Clinical trials: Hemodilution
Healthy
Comparison of Rainbow INVSENSOR00001 and Control SpHb Disposable Sensor Performance During Hemodilution
This study involves comparison of the performance of two SpHb sensors in subjects that undergo a hemodilution procedure. The sensors' performance will be assessed by comparison of the measured hemoglobin values against reference…
- Trial name
- NCT03273166
- Testing
- INVSENSOR00001, Control SpHb sensor, Hemodilution
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Pulmonary Edema
Thoracic Fluid Content During Hypervolemic Hemodilution
Thoracic fluid content (TFC) is one of the many variables measured by the ICON electrical cardiometry (EC) device (Osypka Medical).
- Trial name
- NCT04689516
- Testing
- Thoracic fluid content estimation
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypoxia, Hemodilution
Hypoxia and Hemodilution Testing in Healthy Adult Volunteers
This study will collect physiological measurements in healthy adult volunteers under controlled hypoxia and hemodilution conditions.
- Trial name
- NCT07503171
- Testing
- Noninvasive Physiological Monitoring Device
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Nihon Kohden
Healthy
Hemodilution Validation of INVSENSOR00026
In this study, the concentration of hemoglobin within the subject's blood will be reduced in a controlled manner by administering fluids intravenously.
- Trial name
- NCT03677375
- Testing
- INVSENSOR00026
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Postoperative Hemorrhage, Postoperative Anemia
Autologous Whole Blood Management for Transfusion Reduction in Adult Cardiac Surgery Patients
The goal of this pilot trial is to test a protocol for a planned Canada-wide clinical trial looking at whether or not the use of a patients own blood works as good as the current standard of care using donated blood products to…
- Conditions
- Postoperative Hemorrhage, Postoperative Anemia, Postoperative Blood Loss
- Trial name
- NCT05889494
- Testing
- Autologous Whole Blood Management, Standard Care involving allogenic and/or derivative transfusion.
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Surgical Blood Loss, Burns
Measurement of Blood Volume Loss During Burn Surgery
Burn surgery is associated with significant reductions in hematocrit. However, it is unclear whether these reductions are the result of hemodilution from non-red cell containing intraoperative transfusions or from loss of red…
- Trial name
- NCT03340116
- Testing
- Burn surgery, Measurement of RBC volume, plasma volume, and total blood volume using Daxor BVA-100
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Hemodilution, Hemorrhage
Proving Hemodilution in a Human Model for Class I Hemorrhage
This study is a randomized control trial in volunteer blood donors to quantify the effect of blood loss and subsequent crystalloid infusion on hemoglobin and markers of resuscitation such as base deficit and lactate.
- Conditions
- Hemodilution, Hemorrhage, Shock, Wounds and Injuries
- Trial name
- NCT02318355
- Testing
- normal saline, lactated ringers
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hypovolemia, Hypervolemia
Pilot Validation of a Hemodilution Technique to Estimate Blood Volume in Vivo
The objective of this study is to determine the accuracy of estimating patient blood volume using field-expedient point-of-care measurement of hematocrit before and after hemodilution with a standardized volume of intravenous…
- Trial name
- NCT03031600
- Testing
- Radiodilution via Daxor BVA-100, Hemodilution via hematocrit measurement
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Hip Replacement Arthroplasty
Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate.
- Trial name
- NCT00542516
- Testing
- Hydroxyethyl Starch, Ringer's lactate
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Platelet Dysfunction, Hemodilution
Effect of Aspirin, Hemodilution and Desmopressin on Platelet Dysfunction
Study hypothesis: Desmopressin (DDAVP) can improve platelet function under influence of aspirin, hemodilution and mild hypothermia Mild hypothermia (34-35oC) is known to cause platelet dysfunction.
- Conditions
- Platelet Dysfunction, Hemodilution, Mild Hypothermia, NSAID
- Trial name
- NCT01382134
- Testing
- Aspirin, desmopressin
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dilutional Coagulopathy
Hemodilution and Coagulopathy With 3 Colloids
Aim of this in vitro trial is to assess the effect on blood coagulation after 60 % dilution with different colloids (HES 130/0.42, Gelatin and Gelatin balanced) and investigate reversibility by replacement of fibrinogen (FBG)…
- Trial name
- NCT01727830
- Testing
- Induced Coagulopathy by HES (Tetraspan), Gelatin (Physiogel), Gelatin balanced (Physiogel balanced)
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Acute Kidney Injury
Acute Normovolemic Hemodilution on Urine Neutrophil Gelatinase-associated Lipocalin Levels
Acute normovolemic hemodilution (ANH) is performed as a blood conservation technique during surgical procedures with high risk for significant blood loss.
- Trial name
- NCT05349292
- Testing
- ANH
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore