Clinical trials: Hemodynamic
Coronavirus, SARS-CoV-2
Hemodynamic Characteristics of Patients With SARS-CoV-2
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a public health emergency of international concern.
- Conditions
- Coronavirus, SARS-CoV-2, COVID-19, Acute Respiratory Distress Syndrome
- Trial name
- PiCCOVID (NCT04337983)
- Testing
- Transpulmonary thermodilution, Echocardiography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Bicetre Hospital
Heart Failure
Hemodynamic Testing Strategies to Assess Pulmonary Hypertension in Heart Failure
The goal of this observational study is to learn about heart function and high lung blood pressure in patients with heart failure.
- Trial name
- NCT05672719
- Testing
- Right Heart Catheterization
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- Mount Sinai Hospital, Canada
Respiratory Abnormality, Pulmonary
The Study Examined the Acute Effects of Wim Hof on Aerobic Training and Cardiodynamics.
Researchers will split the sixty healthy smokers in half. Thirty people will serve as a control group and will be asked to walk or jog at a controlled pace for twelve minutes as part of an aerobic exercise program.
- Conditions
- Respiratory Abnormality, Pulmonary, Exercise Training
- Trial name
- NCT07399119
- Testing
- aerobic exercise where it included walking/ jogging with a controlled speed by the participant, Wim Hof Breathing Method
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Cairo University
Video-Assisted Thoracic Surgery
Hemodynamic and Inflammatory Responses in Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) for thoracic surgery is practical, has been shown to reduce postoperative discomfort, and has improved cosmetic results when compare to open thoracotomy.
- Trial name
- NCT02647775
- Testing
- multi-port VATS, single-port VATS
- Where
- Taiwan
- Volunteers
- 63 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Tumors, Hypotension
Levobupivacaine and Lidocaine for Paravertebral Block Causes Greater Hemodynamic Oscillations Than Levobupivacaine
The purpose and the goal of this paper is to show whether the application of a combination of two local anesthetics, as opposed to the application of one local anesthetic at paravertebral block changes the hemodynamic variable.
- Conditions
- Breast Tumors, Hypotension, Bradycardia
- Trial name
- NCT02004834
- Testing
- levobupivacaine
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Scalp Block
Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients"
The goal of this clinical trial is to learn if an ultrasound-guided scalp block can improve intraoperative hemodynamic stability and provide better postoperative pain relief in adult patients undergoing elective supratentorial…
- Trial name
- NCT07496632
- Testing
- Surgical site infiltration with plain bupivacaine, Scalp block with plain bupivacaine
- Where
- Bangladesh
- Volunteers
- 72 people
- Sponsor
- Bangladesh Medical University
Monitoring
Comparison of Hemodynamic Variables Between Using Conventional Invasive Catheter Monitoring and Non-invasive Piezoelectric Sensor
Arterial pressure is obtained from invasive arterial monitoring and noninvasive arterial monitoring using piezoelectric sensor and compared.
- Trial name
- NCT07110506
- Testing
- Arterial pressure monitoring
- Volunteers
- 30 people
- Sponsor
- SMG-SNU Boramae Medical Center
Heart Failure
Myocardial Hemodynamic Effects of Levosimendan
This study will test the hypothesis that mechanical efficiency as measured by pressure-volume loop assessment should improve during short-term treatment with intravenous levosimendan.
- Trial name
- NCT00585104
- Testing
- levosimendan
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Healthy
Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia
The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.
- Trial name
- NCT00199784
- Testing
- Phenylephrine
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Type 2 Diabetes Mellitus
TRENDY Follow-up: Study on Endothelial Function in Subjects With Type 2 Diabetes Mellitus
Basal nitric oxide (NO) activity plays a pivotal role in the regulation of glomerular hemodynamics, and in animal experiments its alteration has been associated with morphological changes characteristic of diabetic nephropathy.
- Trial name
- NCT00905528
- Testing
- Telmisartan 80 mg/d, Ramipril 10 mg/d
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability
The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability During Anesthesia Induction in Adults.
The aim of our study to compare two different doses of Dexmedetomidine added to anesthetic dose of ketamine in the induction of general anesthesia in adult patients regarding the hemodynamic profile, adequacy of hypnosis…
- Trial name
- NCT05948267
- Testing
- ketamine- dexmeditomidine admixure, Propofol, Lidocaine and fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Kasr El Aini Hospital
Septic Shock, Cerebral Autoregulation
Effects of Targets of Blood Pressure on Cerebral Hemodynamics in Septic Shock
The sudy objective is to evaluate the cerebral haemodynamic status in different ranges of systemic arterial pressure in patients with septic shock by noninvasive tools, transcranial doppler and intracranial compliance by…
- Trial name
- NCT05833607
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- D'Or Institute for Research and Education
Growth and Development
fMRI Study to Investigate Hemodynamic Changes in Brain Resulting From Supplementation of Bacopa Monnieri Extract and Multiple Micronutrient Supplementation.
The study will aim to compare the effects of a beverage powder fortified with multiple micronutrients and Bacopa monnieri extract (test product) to a non-fortified isocaloric beverage powder (control product) on cognitive…
- Trial name
- NCT02345187
- Testing
- Beverage powder fortified with Bacopa Monnieri Extract and Multiple Micronutrient supplementation, Non-fortified isocaloric beverage powder
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Trauma, Pelvic Fracture
Pelvic Fractures in Polytraumatized Patients With Hemodynamic Instability: Angioembolization vs Preperitoneal Packing
Pelvic fracture is a usual injury in trauma patients. An unstable trauma patient with a pelvic fracture has an elevated risk of death due to pelvic bleeding and the associated injuries.
- Conditions
- Trauma, Pelvic Fracture, Hemodynamic Instability
- Trial name
- NCT04764864
- Testing
- Angioembolization, Preperitoneal Pelvic Packing
- Where
- Spain
- Sponsor
- Nuria Llorach-Perucho
Fluid Responsiveness Predictability
Hemodynamic Response to the End-expiratory Occlusion Test to Titrate Fluid Challenge in Operating Room.
Personalzing intraoperative anesthetic fluid management may help in preventing fluid accumulation and related complications. Fluids are gine as boluses in operating room (the so-called FC).
- Trial name
- FC_EEOT (NCT06627907)
- Testing
- fluid challenge, end-expiratory occlusion test
- Volunteers
- 300 people
- Sponsor
- Humanitas Clinical and Research Center
Coronary Artery Disease, Heart Failure With Reduced Ejection Fraction
Resistance Training in Cardiovascular Disease Patients
In this study coronary artery disease patients and patients with heart failure will be randomly assigned to three training groups: combined aerobic interval training with high intensity resistance training, combined aerobic…
- Trial name
- RT in CVD (NCT04638764)
- Testing
- Aerobic interval training combined with high intensity resistance training, Aerobic interval training combined with low intensity resistance training, Aerobic interval training
- Where
- Slovenia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- General Hospital Murska Sobota
Perioperative Care, Hemodynamics
ImPortance of Arterial Measurement Sites (IPAMS) on Intraoperative Hemodynamic Management
The goal of this clinical trial is to demonstrate the importance of arterial pressure measurement sites during major abdominal surgeries.
- Conditions
- Perioperative Care, Hemodynamics, Monitoring Blood Pressure, Arterial Lines
- Trial name
- IPAMS (NCT06982001)
- Testing
- Brachial line guided hemodynamic management, Radial line guided hemodynamic management, Radial line catheterization
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Congestion, Heart Failure
Portal Vein Flow Variability to Quantify Right-Sided Hemodynamic Congestion (PORTAL)
This study evaluates the accuracy of a comprehensive venous Doppler echography including the portal vein pulsatility index (PVPI) to quantify invasively measured right-sided venous pressures.
- Conditions
- Congestion, Heart Failure, Right Heart Catheterisation, Central Venous Pressure
- Trial name
- PORTAL (NCT05411263)
- Testing
- Comprehensive transthoracic echocardiography, Doppler echography & Kino-cardiograph (Kino)
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Vrije Universiteit Brussel
Pediatric Shock
Functional Hemodynamic Assessment in Shocked Patients in the Pediatric Intensive Care Unit
is to assess Functional hemodynamic status in shocked patients in the Pediatric Intensive Care Unit
- Trial name
- NCT06720493
- Testing
- echocardiographic assessment of shocked patients to fluid administration
- Volunteers
- 129 people
- Sponsor
- Assiut University