Clinical trials: Helping Behavior
Chronic Respiratory Failure
Assist Control Versus Pressure Support Modes for Domiciliary Noninvasive Ventilation in Chronic Respiratory Failure
Noninvasive ventilation is a therapeutic option in some patients with chronic respiratory failure. Patients usually ventilate during nightime with a domiciliary ventilator either in assist control or in pressure support mode.
- Trial name
- NCT00189527
- Testing
- respiratory settings
- Volunteers
- 100 people
- Sponsor
- Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Dyspnea
Impact of Proportional Assisted Ventilation on Dyspnea and Asynchrony in Mechanically Ventilated Patients
Rational. The mismatch between the activity of the respiratory muscles and the assistance delivered by the ventilator results in patient-ventilator disharmony, which is commonly observed in ICU patients and is associated with…
- Trial name
- DYS-PAV (NCT02801994)
- Testing
- PAV, Puritan Bennett 980 ventilator
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Laryngeal Neoplasms
Surgical Treatment of Early Stage Glotto-supraglottic Laryngeal Cancer Via Transoral Resection With Robotic Assistance
The main objective of this study is to determine the rate of healthy surgical margins after tumor resection in transoral robot-assisted surgery for glottic and/or supraglottic early stage (T1-T2) laryngeal cancer.
- Trial name
- NCT01257633
- Testing
- Transoral robot-assisted tumor resection using the da Vinci robot
- Where
- 3 sites in France
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Covid19- Coronavirus- Sars-cov-2
Implementation of a Respiratory Physiotherapy Program in Post COVID-19 Patients Through Tele-assistance
The objective of this research project is to scientifically evidence a pulmonary rehabilitation program that was initiated altruistically during the confinement of those patients who had suffered from COVID-19, through an online…
- Trial name
- NCT04678700
- Testing
- Chest physiotherapy post-covid19
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- European University of Madrid
Incomplete Spinal Cord Injury, Muscular Dystrophy
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Background: Cerebral palsy (CP) is the most common motor disorder in children. CP often causes crouch gait, an abnormal way of walking. Knee crouch has many causes, so no single device or approach works best for everybody.
- Conditions
- Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
- Trial name
- NCT01961557
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Gastrointestinal Bleeding, Complication of Internal Device
Occult Gastrointestinal Bleeding in Non-pulsatile Left Ventricular Assist Device(VAD)Patients
The purpose of this study is to estimate the proportion of Ventricular Assist Device (VAD) patients with abnormal gastrointestinal bleeding as assessed by HemoQuant fecal occult blood test.
- Trial name
- NCT01415869
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Hepatitis C, Chronic, Hepacivirus
Adherence in Patients Receiving PegIntron Pen/Rebetol for Hepatitis C in Conjunction With a Patient Assistance Program (Study P04281)(COMPLETED)
Patients receiving a patient assistance program during therapy for Hepatitis C will be enrolled into this study. All patients will receive PegIntron pen and Rebetol according to label and the patient assistance program.
- Trial name
- NCT00704522
- Testing
- Peginterferon alfa-2b (SCH 54031), Ribavirin (SCH 18908), Patient assistance program
- Volunteers
- 601 people
- Sponsor
- Merck Sharp & Dohme LLC
Geriatrics
Efficacy of Samsung GEMS-H Device Training in Older Adults
The purpose of this study is to evaluate the feasibility of using Samsung robotic hip assist-based mobility intervention for older adults with frailty.
- Trial name
- NCT05197127
- Testing
- exoskeleton-based gait training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Khat Abuse
The Adaptation and Evaluation of the WHO's ASSIST-linked Brief Intervention to Khat-Using Ethiopian University Students
The leaves of the khat tree (catha edulis) are traditionally chewed in the countries around the Horn of Africa. They contain the amphetamine-like alkaloid cathinone and their use can produce a Substance Use Disorder.
- Trial name
- KhatAssist (NCT03730805)
- Testing
- ASSIST-linked Brief Intervention, Induction of Deliberative Mindset, Induction of Implemental Mindset
- Where
- Ethiopia
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Amyotrophic Lateral Sclerosis (ALS)
Motor-Point Stimulation for Conditioning the Diaphragm of Patients With Amyotrophic Lateral Sclerosis (ALS)
The overall goal of this research is to delay the respiratory decline of patients with Amyotrophic Lateral Sclerosis (ALS) thereby increasing their lifespan by conditioning the diaphragm with laparoscopically placed electrodes.
- Trial name
- NCT00420719
- Testing
- Intramuscular diaphragm electrodes
- Where
- 8 sites in United States, France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Synapse Biomedical
Heart Failure, Ischemic Cardiomyopathy
Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure.
