Clinical trials: Hemodialysis Complication
Hemodialysis Complication
Auricular Acupressure and Fluid Restriction Program on Salivary Flow and Fluid Adherence in Children on Hemodialysis
This study aims to evaluate the effects of auricular acupressure on salivary flow rate and fluid restriction adherence among children undergoing Hemodialysis .
- Trial name
- NCT06562959
- Testing
- Fluid Restriction Program, Intervention Bundle (Fluid Restriction Program and Auricular Acupressure
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Diabetes Mellitus, Renal Failure
The Effects of Hemodialysis on Serum Sclerostin Levels
Background: Parathyroid hormone (PTH) and 1,25-dihydroxy vitamin D (1,25-OHD) as well as mineral bone metabolism modulators like sclerostin are thought to play an important role in in diabetic patients with chronic renal failure.
- Conditions
- Diabetes Mellitus, Renal Failure, Hemodialysis Access Failure
- Trial name
- sclerostin (NCT03952819)
- Testing
- serum sclerostin
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
End Stage Renal Disease
Impact of Hemodialysis on Exhaled Volatile Organic Compounds in End Stage Renal Disease
End stage renal disease (ESRD) is a severe clinical state of irreversible loss of endogenous kidney function, shortening life expectancy, if left untreated.
- Trial name
- NCT01684228
- Where
- Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Renal Impairment
Pharmacokinetics of Yimitasvir Phosphate Capsule in Subjects With Normal Renal Function and ESRD
This study is to evaluate the single-dose pharmacokinetics (PK) and safety of Yimitasvir phosphate capsule in participants with End-stage renal disease without hemodialysis using matched healthy participants as a control group.
- Trial name
- NCT04565171
- Testing
- Yimitasvir Phosphate Capsule
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Focal Segmental Glomerulosclerosis
Permeability Factor in Focal Segmental Glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) is a renal syndrome characterized by proteinuria (usually nephrotic range), limited response to conventional therapy, and a poor renal prognosis, with progression to end stage renal…
- Trial name
- NCT00007475
- Testing
- Plasma exchange, Cyclophosphamide
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Renal Insufficiency, Hemodialysis
Effect of a Concurrent Physical Exercise Program in Hemodialysis Patients
Concurrent physical exercise is the method of combining strength and endurance that can be worked with in one session or in an exercise program.
- Trial name
- NCT06664385
- Testing
- concurrent physical exercise
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pedro Julian Flores Moreno
Renal Impairment
A Study to Evaluate the Drug Levels of Mezigdomide in Adult Participants With Renal Impairment
The purpose of this study is to evaluate the drug levels of mezigdomide in participants with renal impairment.
- Trial name
- NCT06318676
- Testing
- Mezigdomide
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Celgene
Hemodialysis Complication
REIKI APPLICATION PAIN, FATIGUE AND ITCHING IN HEMODIALYSIS PATIENTS
The research sample consisted of 74 individuals, including the intervention group (n=37) and the control group (n=37), who received hemodialysis treatment at Sivas Cumhuriyet University Application and Research Hospital…
- Trial name
- NCT05531175
- Testing
- Reiki apply
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
ESRD, Influenza Vaccine
Efficacy of Different Doses of Influenza Vaccine in Chronic Hemodialysis Patients
This study was a randomized controlled trial to investigate the immune response of influenza vaccines when doses were increased.
- Conditions
- ESRD, Influenza Vaccine, Seroprotection
- Trial name
- Enhance (NCT05070494)
- Testing
- Egg-derived standard dose trivalent influenza vaccine (surface antigen, inactivated)
- Where
- Thailand
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Mahidol University
End Stage Renal Disease
Effect of Behavioral Intervention on Interdialytic Weight Gain in Patients Undergoing Hemodialysis
A randomized clinical trial will be conducted in which effect of behavioral intervention (Text message of dietary salt and fluid restriction) on inter-dialytic weight gain in hemodialysis patients.
- Trial name
- NCT04892225
- Testing
- Technology-supported behavioral intervention (text message)
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Farooq Hospital - West Wood Branch
Chronic Kidney Disease Requiring Chronic Dialysis, Vaccine Response
Impact Of Kidney Failure On The Regulation Of Humoral Response To Vaccination
The aim of this observational study is to determine if and how kidney failure affects the development of protective immune responses following vaccination in patients on chronic dialysis.
- Trial name
- Tfh-CKD (NCT06635525)
- Testing
- Influenza vaccination, SARS-CoV-2 vaccine
- Where
- 3 sites in Italy
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Hemodialysis Complication
Difference Between Interval and Continous Intradialytic Exercise on Functional Capacity in Hemodialysis Patient
The goal of this study is to find out the effect of interval versus continous intradialytic training on muscle quality index and functional capacity in Hemodialysis patients.
- Trial name
- NCT05722496
- Testing
- Aerobic pedaling exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Renal Impairment
Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function
Evaluation of the pharmacokinetics (PK) of SPR206 in subjects with normal renal function, subjects with various degrees of renal insufficiency, and subjects with end-stage renal disease (ESRD) receiving hemodialysis (HD) therapy.
- Trial name
- NCT04865393
- Testing
- SPR206
- Where
- 2 sites in New Zealand
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Spero Therapeutics
Chronic Kidney Disease
Opioids in Chronic Kidney Disease Patients Undergoing Hemodialysis
To measure oxycodone's intradialytic mass transfer rate coefficient and oxycodone's removal rate using an ODE/PDE hemodialysis model.
- Trial name
- OCKD (NCT02452437)
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emerio & Lourdes Linares Research and Education Center
Renal Impairment
A Study to Investigate the Effect of Renal Function and Hemodialysis on the Pharmacokinetics (PK) of RO7079901
This is a multi-center, non-randomized, open-label, two-part study to investigate the effect of renal function and hemodialysis on PK of RO7079901.
- Trial name
- NCT02975388
- Testing
- RO7079901
- Where
- 5 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Chronic Kidney Disease Requiring Chronic Dialysis
Activation of the Contact System and the Immune System in Patients With Chronic Kidney Disease.
Patients with end-stage renal disease undergoing hemodialysis (HD) are burdened with extremely high mortality rates (15% per year) and during the early stage (≤120days) the mortality rate is even higher (27% per year).
- Trial name
- AKIM-CKD (NCT05266092)
- Testing
- Observational study
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Complication of Hemodialysis
The Efficacy of Alcohol After Betadine and Combination of Alcohol and Betadine on Inflammation Vascular Access
The purpose of this study was to compare the efficacy of combination of alcohol and povidone iodine 10% and Alcohol 70% after povidone iodine 10% on inflammation and infection related to vascular access area in hemodialysis…
- Trial name
- NCT02263196
- Testing
- Alcohol and povidone iodine, combination of alcohol and betadin
- Where
- Iran
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Chronic Kidney Diseases, Hemodialysis Complication
Exposure Of Bisphenol Analogues In Chronic Kidney Disease and Dialysis Patients
In this retrospective study, the serum levels of Bisphenol A (BPA) and three BPA analogs, namely, bisphenol B (BPB), bisphenol S (BPS), and bisphenol F (BPF), in patients with CKD, patients on dialysis therapy and healthy control…
- Trial name
- NCT04100421
- Where
- China
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Chronic Renal Insufficiency, Pruritus
The Efficacy of VR and AR on Pruritus
The research will be conducted randomly in order to determine the effect of VR and AR on pruritus symptom.
- Conditions
- Chronic Renal Insufficiency, Pruritus, Itch
- Trial name
- NCT04289038
- Testing
- Autogenic Relaxation, virtual reality game application, kidney function narration
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hemodialysis Access Failure
Balloon-Assisted Maturation of Autogenous Arteriovenous Fistulae
Background: There are several studies that document the safety and efficacy of the balloon-assisted maturation (BAM) technique. Ultimately, there are also studies that report its possible negative consequences such as fibrosis…
- Trial name
- NCT04263116
- Testing
- Balloon Assisted Maturation
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mansoura University