Clinical trials: Hemodynamic and Respiratory Stability
Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure)
SvO2 Trigger in Transfusion Strategy After Cardiac Surgery
Current international guidelines suggest a restrictive transfusion strategy, setting that Hb level at 7 g/dl is a reasonable threshold.
- Conditions
- Undergoing Nonemergent Cardiac Surgery, Central Venous Catheter on the Superior Vena Cava (to Perform ScVO2 Measure), Anemia (<9g/dL) Requiring Blood Transfusion, Hemodynamic and Respiratory Stability
- Trial name
- ReTSEACS (NCT02761564)
- Testing
- Red blood cell tranfusion, ScvO2 measure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Adult Patients Ventilated More Than 48 h, Stable Respiratory and Hemodynamic Conditions for SBT
Pulmonary and Cardiac Ultrasound During Weaning From Mechanical Ventilation
Prospective observational clinical multicentric study in ICU with ventilated patients requiring chest ultrasound analysis.
- Conditions
- Adult Patients Ventilated More Than 48 h, Stable Respiratory and Hemodynamic Conditions for SBT, Consent of Patients, Arterial Line
- Trial name
- PULCO (NCT01098773)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Collapsed Lung, Hemodynamic Stability
Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular Function
The aim of this study is to evaluate the role of nitric oxide on pulmonary vasculature and right ventricular function in postoperative cardiac surgery patients.
- Trial name
- NCT06097026
- Testing
- Alveolar recruitment maneuver, Nitric Oxide
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Fernando Suarez Sipmann
Hypertension, Pulmonary
Interaction Study in Patients With Pulmonary Hypertension and Stable Treatment of Sildenafil 20 mg TID
This study is to demonstrate the safety, tolerability, pharmakokinetic and pharmacodynamic effect of BAY63-2521 in patients with pulmonary hypertension and stable treatment of sildenafil 20 mg.
- Trial name
- NCT00680654
- Testing
- Riociguat (Adempas, BAY63-2521)
- Where
- 5 sites in Germany
- Volunteers
- 7 people
- Sponsor
- Bayer
Adult Patients Ventilated More Than 48 h, Stable Respiratory and Hemodynamic Conditions for SBT
Nasal Humidified High Flow Oxygen During Weaning From Mechanical Ventilation : Ultrasonography Study
This is a prospective, randomized clinical multicentric study in ICU (Intensive Care University)during weaning from mechanical ventilation.
- Conditions
- Adult Patients Ventilated More Than 48 h, Stable Respiratory and Hemodynamic Conditions for SBT, Consent of Patients, Arterial Line
- Trial name
- HiFloLUS (NCT01702779)
- Testing
- mechanical ventilation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sedation
Pharmacokinetic of Sevoflurane During a 48h Sedation in Intensive Care Unit With AnaConDa®
This is a prospective clinical monocentric study in ICU with sedated ventilated patients with sevoflurane during 48 h with the AnaConda® system, establishing pharmacokinetic model of sevoflurane.
- Trial name
- Anaconda (NCT01196754)
- Testing
- sevoflurane
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemodynamic Stability, Pulmonary Diseases or Conditions
A Study Comparing Sevoflurane and Propofol in Patients Undergoing Endobronchial Ultrasound Guided Needle Aspiration
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used to obtain samples from mediastinal and hilar lymph nodes or lung parenchymal lesions for diagnostic and staging…
- Conditions
- Hemodynamic Stability, Pulmonary Diseases or Conditions, Complication of Anesthesia
- Trial name
- NCT07338578
- Testing
- propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi
Spinal Stenosis, Lumbosacral Region
Stability Comparison of TIVA and Sevoflurane in Prone Spinal Surgery(TIVA:Total Intravenous Anesthesia)
Key Points: 1. Objective: o To compare the effects of Total Intravenous Anesthesia (TIVA) and sevoflurane anesthesia on respiratory mechanics, hemodynamic parameters, and neuromonitoring during prone position spinal surgeries. 2.
- Trial name
- TIVA (NCT06558695)
- Testing
- Sevoflurane, TIVA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete