Clinical trials: Hemodynamic Management
Hemodynamic
Three Different GHDT ( Goal Hemodynamic Directed Therapy) Strategies for Intraoperative Fluid Management Optimization During Major Abdominal Surgery: A Randomized Controlled Trial
Major oncological surgery is among the most complex procedures, involving patients with a combination of high-risk factors that can significantly influence immediate postoperative outcomes and quality of life.
- Trial name
- SMART FLUID (NCT06871150)
- Testing
- Flotrac sensor, HPI, HPI-AFM
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- ASST Sette Laghi
Orthopedic Disorder, Hemodynamic Instability
Hypotension Prediction Index Based Perioperative Protocolized Hemodynamic Management in Geriatric Orthopedic Surgery
Blood pressure optimization has been considered as a crucial factor to avoid perioperative vital organ hypoperfusion, and perioperative hypotension has been addressed as a risk factor for complications and adverse clinical…
- Trial name
- NCT05274412
- Testing
- hypotension prediction index(HPI), ordinary goal-directed hemodynamic therapy
- Where
- Taiwan
- Volunteers
- 280 people
- Sponsor
- National Taiwan University Hospital
Liver Transplantation, End-stage Liver Disease (ESLD)
Restrictive Fluid Management In Liver Transplantation (REFIL) - Pilot
Hypothesis: A Canadian multicentre clinical trial is feasible. Study Design: Multicenter internal pilot parallel arm randomized controlled trial.
- Trial name
- REFIL-1 (NCT05647733)
- Testing
- Low splanchnic blood volume restrictive fluid management strategy, Optimized cardiac output liberal fluid management strategy, Phlebotomy
- Where
- 4 sites in Canada
- Volunteers
- 138 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Perioperative Fluid Management
Comparison of Hemodynamic Results of Two Different Fluid Managements
In the reduction mammoplasty operations performed in the Plastic and Reconstructive surgery operating room in our clinic, the female patient group, who does not have co-morbidities and does not exceed middle age, is followed by…
- Trial name
- NCT05733403
- Testing
- isotonic solution, Noradrenaline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Supine Hypotensive Syndrome
Hemodynamic Management in Women With SHS
Supine hypotensive syndrome often occurs following spinal anesthesia for cesarean delivery.In our study we base the regulation and drug administration both on the regular monitor and on a novel monitor which reflects upon the…
- Trial name
- NCT05341362
- Testing
- LiDCOrapid
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China Medical University, China
Elective Surgery, General Anesthesia
Comparison of Tracheal Intubation in Ramp vs Sniffing Position Using Customized vs Fixed Pillow
The goal of this clinical trial is to find out whether the ramp position or sniffing position is better for endo tracheal intubation which provides better hemodynamic stability and short intubation time and good laryngoscopic…
- Trial name
- NCT07506655
- Testing
- Group A - Fixed Pillow, Group B - Customized Pillow
- Where
- Pakistan
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Intubation, Anesthesia
Comparative Efficacy of Intravenous Labetalol and Lignocaine in Mitigating Hemodynamic Responses to Laryngoscopy During Laparoscopic Cholecystectomy
Laryngoscopy and intubation during laparoscopic cholecystectomy often cause sudden increases in heart rate and blood pressure, which can be harmful in some patients.
- Conditions
- Intubation, Anesthesia, Laparoscopic Cholecystectomy, Hemodynamic Response to Laryngoscopy
- Trial name
- LAB-LIG RCT (NCT07192081)
- Testing
- Labetalol, Lignocaine
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Dr. Waseem Ullah
Electroencephalography, Craniotomy Surgery
Evaluation of Response to Pain From Skull Pin Fixation in Craniotomies
The goal of this observational study is to investigate the relationship between the response to skull pin fixation pain and the analysis of blood pressure, heart rate, and brain wave activity in adults undergoing brain surgery.
- Conditions
- Electroencephalography, Craniotomy Surgery, Pain Management
- Trial name
- NCT06811701
- Testing
- Scalp nerve block, Opioid Anesthetics, Local Anesthetic Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Heart Failure, Heart Failure, Systolic
Hemodynamic-GUIDEd Management of Heart Failure
The GUIDE-HF IDE clinical trial is intended to demonstrate the effectiveness of the CardioMEMS™ HF System in an expanded patient population including heart failure (HF) patients outside of the present indication, but at risk for…
- Conditions
- Heart Failure, Heart Failure, Systolic, Heart Failure, Diastolic, Heart Failure NYHA Class II
- Trial name
- GUIDE-HF (NCT03387813)
- Testing
- CardioMEMS™ HF System
- Where
- 129 sites in United States, Canada
- Volunteers
- 2,358 people
- Sponsor
- Abbott Medical Devices
USCOM, Echocardiography
Comparison of the Ultrasonic Cardiac Output Monitor and Echocardiography for Hemodynamic Assessment in Pediatric Anesthesia
This prospective observational pilot study evaluates agreement between Ultrasound Cardiac Output Monitor (USCOM) measurements and transthoracic echocardiography-derived hemodynamic parameters in pediatric patients under…
- Conditions
- USCOM, Echocardiography, Echocardiography Guided Fluid Management
- Trial name
- NCT07342842
- Testing
- USCOM, Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Sepsis With Hemodynamic Instability
Correlation of Aortic Versus Pulmonary ITV in Response to Vascular Filling
This is a multicenter study conducted in the emergency department of the Nantes University Hospital and the Confluent Private Hospital, over a period of 5 months, based on hemodynamic ultrasound.