The aim of the study is to investigate safety and efficacy of intramyocardial implantation of allogeneic mesenchymal stem cells in patients with end-stage ischemic cardiomyopathy undergoing left ventricular assist device…
- Trial name
- NCT01759212
- Testing
- Allogeneic stem cells implantation
- Where
- Greece
- Volunteers
- 1 people
- Sponsor
- AHEPA University Hospital
Stroke, Healthy
Gait Pattern Analysis and Feasibility of Gait Training With a Walking Assist Robot in Stroke Patients and Elderly Adults
The purpose of this study was to investigate the effects of the new wearable hip assist robot developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd., Korea) to gait rehabilitation in elderly adults…
- Trial name
- NCT02843828
- Testing
- gait rehabilitation with Samsung Hip Assist v1, gait rehabilitation without Samsung Hip Assist v1
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Coronavirus, COVID-19 Respiratory Infection
Protocol of Assistance to Patients With Covid-19 Submitted to Treatment With HD-tDCS
COVID-19 has a variety of symptoms from asymptomatic respiratory dysfunction to death. Considering the pathophysiology of SARS-CoV-2 and its relationship with the neuroimmune system, response, autonomic balance, musculoskeletal…
- Trial name
- NCT04844554
- Testing
- Active HD-tDCS 3mA
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Infertility
A Study Using Recombinant Human Chorionic Gonadotrophin (rhCG, Ovidrel®) in the Induction of Final Follicle Maturation and Early Luteinization in Chinese Women Undergoing in Vitro Fertilization and Embryo Transfer (IVF/ET)
This was an open, randomized, comparative study using rhCG (Ovidrel) in the induction of final follicle maturation and early luteinization in Chinese female subjects undergoing IVF or ET.
- Trial name
- NCT01081756
- Testing
- r-hCG, Urinary-hCG
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Heart Failure
Sacubitril/Valsartan in Left Ventricular Assist Device Recipients
The primary objective of this prospective randomised study is to assess the safety and tolerability of sacubitril/valsartan compared with standard of care used for treating BP in patients that have been implanted with the Heart…
- Trial name
- ENVAD-HF (NCT04103554)
- Testing
- Sacubitril-Valsartan, Standard of care
- Where
- 6 sites in Croatia, Czechia and 2 more
- Volunteers
- 60 people
- Sponsor
- University of Zagreb
Inflammatory Bowel Diseases
Vitamin B6 Aids in Treating Inflammatory Bowel Disease
Patients with IBD are randomized to oral administration of VitaminB6 and placebo based on the standard treatment, exploring whether VitaminB6 can increasee the clinical remission rateand improve the treatment effect of IBD…
- Trial name
- NCT06512441
- Testing
- Vitamin B6 Tablets
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Changhai Hospital
Respiratory Insufficiency, Acute Respiratory Insufficiency
NIV-NAVA vs NIV-PS/PC in Respiratory Insufficiency
This study evaluates the difference between Non Invasive Ventilation with Neurally Adjusted Ventilatory Assist (NIV-NAVA) and Conventional Non Invasive Ventilation with Pressure Support (PS) or Pressure Control (PC).
- Trial name
- NCT02592512
- Testing
- NIV-NAVA, NIV-PS/PC
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Vejle Hospital
Sleep Disorder, Circadian Dysregulation
Mini-treatment Experiments to Clarify How to Assist People to Habit Formation
Habits impact nearly every domain of one's physical and mental health. Evidence-based psychological treatments (EBPTs) are interventions targeting psychological processes that cause and/or maintain mental illness and that have…
- Conditions
- Sleep Disorder, Circadian Dysregulation, Habit, Good Sleep
- Trial name
- NCT05070143
- Testing
- RISE-UP Routine, Awareness Training, Vigilant Monitoring
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- University of California, Berkeley
Thrombosis, Bleeding
Dabigatran as an Alternative Anticoagulant in Patients With Left Ventricular Assist Device (LVAD)
Patients with severe heart failure supported by left ventricular assist device (LVAD) require adequate long-term anticoagulant therapy.
- Trial name
- NCT02872649
- Testing
- Dabigatran, Phenprocoumon
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Daniel Zimpfer, MD
Natural Pregnancy, Pregnancy, Ovarian
Genomic Imprinting and Assisted Reproductive Technologies
Genomic imprinting, referring to an epigenetic marking resulting in monoallelic gene expression, plays a critical role in development.
- Trial name
- EPIGEN (NCT00773825)
- Where
- France
- Volunteers
- 542 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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