Clinical trials: Hemiparesis
Stroke, Hemiparesis
Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke
Objective: The goal of this study is to implement and test a neuro-mechanical gait assist (NMGA) device to correct walking characterized by muscle weakness, incoordination or excessive tone in Veterans with hemiparesis after…
- Trial name
- NCT04116671
- Testing
- Neuromechanical Gait Assist
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Down Syndrome, Hemiparesis
Kinematic Analysis of Manual Dexterity
The following study aims to standardize the instrumented BBT for the objective evaluation of upper limb joint kinematics using MoCap on a population of healthy subjects between 4 and 18 years of age.
- Conditions
- Down Syndrome, Hemiparesis, Healthy Subjects
- Trial name
- SUPERFUN (NCT07875127)
- Testing
- Inertial Measurement Unit and Box and Block test
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Stroke, Upper Extremity Dysfunction
Implementing Outcome Measures in Stroke Rehabilitation
The primary objective of this study is to tailor and test implementation strategies to support the adoption of two upper extremity motor outcome measures for stroke: the Fugl-Meyer Assessment and the Action Research Arm Test.
- Conditions
- Stroke, Upper Extremity Dysfunction, Hemiplegia, Hemiparesis
- Trial name
- I-STROM (NCT04888416)
- Testing
- I-STROM
- Where
- United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Hemiplegia, Hemiparesis
Evaluation of the Safety and Performance of the AWAKE Device in Patients With Hemiplegia or Hemiparesis Secondary to Stroke (ACV).
Stroke is a leading cause of disability in adults, with gait impairment being a key functional limitation. Although lower limb exoskeletons are used in rehabilitation, the available evidence focuses on bilateral devices used in…
- Trial name
- VAWAKE (NCT07867847)
- Testing
- Bionic System (AWAKE)
- Volunteers
- 20 people
- Sponsor
- Bionic Mobility Solutions, S.L.
Ischemic Stroke, Acute, Acute Hemiparesis
Effect of Exercise Gene Expression and Histone Modifications in Patients With Hemiplegia
The aim of this study is to demonstrate the effect of routine exercise program on neuroplasticity through histone acetylation and gene expression changes in acute stroke survivors from an epigenetic perspective and to investigate…
- Trial name
- NCT06726941
- Testing
- Physiotherapy and Rehabilitation Practices
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Afyonkarahisar Health Sciences University
Stroke, Hemiparesis
Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke
To determine whether treatment with transauricular vagus nerve stimulation (taVNS) during the training of an affected upper limb of a patient with chronic stroke on a robotic motor task alters the motor impairment.
- Trial name
- VaNSaRTS (NCT05339893)
- Testing
- In Motion Rehabilitation Robot
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stroke, Hemiparesis After Stroke
Optimizing Cortical Priming
Each year over 795,000 people suffer from stroke resulting in the primary cause of adult disability. Persistent upper limb dysfunction due to stroke significantly impairs performance and results in a serious decline of quality of…
- Trial name
- NCT07860073
- Testing
- 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the contralesional dorsal premotor cortex (cPMd), 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the ipsilesional primary motor cortex (iM1)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wan-Wen Liao
Stroke, Hemiparesis
Quadriceps Muscle Activity and Gait Kinematics in Patients With Post-Stroke Stiff-Knee Gait Compared With Healthy Controls
Stiff-knee gait (SKG) is a frequent gait abnormality in people with post-stroke hemiparesis and is characterized by insufficient knee flexion during the swing phase of walking.
- Trial name
- FW QUADRI (NCT07857967)
- Where
- Luxembourg
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Frédéric Chantraine
Stroke, Ischemic, Stroke Hemorrhagic
Evaluation of the Effectiveness and Safety of Keeogo™ Dermoskeleton in Subjects With Mobility Impairments Due to Stroke
A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the Keeogo™ Dermoskeleton in subjects with hemiparesis due to ischemic or hemorrhagic stroke.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Hemiparesis
- Trial name
- NCT03986320
- Testing
- Keeogo™ Dermoskeleton
- Where
- 4 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- B-Temia, Inc.
