Clinical trials: Hemifacial Spasm
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD. However, there have been no evidence of which degree of partial neuromuscular blockade should be performed during LSR…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Neuromuscular Blockade
- Trial name
- NCT01613781
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Samsung Medical Center
Hemifacial Spasm
Botulinum Toxin A in the Treatment of Hemifacial Spasm
Hemifacial spasm patients who received botulinum toxin A injection were divided into two groups. Group A received unilateral injection while group B received bilateral injection.
- Trial name
- BTATHS (NCT03306940)
- Testing
- Botulinum Toxin Type A
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji University
Blepharospasm, Hemifacial Spasm
Post Marketing Surveillance Study of Dysport
The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.
- Conditions
- Blepharospasm, Hemifacial Spasm, Cervical Dystonia, Spasmodic Torticollis
- Trial name
- NCT00210431
- Where
- 36 sites in France, Germany and 1 more
- Volunteers
- 783 people
- Sponsor
- Ipsen
Hemifacial Spasm, Intraocular Pressure
Effect of Hemifacial Spasm on Intraocular Pressure Measurement
Twenty-four consecutive patients with Hemifacial spasm and 25 age and gender-matched randomly selected eyes of healthy volunteers underwent corneal pachymetry and intraocular pressure measurements using Goldmann Applanation…
- Trial name
- NCT03390803
- Testing
- effect of hemifacial spasm on intraocular pressure
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Medipol University
Transcutaneous Electrical Acupoint Stimulation, Hemifacial Spasm
Transcutaneous Electrical Acupoint Stimulation on Postoperative Dizziness in Hemifacial Spasm Patients
To observe the prevention and treatment effect of transcutaneous electrical acupoint stimulation (TEAS) on postoperative dizziness in patients with hemifacial spasm undergoing microvascular decompression surgery, and its possible…
- Conditions
- Transcutaneous Electrical Acupoint Stimulation, Hemifacial Spasm, Dizziness
- Trial name
- NCT04621578
- Testing
- HANS 100B stimulator (4 conductors, 8 electrodes; Jisheng Co., Nanjing, China)
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Peking University People's Hospital
Hemifacial Spasm
Effect on Tear Functions of Pretarsal and Preseptal Techniques of Botulinum Toxin Type A Injection in Hemifacial Spasm
The purpose of this study is to determine whether pretarsal and preseptal techniques of Botulinum toxin type A injection have any effect on tear functions.
- Trial name
- NCT01564979
- Testing
- preseptal injection of botulinum toxin type A, pretarsal injection of Botulinum toxin type A
- Where
- Thailand
- Volunteers
- 26 people
- Sponsor
- Khon Kaen University
Hemifacial Spasm
Hemifacial Spasm and Desflurane
Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm.
- Trial name
- HFS (NCT01726725)
- Testing
- desflurane
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hemifacial Spasm
Observe Abnormal Potential From the Offending Vessel to the Facial Muscles of HFS Patients
The pathophysiologic basis of hemifacial spasm is cross-transmission between different branches of the facial nerve. The hypothesis is that the cross-transmission is mediated by the sympathetic nerve fibers on the surface of the…
- Trial name
- NCT01271634
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Neurogenic Hypertension, Hypertension
Clinical Study on the Efficacy of Microvascular Decompression in the Treatment of Neurogenic Hypertension
Hypertension has always been a threat to human health, so the prevention and treatment is of great significance. At present, the treatment of primary hypertension is mainly drug treatment, but many patients can not control their…
- Conditions
- Neurogenic Hypertension, Hypertension, Surgery
- Trial name
- NCT04791410
- Testing
- microvascular decompression
- Volunteers
- 260 people
- Sponsor
- Peking University People's Hospital
Hemifacial Spasm
Microvascular Decompressive Surgery for Hemifacial Spasm
Review the clinical outcomes of Micro vascular decompression of Hemi facial Spasm. Assess safety and efficacy of Micro vascular decompression. Improve the outcome of these patients and decease rate of recurrence and complications.
- Trial name
- NCT04474977
- Testing
- Microvascular Decompressive Surgery
- Volunteers
- 30 people
- Sponsor
- Assiut University
Benign Essential Blepharospasm, Hemifacial Spasm
Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm
The goal of this clinical trial is to test the effects of DaxibotulinumtoxinA-Lanm (Daxxify) in patients with benign essential blepharospasms (BEB) and hemifacial spasms (HFS). The main questions to answer: 1.
