Clinical trials: Helping Behavior
Respiratory Failure, Mechanical Ventilation
Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients
To evaluate the effectiveness of high assistance proportional assist ventilation (PAV+) (objective 80% gain) as main ventilatory support in early stage of critically ill patients in comparison with standard volume-assist control…
- Trial name
- NCT01204281
- Testing
- Mechanical ventilation mode (PAV+ vs. ACV)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Acute Viral Bronchiolitis
NAVA in Infants With Acute Viral Bronchiolitis: A Feasibility Study
This exploratory intervention feasibility study aims to evaluate the use of a novel mode of ventilation known as Neurally adjusted ventilatory assist (NAVA) in infants with acute viral bronchiolitis. The main aims are: 1.
- Trial name
- NCT05899894
- Testing
- Neurally Adjusted Ventilatory Assist
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Reproductive Techniques, Assisted
Use of Acetyl Salicylic Acid and Terbutalin in Assisted Reproductive Techniques (ART)
This study aims to determine the possible effects of Acetyl Salicylic Acid (ASA) and Terbutalin on ART treatment.
- Trial name
- NCT00518141
- Testing
- Acetyl Salicylic Acid and Terbutalin
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Sykehuset Telemark
Transfemoral Amputation, Artificial Limbs
Assist-Knee: Energy-Harvesting Knee Prosthesis
The purpose of this research is to validate the Assist-Knee design and function by collecting pilot data during the stand-to-sit-to-stand transition in transfemoral prosthesis users when using the Assist-Knee to harvest energy…
- Trial name
- NCT04023045
- Testing
- Assist-Knee, Habitual Prosthesis
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Orthocare Innovations, LLC
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Effects of Unilateral Robotic Assistance on Compensation Strategies and Muscular Activity During Hemiparetic Gait
Hemiparetic gait is characterized by strong asymmetries that could severely affect the quality of life of stroke survivors. This asymmetry is due to motor deficits in the paretic leg and the resulting compensations in the…
- Trial name
- NCT05138211
- Testing
- Exoskeleton assisted gait on a treadmill
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Spanish National Research Council
Instructional Virtual Realities, Weightlessness Simulation
VR-MARS Virtual Reality, Medical Assistance and Rescue for Space
VRMARS is a medical simulation study in microgravity. Healthy volunteers (n=18) test in microgravity the functionnality of an augmented reality headset in which a medical assistance is displayed.
- Conditions
- Instructional Virtual Realities, Weightlessness Simulation, Space Simulation, Patient Simulation
- Trial name
- VR-MARS (NCT06144658)
- Testing
- Augmented Reality Headset / Hololens 2 or Varjo XR3
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier de Bretagne Sud
Thromboembolism, Hemolysis
Lavare Cycle in Patients Receiving HeartWare Left Ventricular Assist Device
Left ventricular assist device (LVAD) patients remain at risk for pump thrombus and thromboembolic events through multiple mechanisms.
- Conditions
- Thromboembolism, Hemolysis, Stroke
- Trial name
- NCT04199793
- Testing
- Lavare On, Lavare Off
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- Vanderbilt University Medical Center
End-stage Heart Failure, Cardiomyopathies
VentrAssistTM LVAD for the Treatment of Advanced Heart Failure - Destination Therapy
The purpose of this study is to evaluate the safety and effectiveness of LVADs in providing long-term circulatory support for patients who have chronic stage D heart failure and are ineligible for a heart transplant.
- Trial name
- NCT00490321
- Testing
- VentrAssistTM Left Ventricular Assist Device
- Where
- 27 sites in United States
- Volunteers
- 225 people
- Sponsor
- Ventracor
Weaning Mode Comparison
PAV vs Assist Control After Failed SBT
The primary aim of this research is to determine the feasibility of conducting a randomized controlled trial comparing two ventilation modes in patients admitted to the ICU who require mechanical ventilation.
- Trial name
- NCT02773433
- Testing
- Proportional Assist Ventilation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Heart Failure
Evaluation of the Hemocompatibility of the Direct Oral Anti-Coagulant Apixaban in Left Ventricular Assist Devices
Prospective, randomized, controlled, open label, trial of LVAD patients with 1:1 randomization to either apixaban or warfarin.
- Trial name
- DOAC LVAD (NCT04865978)
- Testing
- Apixaban, Warfarin, LVAD implant
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Palak Shah
Smoking Cessation
Understanding Risk Perception, Behaviour, and Attitudes Related to Other New Tobacco Products Among Youth
To understand the risk perception, behaviour, and attitudes related to electronic cigarettes and other tobacco products among youth.
- Trial name
- NCT04416698
- Testing
- Individual qualitative interview, cross-sectional survey study
- Where
- Hong Kong
- Volunteers
- 390 people
- Sponsor
- The University of Hong Kong
Alzheimer s Disease, Vascular Dementia
Predictors of Emergency Department Use in Frail Patients
When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed.
- Conditions
- Alzheimer s Disease, Vascular Dementia, Frailty, Elderly
- Trial name
- THE-Spoke 10 (NCT07259499)
- Testing
- Plasma phosphorylated Tau 181
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Pisa
Healthy
Does Eco-driving Assistance (EDA) Have an Impact on Bus Driver's Health and Well-being?
The goal of this pragamatic trial is to assess the impact of eco-driving assistance (EDA) system on professional bus drivers' health and well-being.
- Trial name
- NCT06688721
- Testing
- Driving a bus equipped with EDA
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Pediatric Acute Respiratory Failure
Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure
It is hypothesized that the use of Neurally Adjusted Ventilatory Assist (NAVA) compared to pressure support to provide noninvasive ventilation to children will result in a decrease in the number of children with moderate to…
- Trial name
- NiNAVAped (NCT01873521)
- Testing
- Non invasive ventilation
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Hospital Universitario La Paz
Prematurity, Respiratory Failure
Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation
Non-invasive respiratory support has been emerging in the management of respiratory distress syndrome (RDS) in preterm infants to minimise the risk of lung injury.
- Conditions
- Prematurity, Respiratory Failure, Ventilator Lung; Newborn
- Trial name
- NCT03388437
- Testing
- NI-NAVA, NIPPV
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Fahad Armed Forces Hospital
Ventricular Dysfunction, Left
Characterization of the Plasma Proteome Following Left Ventricular Assist Device Implantation
The purpose of this study is to characterize changes in the plasma proteome over time following left ventricular assist device (LVAD) implantation.
- Trial name
- NCT02428894
- Testing
- LVAD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Congestive Heart Failure
The Epidemiology of Ventricular Assist Device-Related Infections
Infections often occur after ventricular assist devices (VADs) are placed. These infections can be very serious. The goal of this study is to understand why these infections occur.
- Trial name
- NCT01471795
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Obstructive Airway Disease
Clinical Study to Investigate Safety and Performance of NeuRx DPS in Patients Undergoing Bilateral Lung Transplantation
This study is a prospective, single-center feasibility study to acquire more knowledge regarding the NeuRx DPS and develop a routine in the optimal pacing of the diaphragm with this system during the weaning period from…
- Trial name
- NCT02411383
- Testing
- NeuRx Diaphragm Pacing System
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Synapse Biomedical
LVAD (Left Ventricular Assist Device) Driveline Infection
Effect of Cardiac Resynchronization Therapy (CRT) on Left Ventricular Assist Device (LVAD) Function
Certain patients with congestive heart failure are treated both by implantation of an LVAD, as well as implantation with a biventricular pacemaker.
- Trial name
- NCT04153786
- Testing
- Temporary changes in an already-implanted medical device (biventricular pacemaker)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Davis
Abdominal Laparoscopic Surgery
Application of the Maestro Surgical System for Surgical Assistance in Laparoscopic Abdominal Surgery
This study is designed to evaluate the application of the Maestro Robotic Platform for surgical assistance in laparoscopic abdominal surgery.
- Trial name
- MAESTRO (NCT07858929)
- Testing
- Any abdominal laparoscopic surgery with the usage of the Maestro Platform.
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Portsmouth Hospitals NHS Trust
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