Poststroke/CVA Hemiparesis
Comparative Effects of CIMT and TOT on Hand Function Recovery in Post Stroke Patients
This controlled clinical study investigates and compares the effectiveness of CIMT and TOT in improving hand function among post-stroke patients.
- Trial name
- NCT07764939
- Testing
- Constraint-Induced Movement Therapy, Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Stroke, Post-Stroke Spasticity
ESTIM-UL: FES for Upper Limb Recovery After Stroke
Stroke is a leading cause of long-term disability, frequently resulting in impaired upper limb motor function and spasticity. Although Botulinum Toxin Type A (BoNT-A) is effective in reducing focal spasticity, functional recovery…
- Conditions
- Stroke, Post-Stroke Spasticity, Post-Stroke Hemiparesis
- Trial name
- ESTIM-UL (NCT07513714)
- Testing
- Functional Electrical Stimulation (FES), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Foggia
Stroke, Hemiparesis
Vibrotactile Feedback to Improve Walking After Stroke
Stroke survivors often walk more slowly and may have difficulty producing the movements needed to walk efficiently. This study will evaluate whether vibrotactile feedback, delivered through small wearable devices that provide…
- Trial name
- NCT07831642
- Testing
- Vibrotactile Feedback System
- Volunteers
- 32 people
- Sponsor
- Geisinger Clinic
Hemiparesis
Dance Workshop on Balance of Hemiparetic Patients
The majority of hemiparetic patients have balance disorders, which impact independence in daily living activities and walking. Conventional techniques used in rehabilitation improve balance but have shown no effects on dynamic…
- Trial name
- DanceStudio (NCT03149458)
- Testing
- dance, control
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Stroke, Hemiparesis
RGS@Home: Personalized 24/7 Home Care Post-stroke
Stroke represents one of the main causes of adult disability and will be one of the main contributors to the burden of disease in 2030.
- Conditions
- Stroke, Hemiparesis, Subacute Stroke, Chronic Stroke
- Trial name
- NCT04620707
- Testing
- RGS based training and monitoring, Therapy as usual
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Institute for Bioengineering of Catalonia
Stroke, Hemiparesis
Motor Imagery Added to Robot-Assisted Hand Rehabilitation After Stroke
Loss of upper extremity and particularly hand function after stroke reduces independence in daily activities such as eating, dressing, and personal care.
- Conditions
- Stroke, Hemiparesis, Activities of Daily Living
- Trial name
- NCT07760090
- Testing
- Robot-assisted hand rehabilitation, Motor imagery training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Stroke, Arm Weakness as a Consequence of Stroke
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
The goal of this research study is to optimize the parameter of Low-Intensity Focused Ultrasound Stimulation (LIFUS) that is most effective in changing cortical excitability and motor learning skills in patients who suffered a…
- Conditions
- Stroke, Arm Weakness as a Consequence of Stroke, Upper Extremity Hemiparesis, Upper Extremity Impairments
- Trial name
- LIFUS-OPTIMIZE (NCT07220005)
- Testing
- Low intensity focused ultrasound stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Hemiplegia and/or Hemiparesis Following Stroke
High-Intensity Laser Therapy in Hemiplegic Shoulder Pain
This randomized, sham-controlled clinical trial aims to evaluate the effectiveness of high-intensity laser therapy (HILT) combined with exercise on pain, functional status, disability, and ultrasonographic findings in patients…
- Trial name
- NCT07501416
- Testing
- High-Intensity Laser Therapy (HILT), Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kutahya Health Sciences University
Stroke, Hemiplegia
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
This study is a necessary and important step in the development of a new therapy for upper limb functional recovery in patients with severe motor impairment.
- Conditions
- Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- rTMS+CCFES (NCT03870672)
- Testing
- Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The Cleveland Clinic