- Trial name
- NCT06195241
- Testing
- DaxibotulinumtoxinA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Montefiore Medical Center
Hemifacial Spasm
Study of Abobotulinum Toxin Versus Neubotulinum Toxin Injection For Hemifacial Spasm in Thai Patients
A 50-Week Prospective, Double-Blinded, Randomized, Cross-over design in Multicenter Study of 100 unit of Abobotulinum Toxin Type A (Dysport®) versus 33.33 unit of Neubotulinum Toxin Type A (Neuronox®) Injection for Hemifacial…
- Trial name
- DNHFS (NCT04589364)
- Testing
- Injection botulinum toxin A ( Dysport 100 unit or Neuronox 33.33 unit)
- Where
- 4 sites in Thailand
- Volunteers
- 107 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Blepharospasm, Hemifacial Spasm
Testing the Effect of Zinc Supplementation to Improve the Treatment Effect of Botulinum Toxin for Oculofacial Spasm
The purpose of this study is to determine whether zinc supplements are effective in enhancing the treatment of oculofacial spasm disorders with botulinum toxin.
- Trial name
- NCT01546805
- Testing
- Zinc Supplement, Sugar pill
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Hemifacial Spasm
Assessment of Effectiveness and Safety of Dysport® for the Treatment of Hemifacial Spasm
To compare the effectiveness and safety of Dysport® with the domestic Botulinum Toxin Type A (manufactured by Lanzhou Biologic Product Institute, P.R. China) for the treatment of hemifacial spasm.
- Trial name
- NCT00276315
- Testing
- Botulinum toxin type A
- Where
- 4 sites in China
- Volunteers
- 332 people
- Sponsor
- Ipsen
Hemifacial Spasm
A Multicenter, Observational Study to Evaluate Clinical Manifestation, Diagnosis and Treatment of Primary Hemifacial Spasm in Chinese Patients
To determine the clinical manifestation, diagnosis and treatment options of primary hemifacial spasm in Chinese outpatient subjects
- Trial name
- NCT01728428
- Where
- China
- Volunteers
- 1,003 people
- Sponsor
- Peking Union Medical College Hospital
Primary Dystonia, Hemifacial Spasm
Movement Disorder Survey in East China
Movement disorder involve recurring or constant muscle contractions causing squeezing or twisting movement, such as hemifacial spasm, blepharospasm, cervical dystonias etc.
- Trial name
- MDS (NCT01168388)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Sir Run Run Shaw Hospital
Hemifacial Spasm, Magnetic Resonance Imaging
Magnetic Resonance Imaging Study on Patients With Hemifacial Spasm
Up to now, multiplanar reconstruction (MPR) has been widely used to detect the neurovascular compressions (NVC) on the patients with hemifacial spasm (HFS).
- Trial name
- MRI-HFS (NCT04645277)
- Testing
- Scanning with magnetic resonance imaging
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cranial Nerve Diseases, Facial Neuralgia
CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap
Even at centers with very large experience, the risk of cerebrospinal fluid (CSF) leakage in surgery for microvascular decompression is reported up to 3%. Prevention of leakage is important since meningitis may follow.
- Conditions
- Cranial Nerve Diseases, Facial Neuralgia, Trigeminal Neuralgia, Hemifacial Spasm
- Trial name
- NCT01932255
- Testing
- prophylactic spinal tap, no prophylactic spinal tap
- Sponsor
- St. Olavs Hospital
Blepharospasm, Hemifacial Spasm
Pretarsal Versus Preseptal Botulinum Toxin for Patients With Eyelid Spasm
A triple-masked placebo-controlled trial assessing the efficacy and safety of pretarsal versus preseptal botulinum toxin for patients with eyelid spasm.
- Conditions
- Blepharospasm, Hemifacial Spasm, Botulinum Toxins, Type A
- Trial name
- NCT03508882
- Testing
- Botulinum Toxin Type A 100Unit/Vial (Product), Saline Solution for Injection
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Blepharospasm, Hemi Facial Spasm
An RCT of a Patient-initiated Treatment Service for BEB and HFS
Blepharospasm and hemifacial spasm are debilitating conditions which significantly impact on patient quality of life. Cyclical treatment with botulinum toxin injections offers temporary relief but the duration of treatment…
- Trial name
- NCT02577224
- Testing
- Patient-initiated treatment
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust