Clinical trials: Helping Behavior
Respiratory Failure, Respiration, Artificial
Proportional Assisted Ventilation and Pressure Support Ventilation in Adult Patients With Prolonged Ventilation
A prospective randomized controlled trial was conducted to collect patients with prolonged mechanical ventilation. Patients were randomly assigned to receive PAV+ or PSV as weaning mode.
- Trial name
- NCT04140682
- Testing
- PAV+ mode, PSV mode
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Asthma in Children
Asthma Clinics Helping Expand Cost Conversations
Healthcare costs are a critical barrier to U.S. families' ability to access the preventive care needed to manage their children's asthma.
- Trial name
- Asthma CHECC (NCT04669080)
- Testing
- Health care provider cost navigation training
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tricuspid Valve Insufficiency, Right Heart Failure
Treatment of Tricuspid Valve Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation Study
The purpose of this study is to determine the utility of tricuspid valve repair at the time of LVAD implantation for patients presenting with moderate or severe tricuspid regurgitation.
- Conditions
- Tricuspid Valve Insufficiency, Right Heart Failure, Heart Failure
- Trial name
- TVVAD (NCT03775759)
- Testing
- Tricuspid valve repair or replacement, Medical management of tricuspid regurgitation
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Duke University
Dysphagia, Head and Neck Cancer
Swallowing Therapy With the Assistance of a Mobile Health Device in Head and Neck Cancer Patients: a Pan-Alberta Study
Dysphagia affects 22% of those over the age of 50, which equates to 250 million people worldwide and 360,000 in Alberta. At high risk are survivors of head and neck cancer (70%).
- Trial name
- NCT04698499
- Testing
- Swallowing exercise from home
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- University of Alberta
Respiration
Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care
The purpose of this study is to study whether neurally adjusted ventilatory assist (NAVA) provides advantages over current methods in detecting patients own breathing efforts in pediatric and neonatal ventilatory care.
- Trial name
- NCT00893087
- Testing
- Triggering mode of the ventilator, Triggering method of the ventilator
- Where
- Finland
- Volunteers
- 18 people
- Sponsor
- University of Oulu
Brachial Plexus Injury
Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries
The proposed research, the development of an innovative robotic hand orthosis with intelligent grasping control, is relevant to public health as it will restore a large measure of functionality to the paralyzed hand of a person…
- Trial name
- NCT04939233
- Testing
- Exoskeleton glove
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Carilion Clinic
Respiratory Insufficiency
Prediction of Outcome of Weaning From Mechanical Ventilation Using the Electrical Activity of the Diaphragm
Several types of spontaneous breathing trials (SBTs) have been proposed to evaluate when a patient is ready to be weaned from the ventilator based on breathing pattern measurements.
- Trial name
- OWED (NCT02539732)
- Where
- 3 sites in Canada, France and 1 more
- Volunteers
- 110 people
- Sponsor
- Unity Health Toronto
AI Assist in the Diagnosis of Pancreatic Solid Lesions
AI Assisted the Diagnosis of Pancreatic Solid Lesions
Solid lesions of the pancreas mainly include tumor and non tumor lesions. More than 90% of pancreatic tumor lesions are pancreatic cancer, which is characterized by high mortality and poor prognosis and requires surgical…
- Trial name
- NCT05706415
- Testing
- Clinicians will review the suggestions of a hypothetical AI
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Heart Failure
Comparison of Different Frailty Assessment Tools
Feasibility and Comparison of the Impact of different Frailty Assessment Tools on the Outcome of Ventricular Assist Device Implantation and Heart Transplantation in advanced heart failure patients
- Trial name
- NCT04222400
- Testing
- Frailty Assessment
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- German Heart Institute
Refractory Heart Failure
Corheart 6 LVAS Study
The primary objective of this study is to evaluate the safety and effectiveness of the Corheart 6 LVAS when used for the treatment of advanced left ventricular heart failure in a European population at 6 months post-implantation.
- Trial name
- NCT05876000
- Testing
- Corheart 6 Left Ventricular Assist System
- Where
- 11 sites in Austria, Germany and 1 more
- Volunteers
- 53 people
- Sponsor
- Shenzhen Core Medical Technology CO.,LTD.
