Clinical trials: Hemodialysis Patients
Chronic Renal Failure
A Trial to Investigate the Efficacy and Safety of Orally Administered Tolvaptan (OPC-41061) in Patients With Chronic Renal Failure Undergoing Hemodialysis or Hemodiafiltration
This is a study to investigate the efficacy and safety of OPC-41061 by 24-week oral administration of OPC-41061 at 15-mg or 30-mg or placebo in patients with chronic renal failure who are undergoing hemodialysis or…
- Trial name
- NCT02331680
- Testing
- OPC-41061
- Where
- 4 sites in Japan
- Volunteers
- 124 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Bacteremia
Prophylactic Antimicrobial Catheter Lock
This is a randomized, double blinded, prospective, multicenter, clinical trial of the use of Heparin versus Gentamicin as a pos-dialysis catheter lock solution.
- Trial name
- ALLOCK (NCT00571259)
- Testing
- Heparin 1000U/mL, 4% Sodium Citrate with Gentamicin 320 mcg/mL
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Satellite Healthcare
Hypotension
HFR A-equilibrium on Cardiovascular Stability
Aim of the present randomized controlled multinational trial is the comparison of a novel biofeedback system on sodium profiling applied to a endogenous hemodiafiltration therapy, with the standard (no sodium profiling)…
- Trial name
- AIMS (NCT01414842)
- Testing
- Automated sodium profiling in endogenous hemodiafiltration, Standard sodium dialysate
- Where
- 12 sites in Belgium, France and 3 more
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera di Lecco
Hyperparathyroidism; Secondary, Renal
Bone Markers and Bone Density Changes in Hyperperparathyroid Dialysis Patients Under Cinacalcet Treatment
Chronic kidney disease related mineral and bone disorders (CKD-MBDs) and secondary hyperparathyroidism (SHPT) are observed in most patients with chronic kidney disease on dialysis (CKD-5D).
- Trial name
- NCT04637360
- Testing
- Cinacalcet Tablets, calcitriol
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Min-Sheng General Hospital
All Cause Mortality
Heat Disinfection of HD Water Treatment System in Hemodialysis Patients
Hemodialysis (HD) may lead to increase inflammatory response through a number of mechanisms. HD-related inflammation is mainly due to underlying kidney disease, coexisting comorbidities, uremia per se, dialyzer membrane…
- Trial name
- NCT01138280
- Testing
- CWP 103H (Gambro, Sweden): a heat disinfection device
- Where
- Taiwan
- Volunteers
- 540 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Kidney Disease, Coronary Artery Disease
Involvement of FFA Metabolism and Insulin Resistance in Cardiac Death
The investigators evaluated predictive values of myocardial fatty acid metabolism and insulin resistance for cardiac death of hemodialysis patients with normal coronary arteries.
- Conditions
- Kidney Disease, Coronary Artery Disease, Hemodialysis
- Trial name
- CD_HD_FAIR (NCT01068080)
- Where
- Japan
- Volunteers
- 155 people
- Sponsor
- Toujinkai Hospital
Hemodialysis
Aerobic Exercises and Hemodialysis Patients
Patients undergoing hemodialysis (HD) frequently exhibit elevated serum uric acid (SUA) levels, which are associated with cardiovascular risks, joint issues, and diminished quality of life (QoL).
- Trial name
- NCT07076888
- Testing
- Aerobic Exercises, Conventional Program
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
End Stage Renal Disease
Safety and Effects of Supplementation With Ergocalciferol on Erythropoietin Dosing in Hemodialysis Patients
A few studies have reported erythropoiesis-stimulating agent (ESA) doses before and after 25D supplementation, but only one of these is a prospective clinical trial, and it is a small, single center study lacking a control arm.
- Trial name
- NCT01395823
- Testing
- ergocalciferol supplementation
- Where
- 12 sites in United States
- Volunteers
- 470 people
- Sponsor
- Dialysis Clinic, Inc.
Kidney Diseases, Renal Insufficiency
Efficacy and Tolerability of ILY101 in Dialysis Patients With Hyperphosphatemia
This is a randomized, dose-ranging, efficacy and tolerability study in chronic kidney disease patients with hyperphosphatemia on hemodialysis. Patient participation in the study is approximately 10 weeks in duration.
- Trial name
- NCT00358046
- Testing
- ILY101
- Where
- 18 sites in United States
- Volunteers
- 120 people
- Sponsor
- Ilypsa
Nurse's Role
Effectiveness of Massage Applied to Hemodialysis Patients
This study was conducted to determine the effect of massage on comfort and fatigue levels of hemodialysis patients.
- Trial name
- NCT06604403
- Testing
- Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Zeynep Yildirim
Hemodialysis, Citrate
The Effect of Citrate Dialysate on Clot Formation and Anemia in Hemodialysis Patients
Acetate-free citrate containing dialysate is expected to be clinically effective in maintaining hemodynamic stability during hemodialysis (HD).
- Conditions
- Hemodialysis, Citrate, Heparin
- Trial name
- NCT03470727
- Testing
- Citrate dialysate
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Pruritus Chronic, Kidney Diseases, Chronic
Anrikefon vs Nalfurafine for Sleep Quality in Hemodialysis Patients With CKD-aP
The goal of this clinical trial is to compare a new intravenous drug, Anruikefen, with a traditional oral medication, nalfurafine orally disintegrating tablets, in improving sleep quality in patients with chronic kidney…
- Conditions
- Pruritus Chronic, Kidney Diseases, Chronic, Renal Insufficiency, Chronic, Uremia; Chronic
- Trial name
- Anrikefon (NCT07380113)
- Testing
- Anrikefon, Nalfurafine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhujiang Hospital
Hemodialysis, Hypercholesterolemia
Malnutrition and Inflammation in Dialysis Patients in Taiwan
According to the reports of the United States Renal Data System (USRDS), there is a 25% annual mortality rate with nearly 50% of all reported maintenance hemodialysis (HD) patient deaths attributed to atherosclerosis-related…
- Conditions
- Hemodialysis, Hypercholesterolemia, Malnutrition, Inflammation
- Trial name
- NCT00173823
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- National Taiwan University Hospital
Acute Myocardial Infarction, Congestive Heart Failure
Nicorandil Study to Reduce Cardiac Death After Percutaneous Coronary Intervention (PCI) in Hemodialysis Patients
Survival after invasive coronary revascularization is worse in patients with chronic kidney disease than in those without it. The investigators aimed to examine whether oral administration of nicorandil, a hybrid of nitrate and…
- Trial name
- NCT00848562
- Testing
- Nicorandil
- Where
- Japan
- Volunteers
- 129 people
- Sponsor
- Toujinkai Hospital
Intradialytic Hypotension, Cardiac Event
BIA Versus Physician Adjustment in Acute Kidney Injury Patients Requiring Renal Replacement Therapy
This study was designed to compare the efficacy of BIA and physician adjustment to prevent intradialytic hypotension in patients with acute kidney injury who received renal replacement therapy.
- Conditions
- Intradialytic Hypotension, Cardiac Event, Renal Insufficiency, Hospital Length of Stay
- Trial name
- NCT03916861
- Testing
- Bioelectrical Impedance Analysis, Physician-guided
- Where
- Thailand
- Volunteers
- 9 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Chronic Kidney Disease Stage 5
Study to Assess Pegloticase (KRYSTEXXA®) in Patients on Hemodialysis
This is a Phase 1 single dose study conducted to evaluate the PK and PD of pegloticase administered to hemodialysis patients. A single dose of pegloticase will be administered intravenously to male or female hemodialysis patients…
- Trial name
- NCT01739660
- Testing
- Pegloticase
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Savient Pharmaceuticals
Chronic Renal Failure Requiring Hemodialysis
Oxidative Stress on Muscle Dysfunction in Hemodialysis Patient
In hemodialysis patient (HD) a reduction of the skeletal muscle mass and strength has previously been reported. This muscle impairment constitutes an independent prognosis factor in HD patients.
- Trial name
- POPEYE (NCT02794142)
- Testing
- renal transplantation, No intervention
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Disease 5D, Hyperkalemia
Nurse-Led Nutritional Education for Moroccan Dialysis Patients
Why was this study done? Many dialysis centers in Morocco lack dietitians to provide proper, individualized dietary support to patients.
- Conditions
- Chronic Kidney Disease 5D, Hyperkalemia, Hemodialysis
- Trial name
- NCT07277530
- Testing
- Nutritional Education Intervention
- Where
- Morocco
- Volunteers
- 30 people
- Sponsor
- HASSAN 1st university
Uremic Pruritis
Sertraline Effect in Uremic Pruritis
This study aims to assess the effect of sertraline on uremic pruritis in patients undergoing regular haemodialysis.
- Trial name
- NCT05341843
- Testing
- sertraline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Chronic Kidney Disease Requiring Chronic Dialysis
Intradialytic Resistance Training in Haemodialysis Patients
The study will investigate the effects of an intradialytic resistance training on miRNA´s expression and muscle strength in haemodialysis patients.
- Trial name
- IRTHEP (NCT03511924)
- Testing
- Intradialytic resistance training
- Where
- Slovakia
- Volunteers
- 90 people
- Sponsor
- Pavol Jozef Safarik University
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