrasound-Guided Vascular Access
This study will investigate the benefits of augmented reality assistance on ultrasound-guided vascular access. Using the Microsoft HoloLens 2 headset, the investigators will study the benefits of augmented reality technology as a…
- Trial name
- NCT07208071
- Testing
- Augmented reality headset use
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Alabama at Birmingham
Acute Liver Failure, Acute Liver Injury, Drug Induced
miroliverELAP® for the Treatment of Acute Liver Failure: A Phase 1 Trial
The clinical trial will assess the safety of miroliverELAP for the treatment of acute liver failure, severe acute alcohol-associated hepatitis, or acute on chronic liver failure.
- Conditions
- Acute Liver Failure, Acute Liver Injury, Drug Induced, Acute on Chronic Liver Failure (ACLF), Acute Alcoholic Hepatitis
- Trial name
- NCT06285253
- Testing
- miroliverELAP treatment
- Where
- 8 sites in United States
- Volunteers
- 10 people
- Sponsor
- Miromatrix Medical Inc.
Parkinson
Clinical Investigation of NMS Assist
Parkinson's can cause a wide range of non-motor symptoms (NMS), including pain and problems with mental health, memory and sleep. These affect the quality of life of people with Parkinson's (PwP) and their care partners (CP).
- Trial name
- NCT05414071
- Testing
- NMS Assist
- Sponsor
- University of Plymouth
ERCP Training, Biliary Tract Diseases
Effect of Off-site Assistance on Success Rate of Selective Cannulation During hands-on ERCP Training
Endoscopic retrograde cholangiopancreatography (ERCP) is a technically challenging procedure. It takes time to learn the basic skills and need at least 180 - 200 cases for trainees to achieve competency in ERCP.
- Conditions
- ERCP Training, Biliary Tract Diseases, Pancreatic Diseases
- Trial name
- NCT05249400
- Testing
- Off-site assistance
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Amyloid Cardiomyopathy, Transthyretin Amyloid Cardiomyopathy
Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis
The goal of this study is to develop an algorithm using artificial intelligence (AI) to assist identification of potential ATTR-CM cases using routine transthoracic echocardiography.
- Conditions
- Amyloid Cardiomyopathy, Transthyretin Amyloid Cardiomyopathy, Transthyretin Cardiac Amyloidosis
- Trial name
- AI-ATTR-ECHO (NCT06328075)
- Testing
- non interventional study
- Where
- France
- Volunteers
- 15,000 people
- Sponsor
- Algalarrondo Vincent
Adenopathy, Uterine Fibroids
A Clinical Study on the Feasibility and Safety of Abdominal Endoscopic Single-port Surgery System to Assist Gynecological Day Surgery
In this study, a prospective study is used to select patients who will undergo intra-abdominal endoscopic single-port surgery system for benign gynecological diseases from February 2025 to December 2026 in the Second Affiliated…
- Conditions
- Adenopathy, Uterine Fibroids, Ovarian Cysts, Adnexal Mass
- Trial name
- NCT06828419
- Testing
- Domestic single-port laparoscopic surgery system
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Healthcare-Associated Infections
Understanding and Addressing Variations in HAIs After Durable Ventricular Assist Device Therapy
Substantial center variability exists in healthcare-associated infection (HAI) rates following durable ventricular assist device (VAD) implantation for patients with advanced heart failure.
- Trial name
- NCT03749434
- Where
- United States
- Volunteers
- 34,958 people
- Sponsor
- University of Michigan
Drug Use
The Impact of Alternative Social Assistance Disbursement on Drug-related Harm
This study evaluates whether altering the timing and frequency of social assistance disbursement reduces drug related-harms that increase on the days surrounding monthly synchronized government social assistance cheque issue.
- Trial name
- TASA (NCT02457949)
- Testing
- Non-synchronized social assistance receipt, cheque divided into two equal disbursements
- Where
- Canada
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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