Prematurity, Respiratory Failure
Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation
Non-invasive respiratory support has been emerging in the management of respiratory distress syndrome (RDS) in preterm infants to minimise the risk of lung injury.
- Conditions
- Prematurity, Respiratory Failure, Ventilator Lung; Newborn
- Trial name
- NCT03388437
- Testing
- NI-NAVA, NIPPV
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Fahad Armed Forces Hospital
Sleep, Cerebral Oxygenation
Respiratory Support and Brain Health in Preterm Infants
Premature babies often require breathing support during their neonatal intensive care unit stay. This is because their lungs are not fully developed to perform the work of breathing on their own.
- Trial name
- NCT05589831
- Testing
- Non-invasive Neurally Adjusted Ventilatory Assist
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Mount Sinai Hospital, Canada
Vision, Low, Child
CREATE - Children Reading With Electronic Assistance To Educate
This pilot randomized controlled trial (RCT) will test the methodology for a full RCT of assistive technologies for children/young people with low vision/blindness.
- Conditions
- Vision, Low, Child, Adolescent Development
- Trial name
- CREATE (NCT02798848)
- Testing
- Tablet computer
- Where
- 3 sites in India, United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College, London
Rectal Cancer, Surgery
Multicenter Phase II Study of Transanal TME (taTME)
Radical rectal cancer resection, namely total mesorectal excision (TME), is the cornerstone of the treatment of resectable rectal cancer.
- Trial name
- NCT03144765
- Testing
- Transanal Total Mesorectal Excision (taTME)
- Where
- 12 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acute Respiratory Failure
Non-rebreather at Flush Rate Compared to Bag Valve Mask With Assist
This crossover investigation enrolls healthy volunteers and compares the exhaled oxygen content (FeO2) between the non-rebreather mask at the flush rate and a bag-valve-mask device at the flush rate, used with active positive…
- Trial name
- NCT02841592
- Testing
- Flush rate oxygen, Flush rate oxygen with assist
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
LVAD (Left Ventricular Assist Device) Driveline Infection
Non-invasive Detection of Driveline Infections in Patients with a Left Ventricular Assist Device
The aim of this single center observational study is to determine the feasibility of using non-invasive imaging methods, including smartphone photography and infrared thermography, for detecting of DLIs in LVAD patients in terms…
- Trial name
- DRIVE-ID (NCT06867887)
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Erasmus Medical Center
Dilated Cardiomyopathy
Use of Bone Marrow Derived Stem Cell and G-CSF With Circulatory Assistance in the Treatment of DCM
DCM Support is recruiting patients with dilated cardiomyopathy and heart failure symptoms. The goal of this clinical trial is to examine whether treatment with a patient's own stem cells can improve their heart function and…
- Trial name
- DCM-Support (NCT03572660)
- Testing
- Bone marrow derived mononuclear cells and G-CSF
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Registry of Coronary Artery Ill Patients With Platelet Test Results
ONASSIST is a registry of coronary ill patients who have had a functional test measuring anti-platelet effect and/or a genetic profile of response to anti-platelet drugs.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Myocardial Infarction
- Trial name
- ONASSIST (NCT02762162)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Action, France
Early Rheumatoid Arthritis
A Randomized Clinical Trial Evaluating the Efficacy of Clinical Pharmacist Assistance Along With Pharmaceutical and Non-pharmaceutical Therapy in the Early Rheumatoid Arthritis
Background: Rheumatoid arthritis (RA) is a progressive chronic autoimmune disease with a rising global burden, in which early diagnosis and timely therapeutic intervention are critical to preventing irreversible joint damage and…
- Trial name
- NCT07726355
- Testing
- Clinical Pharmacist Led Intervention, DMARD Therapy
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Deraya University
Primary Brain Tumor, Glioma
Assistance in Neurosurgery (ExtempoRMN)
The main ambition of this project is to develop, and provide the medical community, an innovative method to analyze extemporaneously, during a neurosurgery operation, excised tissues.
- Trial name
- ExtempoRMN (NCT02272452)
- Testing
- High-Resolution Magic-Angle Spinning Nuclear Magnetic Resonance spectroscopy
- Where
- 3 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Strasbourg, France
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