Clinical trials: Hemiplegia and Hemiparesis
Hemiplegia, Infantile
Movement in the Non-use of the Affected Upper Extremity in Children Hemiparesis: Mirror Therapy and Action-observation
Children with cerebral palsy hemiplegia present a restriction in the daily activities due to the limitation in the active movement of the affected upper extremity.
- Trial name
- NCT04284176
- Testing
- Mirror therapy and action-observation therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Infantile Hemiplegia, Constraint Induced Movement Therapy
Intensive Therapies to Improve Manipulation in Young Children With Hemiparesis
mCIMT and BIT are therapies applied in children with hemiplegia which have a great evidence, but not in a early age. This research has the objective to know the effects of this therapies in infants diagnosed of infantile…
- Conditions
- Infantile Hemiplegia, Constraint Induced Movement Therapy, Family, Bimanual Intensive Therapy
- Trial name
- NCT06191588
- Testing
- INFANT CIMT/BIT
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- University of Seville
Cerebral Palsy (CP), Hemiplegia and Hemiparesis
Aquatic Based Exercises Versus Mirror Therapy on Hand Dexterity and Strength in Hemiplegic Child
Cerebral palsy (CP) is a neurologic disorder that affects motor function, balance, and posture, and spastic hemiplegia is found in about one-third of persons with CP and often leads to devastating upper limb disability.
- Trial name
- NCT07072416
- Testing
- Aquatic Exercise, Mirror Therapy, Designed physical therapy program.
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alaa Noureldeen Kora
Cerebral Palsy, Hemiplegia
Adaptive Arm Training for Children With Hemiplegia
The goal of this research is to provide limb training in children with hemiplegia using a bimanual-to-unimanual training approach.
- Conditions
- Cerebral Palsy, Hemiplegia, Hemiparesis, Acquired Brain Injury
- Trial name
- NCT03387449
- Testing
- Bimanual Arm Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Blythedale Children's Hospital
Cerebrovascular Accident, Hemiparesis
Optimizing Hand Rehabilitation Post-Stroke Using Interactive Virtual Environments
The complexity of sensorimotor control required for hand function as well as the wide range of recovery of manipulative abilities makes rehabilitation of the hand most challenging.
- Conditions
- Cerebrovascular Accident, Hemiparesis, Hemiplegia
- Trial name
- NCT01072461
- Testing
- HAS Training, HAT training, Bimanual Training
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- New Jersey Institute of Technology
Spasticity as Sequela of Stroke, Stroke
Transcutaneous Spinal and Peripheral Stimulation and Wrist Robotic Therapy for Patients With Spastic Stroke
The purpose of this study is to investigate if two courses of five consecutive sessions of noninvasive spinal stimulation paired with peripheral nerve stimulation at the forearm provided by an investigational device (Doublestim™/…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Stroke Sequelae, Hemiplegia, Spastic
- Trial name
- NCT04113525
- Testing
- MyoRegulator™ System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Northwell Health
Spastic Hemiparesis, Muscle Spasticity
A Study to Collect Participants Experience of Living With Adult Upper Limb (AUL) Spasticity and to Assess the Arm Activity Measure (ArmA)
The participants of this study will have AUL spasticity and have a need for botulinum toxin type A injections. AUL spasticity is where people develop tightening or stiffness of the muscles in the arms.
- Trial name
- NCT05546190
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Ipsen
Hemiplegia and Hemiparesis
Mirror Therapy vs Cross Education Non Paretic Limb Training on Strength and Hand Dexterity in Stroke Survivors.
A stroke is a significant contributor to functional decline and long-term disability. The reduction of obesity and improvement in quality of life are directly correlated.
- Trial name
- NCT06059755
- Testing
- Cross education, Mirror Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Stroke, Hemiparesis After Stroke
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower…
- Conditions
- Stroke, Hemiparesis After Stroke, Chronic Stroke Patients, Hemiplegia
- Trial name
- NIMBLE (NCT07073235)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- Danderyd Hospital
Stroke, Stroke, Acute
Safety Evaluation of the ReWalk ReStore Device in Subjects With Mobility Impairments Due to Stroke
A multi-site, interventional, non-comparative, single-arm trial to evaluate the safety of the ReWalk ReStore device in subjects with hemiplegia/hemiparesis due to ischemic or hemorrhagic stroke.
- Conditions
- Stroke, Stroke, Acute, Stroke Hemorrhagic, Hemiparesis
- Trial name
- NCT03499210
- Testing
- ReWalk ReStore device
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- ReWalk Robotics, Inc.
Cerebral Palsy (CP), Spastic Hemiparesis
Cross-Training and Locomotor Abilities in Cerebral Palsy
The purpose was to investigate the effect of cross-training as a method of unilateral motor priming on locomotor abilities in children with spastic unilateral cerebral palsy.
- Trial name
- NCT06750081
- Testing
- Physical Therapy, Designed rehabilitation program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hemiparesis, Balance
Effect of Incorporating Perceptual Learning Into Plantar Hardness Discrimination on the Risk of Falling and Muscle Torque in Patients With Hemiplegia
Hemiplegia, a common stroke sequela, significantly impairs motor function, leading to balance issues and increased fall risk. Traditional rehabilitation methods often fall short in fully restoring function.
- Trial name
- NCT07077837
- Testing
- Study Group, Control
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
Speech and Language Disorder, Cerebral Palsy
Effect of mCIMT Casting on Speech-language Outcomes in Children With Hemiparesis
Modified constraint-induced movement therapy (mCIMT) has been successfully used with children who have hemiplegia (weakness or paralysis on one side of the body.) mCIMT uses a removable cast during treatment and home exercise…
- Conditions
- Speech and Language Disorder, Cerebral Palsy, Hemiplegia, Hemiparesis
- Trial name
- NCT04259814
- Testing
- Speech-language therapy (SLT), Modified constraint-induced movement therapy (mCIMT)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Shirley Ryan AbilityLab
Spastic Cerebral Palsy
Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy
The investigators hypothesize that children with spastic cerebral palsy will show greater improvements in gross motor function, associated developmental skills and growth after the 3 months of myofascial structural integration…
- Trial name
- NCT01815814
- Testing
- Rolfing / Myofascial Structural Integration
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Hemiplegia and/or Hemiparesis Following Stroke
The Effect of Good Limb Position Management Assistive Devices on Preventing Shoulder Subluxation in Hemiplegic Patients
Stroke is a leading cause of long-term disability worldwide. During the early stage of recovery after cerebral infarction, reduced muscle tone and muscle weakness in the affected upper limb may lead to shoulder instability and…
- Trial name
- NCT07675759
- Testing
- Commercially Available Shoulder Sling, Novel Shoulder Subluxation Prevention Orthosis
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Unilateral Cerebral Palsy
Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
In France, Cerebral Palsy (CP) affects 1 in 450 births. It results from lesions of the brain, before, during, or shortly after birth. These non-progressive lesions cause muscle impairments, responsible for activity limitations.
- Trial name
- MouvsupTCIHemi (NCT03099993)
- Testing
- Measurement of maximal forces of elbow pronosupination and flexion-extension
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Cerebral Palsy (CP), Hemiparetic Cerebral Palsy
Robot-Assisted Mirror Therapy in the Rehabilitation of Hemiparetic Cerebral Palsy
The goal of this clinical trial is to learn whether robot-assisted mirror therapy improves upper extremity function in children with spastic hemiparetic cerebral palsy.
- Trial name
- NCT07763691
- Testing
- Robot-Assisted Mirror Therapy, Mirror Therapy, Neurodevelopmental Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Cerebral Palsy, Hemiplegic Cerebral Palsy
tDCS and Bimanual Therapy for Children With Hemiplegic Cerebral Palsy
The goal of this study is to test the efficacy of transcranial direct current stimulation combined with bimanual training on hand function in children with unilateral spastic cerebral palsy (USCP).
- Conditions
- Cerebral Palsy, Hemiplegic Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Spastic Hemiparesis
- Trial name
- NCT03402854
- Testing
- active transcranial direct current stimulation, bimanual training
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Burke Medical Research Institute
Spastic Hemiparesis
Study to Evaluate Effects of DYSPORT® Injected in Lower and Upper Limb Combined With Guided Self-Rehabilitation Contract (GSC)
The purpose of this clinical study is to assess whether AbobotulinumtoxinA (Dysport®) injections in upper and lower limbs accompanied with a personal exercise plan called "Guided Self-rehabilitation Contract" (GSC) can improve…
- Trial name
- ENGAGE (NCT02969356)
- Testing
- Botulinum toxin type A, GSC
- Where
- 19 sites in United States, Czechia and 2 more
- Volunteers
- 157 people
- Sponsor
- Ipsen
Stroke, Hemiplegia
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
This study is a necessary and important step in the development of a new therapy for upper limb functional recovery in patients with severe motor impairment.
- Conditions
- Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- rTMS+CCFES (NCT03870672)
- Testing
- Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The Cleveland Clinic