Clinical trials: Hemodynamic Instability
Hemorrhage, Hemodynamic Instability
Consortium for Optimized Integration of Bio-Artificial Blood Components for Adaptive Resuscitation Therapy
There is need for a whole blood analog for use when banked blood is unavailable or undesirable. In civilian trauma, hemorrhage accounts for ~ 35% of pre-hospital deaths; moreover, ~ 20% of military casualties are in hemorrhagic…
- Trial name
- CONCERT (NCT05756426)
- Testing
- Prospective
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Hemorrhagic Shock
Development of an Algorithm for Prediction of Onset of Hemodynamic Instability in Humans
The purpose for this study is to measure the physiology of human undergoing a Lower Body Negative Pressure usea non-invasive low-power optical technique, near-infrared diffuse optical spectroscopy measurement and compare these…
- Trial name
- NCT00581204
- Testing
- Near-Infrared Diffuse Optical Spectroscopy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hemodynamics Instability, Prone Position
Hemodynamic Changes Due to Prone Position
Perioperative prone position may be associated with hemodynamic instability. The causes of instability have not yet been precisely elucidated.
- Trial name
- NCT04491331
- Testing
- prone position
- Where
- Czechia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Hradec Kralove
HIE, TBI (Traumatic Brain Injury)
Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)
This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different…
- Conditions
- HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability
- Trial name
- ICHOR 1 (NCT06195345)
- Testing
- MR Imaging
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Cesarean Section, Hemodynamic Instability
Low-Doses Of Isobaric Bupivacaine On Intraoperative Hemodynamics In Spinal Anesthesia During Cesarean Section
The primary aim of this study was to compare the effects of two different low-dose bupivacaine used in spinal anesthesia on intraoperative hemodynamics in cesarean section operations.Investigators think that low-dose bupivacaine…
- Trial name
- NCT05136040
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Shoulder Injuries, Anesthesia
The Effects of Preloading Before Beach Chair Position
The main objective of this study is whether preloading before positioning would be effective for less hemodynamic instability. The study also analyzes that patients with preloading will decrease postoperative nausea and vomiting…
- Conditions
- Shoulder Injuries, Anesthesia, Hemodynamic Instability
- Trial name
- NCT04671537
- Testing
- Preloading with crystalloid fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Acupressure, Pain
The Effect of Acupressure After Angiography on Pain Level and Hemodynamic Variables
This randomized controlled study evaluates the effect of acupressure application on the pain level patients after angioography. The hypothesis of this study is that acupressure reduces pain levels and stabilizes hemodynamic…
- Conditions
- Acupressure, Pain, Hemodynamic Instability, Angiopathy, Peripheral
- Trial name
- Acupress (NCT05486533)
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Mersin University
Hemodynamic Instability, Pain
Evaluation in 15 Participants of Blood Flow, Comfort and Efficiency, Using 1 vs 36 Hz Stimulation Via Textile Electrodes
Muscle contractions induced by calf low-intensity neuromuscular electrical stimulation (C-LI-NMES) can increase venous return and may reduce venous thromboembolism.
- Trial name
- TTE_PVV_1_36 (NCT06082297)
- Testing
- Chattanooga Physio, DJO, neuromuscular electrical stimulation
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Anxiety, Hemodynamic Instability
Effect of Acupressure Applied Before Cystectomy on Preoperative Anxiety Level
This randomized controlled study evaluates the effect of acupressure application on the anxiety level patients undergoing cystectomy surgery.
- Trial name
- NCT05325307
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Post-operative Pain, Narcotics Consumption
The Efficacy of Scalp Block in Craniotomy
The aim of the study is to compare the effectiveness and safety of scalp block versus intravenous fentanyl in pain control intraoperatively in craniotomy patients.
- Conditions
- Post-operative Pain, Narcotics Consumption, Pain Assessment, Intraoperative Hemodynamic Instability
- Trial name
- NCT06951230
- Testing
- Fentanyl injection, scalp block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hemodynamic Instability
Effect of Intravenous Ketamine Infusion for Hemodynamic Stability in Patients Undergoing Caesarean Delivery.
Hypotension is the most frequent side effect of intrathecal anesthesia, with a found incidence of more than 80%. With a frequency of between 40% and 60% in patients undergoing surgery, Perioperative shivering is a serious…
- Trial name
- NCT05865080
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hemodynamic Instability
Effects of the Breath Stacking Technic in Healthy Individuals
This study aims to Analyze and compere the hemodynamic and respiratory variables before, during and after the applying of technic as well as evaluate respiratory pressures generated during applying of this same technic and…
- Trial name
- NCT03042403
- Testing
- Breath stacking
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Hypovolemia, Hemodynamic Instability
Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia
To monitor the changes in central and peripheral monitors/waveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.
- Trial name
- LBPN (NCT03592290)
- Testing
- Lower body negative pressure
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Pregnancy Related, Cardiac Output, High
Non-invasive Haemodynamic Monitoring in Pregnancy
This prospective and observational trial over 55 pregnant women (third trimester) compares non invasive haemodynamic monitoring using Nexfin technology and ultrasonography technic
- Conditions
- Pregnancy Related, Cardiac Output, High, Haemodynamic Instability
- Trial name
- NCT03046784
- Testing
- haemodynamic evaluation
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hospital Nord
Triage, Emergency Medical Services
Clinical Predictors of Capillary Refill Time and Their Association With Triage Categories
This observational study aims to determine the correlation between capillary refill time (CRT) and vital parameters in patients presenting to the emergency department.
- Conditions
- Triage, Emergency Medical Services, Vital Signs Monitoring, Hypoperfusion
- Trial name
- CRT_TriageER (NCT07054151)
- Testing
- No clinical intervention (observational study only)
- Where
- Turkey (Türkiye)
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Orthopedic Disorder, Hemodynamic Instability
Evaluating The Cardiovascular Effects of Tourniquet Application
The goal of this prospective observational study is to investigate the impact of tourniquet application on cardiac efficiency through the cardiac cycle efficiency parameter and to explore how central regional technique alters…
- Trial name
- NCT06158165
- Testing
- Mostcare (Vytech, Vygon, Padua, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Merve Şeker
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Hypotension and Shock
Measurement of Hemodynamic Responses to Lower Body Negative Pressure
This study will be collecting data on participants undergoing lower body negative pressure (LBNP) to simulate progressive blood loss.
- Trial name
- LBNP (NCT03582501)
- Testing
- Lower body negative pressure
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hemodynamic Instability, Tracheal Intubation
Attenuation Of Hemodynamic Response To Laryngoscopy. Role Of Dexmedetomidine. A Dose Finding Study
Two doses of Dexmedetomidine (0.5 µ/kg and 0.75 µ/kg) will be used to attenuate the stress response to laryngoscopy in American Society of Anesthesiology, physical class I patients which will be compared with the…
- Conditions
- Hemodynamic Instability, Tracheal Intubation, Dexmedetomidine
- Trial name
- NCT05909215
- Testing
- Normal saline, Dexmedetomidine 0.5 microgram/kg, Dexmedetomidine 0.75 microgram/kg
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation