Clinical trials: Hemiparesis After Stroke
Stroke, Hemiparesis
Robotic Exoskeleton Gait Training With and Without Brain-Computer Interface Control After Stroke
After a stroke, many people have trouble walking. One way to practice walking again is with a wearable robot, called an exoskeleton, that supports the legs and guides them through a walking pattern.
- Conditions
- Stroke, Hemiparesis, Gait Disorders, Neurologic
- Trial name
- NCT07760116
- Testing
- Conventional exoskeleton gait training, BCI-controlled exoskeleton gait training
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- Taichung Veterans General Hospital
Hemiparesis; Poststroke/CVA
Improving Arm Function Using Wearable Exoskeletons
The goal of this clinical trial is to compare arm and hand function with and without assistance from a wearable exoskeleton in individuals with neurological injury from a single stroke.
- Trial name
- NCT05951491
- Testing
- Wearable Shoulder Exoskeleton, Wearable Hand Exoskeleton
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Idaho
Cerebrovascular Accident, Hemiparesis
Effects of Strength Training on Upper-Limb Function in Post-Stroke Hemiparesis
Our overall goal is to develop therapeutic interventions to improve upper-limb motor function in hemiparetic persons based on an improved understanding of the mechanisms responsible for its loss and recovery.
- Trial name
- NCT00037908
- Testing
- Strength training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
Stroke, Cerebrovascular Accident (CVA)
Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- tVNS (NCT03592745)
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Stroke, Hemiparesis
Examining How Motor Rehabilitation Promotes Brain Reorganization Following Stroke, an MRI Study
Constraint-induced movement therapy (CI therapy) is a highly efficacious treatment for residual motor disability in chronic stroke.
- Trial name
- NCT01725919
- Testing
- CI therapy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Ohio State University
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Good Limb Position Management Assistive Devices on Preventing Shoulder Subluxation in Hemiplegic Patients
Stroke is a leading cause of long-term disability worldwide. During the early stage of recovery after cerebral infarction, reduced muscle tone and muscle weakness in the affected upper limb may lead to shoulder instability and…
- Trial name
- NCT07675759
- Testing
- Commercially Available Shoulder Sling, Novel Shoulder Subluxation Prevention Orthosis
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Hemiparesis After Stroke
The Impact of Neuronavigation in rTMS for Hemiplegic Stroke Patients.
This is a randomized, controlled trial investigating the efficacy and precision of neuronavigation -guided repetitive transcranial magnetic stimulation (rTMS) for motor recovery in patients with subacute stroke hemiparesis.
- Trial name
- NeurorTMS-HS (NCT07284017)
- Testing
- Neuronavigation-Assisted rTMS for Stroke Hemiparesis, Standard Localization rTMS for Stroke Hemiparesis
- Volunteers
- 30 people
- Sponsor
- Taichung Veterans General Hospital
Hemorrhagic Stroke, Hemiparesis
Dual Transcranial Direct Current Stimulation (dTDCS)-Enhanced Therapy After Hemorrhagic Strokes and VEGF
This study will evaluate the feasibility of dual tDCS to improve arm motor function in chronic stroke patients. In addition it will collect pilot data on the blood biomarkers associated with treatment effect.
- Trial name
- NCT03857243
- Testing
- dual transcranial direct current stimulation
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Stroke
Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.
The aim of the study was to explore potential pathways for recovery and adaptation of neural pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal excitability using transcranial magnetic…
- Trial name
- NCT06386627
- Testing
- Stimulus response task, Transcranial magnetic stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Hemiparesis
Blood Flow Restriction Training on Upper Limb Performance
Background; Blood flow restriction training (BFRT) is a physical intervention that promotes many beneficial muscular activities and functions when low load/intensity is used in healthy and clinical populations.
- Trial name
- NCT06859905
- Testing
- blood flow restriction training, regular exercises
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- University of Hail
Stroke, Hemiparesis of the Upper Limb Following Stroke
Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Constraint Induced Movement Therapy (mCIMT)
This clinical trial aims to evaluate the effect of different types of tDCS modulation with mCIMT in improving affected upper-limb motor function for stroke patients.
- Conditions
- Stroke, Hemiparesis of the Upper Limb Following Stroke, Stroke Rehabilitatiom
- Trial name
- tDCS and mCIMT (NCT06786000)
- Testing
- Anodal tDCS combined with mCIMT, Cathodal tDCS combined with mCIMT, Bihemispheric tDCS combined with mCIMT
- Where
- Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- King Saud University
Stroke, Hemiparesis
Proprioceptive Stimulation With Manual Bilateral Rhythmic Exercise in Post-stroke Patients
The purpose of this study is to evaluate the effect of the repetitive proprioceptive bilateral stimulation for the early recovery of the voluntary muscle contraction in stroke patients.
- Trial name
- BAT (NCT03155399)
- Testing
- Proprioceptive based training (PBT), Conventional neuromotor treatment (CNT).
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Stroke, Hemiparesis
Motor Imagery BCI Rehabilitation After Stroke
This research project will investigate motor imagery training in stroke rehabilitation during which patients receive feedback in real time from their brain activity measured with ElectroEncephaloGraphy (EEG).
- Trial name
- NCT04847089
- Testing
- Motor imagery BCI training
- Where
- 3 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Mälardalen University
Stroke, Post-Stroke Spasticity
ESTIM-UL: FES for Upper Limb Recovery After Stroke
Stroke is a leading cause of long-term disability, frequently resulting in impaired upper limb motor function and spasticity. Although Botulinum Toxin Type A (BoNT-A) is effective in reducing focal spasticity, functional recovery…
- Conditions
- Stroke, Post-Stroke Spasticity, Post-Stroke Hemiparesis
- Trial name
- ESTIM-UL (NCT07513714)
- Testing
- Functional Electrical Stimulation (FES), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Foggia
Stroke, Cerebrovascular Accident
Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Hemiparesis
This study will compare the effectiveness of different polarities of transcranial direct current stimulation paired with intensive motor training in recovery of upper extremity function in individuals with severe post-stroke…
- Trial name
- NCT03124147
- Testing
- Neuroconn Eldith stimulator by Magstim
- Volunteers
- 38 people
- Sponsor
- Lumy Sawaki
Foot Drop, Stroke
TREAT Foot Drop After Stroke With Ankle Robot
Researchers at the University of Maryland Rehabilitation and Orthopaedic Institute are looking for individuals who have suffered a stroke and have leg and ankle weakness (foot-drop), to participate in a pilot study to examine the…
- Conditions
- Foot Drop, Stroke, Hemiparesis
- Trial name
- TREAT (NCT04137809)
- Testing
- AMBLE
- Where
- United States
- Sponsor
- NextStep Robotics Inc.
Stroke With Hemiparesis
Study of Botulinum Toxin and Recovery of Hand Function After Stroke
The purpose of this study is to determine whether injections of botulinum toxin (commonly known as BOTOX®) into the affected hand of Stroke patients, while targeting the muscles controlling the hand, will lead to improved use of…
- Trial name
- NCT01422161
- Testing
- Botulinum Toxin commonly known as BOTOX®
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- NYU Langone Health
Stroke, Hemiparesis
Sideways Treadmill Training to Improve Paretic Leg Stepping in Persons Post-Stroke
People who are living in the community following a stroke fall frequently. The ability to take a step in response to a balance disturbance helps to prevent falls but stroke survivors tend not to step with their paretic leg in…
- Trial name
- NCT02516176
- Testing
- treadmill training
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University