- Trial name
- CIAOP (NCT04899323)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Nantes University Hospital
Goal-Directed Fluid Therapy, Hemodynamic Monitoring
Comparison of Goal-directed and Liberal Fluid Management
Background: The investigators aim is to indicate that the "goal directed fluid management" is more effective for open abdominal surgeries by performing perioperative hemodynamic monitorisation using a minimal invasive pulse…
- Conditions
- Goal-Directed Fluid Therapy, Hemodynamic Monitoring, Fluid Management
- Trial name
- NCT04265014
- Testing
- Goal-directed fluid treatment, Liberal Fluid Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Uterine Bleeding, Uterine Neoplasms
Anterior Quadratus Lumborum Block as a Component of Multimodal Analgesia for Abdominal Hysterectomies
The main goal of this randomised double-blinded controlled trial is to assess whether adding anterior quadratus lumborum block preoperatively can reduce intraoperative and postoperative opioid consumption, reduce pain after…
- Conditions
- Uterine Bleeding, Uterine Neoplasms, Uterine Diseases, Uterine Fibroids
- Trial name
- NCT07046949
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, Parenteral administration of analgesics, General Anesthesia (GA)
- Where
- Ukraine
- Volunteers
- 56 people
- Sponsor
- Yuri Semenyuk Rivne Regional Clinical Hospital
Coronary Arterial Disease (CAD)
Combined Coronary CT Angiography and CT Perfusion in Coronary Artery Disease (CoroFusion)
Coronary computed tomography angiography (CTA) provides high-resolution imaging of coronary artery disease (CAD), revealing stenosis, plaque characteristics, and hemodynamic markers like CT-derived fractional flow reserve…
- Trial name
- NCT06949150
- Testing
- coronary angiography, Medical therapy
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Epidural Anesthesia, Ropivacaine Concentration
Effects of Epidurally Administered Ropivacaine Concentration on the Hemodynamic Parameters
In this trial, the investigators intend to examine whether the concentration of local anesthetics during epidural analgesia could be modulating factor for change of hemodynamics in patients undergoing major upper abdominal…
- Conditions
- Epidural Anesthesia, Ropivacaine Concentration, Hemodynamics
- Trial name
- PNU (NCT01559285)
- Testing
- 0.75% ropivacaine concentration, 0.375% ropivacaine concentration, 0.2% ropivacaine concentration
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Pusan National University Hospital
Arthroplasty, Replacement, Hip, Anesthesia, Spinal
Goal Directed Fluid Therapy Versus Liberal Fluid Regimen in Primary Elective Hip Artrhoplasty
Patients undergoing elective primary total hip replacement and spinal anesthesia may encounter significant hemodynamic instability.
- Conditions
- Arthroplasty, Replacement, Hip, Anesthesia, Spinal, Hemodynamic Monitoring, Crystalloid Solutions
- Trial name
- NCT04996420
- Testing
- Clearsight non invasive hemodynamic monitoring
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Nephrectomy, Nephroureterectomy
Goal-directed Hemodynamic Management and Kidney Injury After Radical Nephrectomy or Nephroureterectomy
Radical nephrectomy and nephroureterectomy are common operations for the treatment of renal cell carcinoma and upper tract urothelial carcinoma, respectively. However, acute kidney injury frequently occurs after surgery.
- Conditions
- Nephrectomy, Nephroureterectomy, Hemodynamic Management, Acute Kidney Injury
- Trial name
- NCT05149196
- Testing
- Targeted hemodynamic management, Routine care
- Where
- China
- Volunteers
- 1,724 people
- Sponsor
- Peking University First Hospital
Hemodynamic Instability
Patient Management During Major Abdominal Surgery: an Oxygen Consumption Protocol Compared to Standard Approach
This study compares the actual standard of care with a new protocol to guide hemodynamic optimization during major abdominal surgery, which is more tailored on patient real needs.
- Trial name
- HEART-CORE (NCT03113435)
- Testing
- Oxygen consumption optimization
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Septic Shock, Sepsis
Delphi Septic Shock: Sub-phenotypes Using Point-of-Care Ultrasound in Patients With Septic Shock
The Delphi survey process is a well-established mechanism for generating consensus on a certain topic by using a panel "collective intelligence".
- Conditions
- Septic Shock, Sepsis, Shock
- Trial name
- NCT07616817
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Albany Medical College
Cesarean Section Complications, Hemodynamic Instability
Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.
Prospective, randomized and controlled study who will be conducted at Maisonneuve-Rosemont hospital with the following objectives: To determine if an infusion of carbetocin over 10 minutes will reduce hemodynamic side effects…
- Trial name
- NCT03404544
- Testing
- Carbetocin bolus, Carbetocin infusion
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal