Clinical trials: Hemodynamics
Noninvasive Cardiac Monitoring
Monitoring Blood Flow and Breathing Using a New Device (RFII) Compared to the Gold Standard Device in Post Operative Cardiac Patients
The purpose of this study will be to compare standard of care invasive methods to an FDA approved non-invasive device and a novel wireless non-invasive device, both manufactured by Non-Invasive Medical Technologies Inc., with the…
- Trial name
- NCT01434771
- Sponsor
- University of Florida
Anesthesia, Hemodynamic Instability
Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
The purpose of this study is to compare the risk of hypotension following induction of anesthesia in high-risk patients (American Society of Anesthesiologists risk scores III and IV) using target-controlled infusion (TCI) of…
- Trial name
- NCT06535230
- Testing
- Manual anesthesia induction, Anesthesia induction with Target controlled infusions (TCI), Hemodynamic monitoring with pressure recording analytical method (PRAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Acibadem University
Adrenal Suppression, Hemodynamic Instability
THe Comparison of Target Controlled Infusion of Propofol or Etomidate at General Anesthesia in Geriatric Patients
Compare the efficacy and safety of closed-loop target controlled infusion of propofol or etomidate at general anesthesia in geriatric patients
- Trial name
- NCT02111265
- Testing
- Remifentanil, Cisatracurium, Sufentanil
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Hemorrhagic Shock, Pediatric Trauma
Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients
Pediatric trauma often leads to hemorrhagic shock, which reduces blood flow to the digestive tract and delays gastric emptying. This delay can cause fluid and food to remain in the stomach, increasing the risk of pulmonary…
- Conditions
- Hemorrhagic Shock, Pediatric Trauma, Delayed Gastric Emptying, Gastric Dysmotility
- Trial name
- NCT07810907
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hemodynamics Instability, Arrhythmias Cardiac
Low and Moderete Flow Anaesthesia on Haemodynamics
The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.
- Conditions
- Hemodynamics Instability, Arrhythmias Cardiac, Cerebral Oxygenation
- Trial name
- NCT06871371
- Testing
- Sevoflurane (Volatile Anesthetic), low- medium flow anesthetic machine
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Umraniye Education and Research Hospital
DVT Prevention, Ventilated Patients
ActiveCare+SFT Hemodynamic Profile Compare to SCD Express in Ventilated Patients
Purpose: To test the hemodynamic profile generated by the MCS's ActiveCare+SFT device in ventilated patients and compare it to that of the Kendall SCD Express. Design: Comparative, prospective study.
- Trial name
- NCT00338819
- Sponsor
- Tel-Aviv Sourasky Medical Center
Multiple Trauma, Polytrauma
Development and Internal Validation of a Multimodal Prediction Score for Early Hemodynamic Deterioration in Adult Polytrauma Patients
Severe traumatic injury involving multiple body regions (polytrauma) carries a high risk of rapid bleeding, tissue hypoperfusion, and circulatory collapse.
- Conditions
- Multiple Trauma, Polytrauma, Hemodynamic Instability, Traumatic Shock
- Trial name
- NCT07850427
- Volunteers
- 300 people
- Sponsor
- Assiut University
Major Depressive Disorder, Bipolar Disorder
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
The purpose of this research is to measure brain activity in individuals with mood disorders and memory problems using a simple, safe, and noninvasive method called functional near-infrared spectroscopy (fNIRS).
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mild Cognitive Impairment
- Trial name
- NCT06897670
- Testing
- Observational assessment using functional near-infrared spectroscopy (fNIRS), a noninvasive, portable brain imaging tool that measures changes in brain blood flow and oxygen levels.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Circulatory Shock, Hemodynamic Instability
Peripheral pULSe Assessment and Arterial pRessure (PULSAR)
This prospective multicenter observational study aims to investigate the relationship between palpable peripheral pulses and simultaneously measured arterial blood pressure in adult patients with circulatory shock or impending…
- Conditions
- Circulatory Shock, Hemodynamic Instability, Hypotension, Shock
- Trial name
- PULSAR (NCT07609095)
- Testing
- Peripheral Pulse Palpation
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Region Stockholm
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPH
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are severe clinical conditions that, despite advances in therapeutics over the past 20 years, lead to serious morbidity and…
- Trial name
- NCT05618093
- Testing
- Non-invasive hemodynamic measurements
- Where
- United States
- Sponsor
- University of California, Los Angeles
Intracranial Atherosclerosis ICAS, Hemodynamic
Digital Angiography-Derived Fractional Flow Assessment for Intracranial Stenosis
The goal of this observational study is to learn whether a digital angiography derived fractional flow reserve (DPR) measurement can improve the prediction of stroke risk in adults with symptomatic intracranial atherosclerotic…
- Conditions
- Intracranial Atherosclerosis ICAS, Hemodynamic, Stroke
- Trial name
- CASSISS-DPR (NCT07309705)
- Testing
- Standardized medical therapy targeting vascular risk factors and stroke prevention
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xuanwu Hospital, Beijing
Sleep, Athletic Performance
Sleeping Habits on Performance Following Sleep Deprivation
The goal of this randomized crossover clinical trial is to determine if habitual sleeping habits can predict endurance performance following a night of partial sleep deprivation in healthy untrained, recreationally trained, and…
- Conditions
- Sleep, Athletic Performance, Hemodynamics
- Trial name
- NCT05942664
- Testing
- Sleep
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Vasoplegic Syndrome of Cardiac Surgery
Mic Mac: Micro- and Macrocirculatory Assessment During Cardiac Surgery in Patients at Risk of Vasoplegic Syndrome: A Prospective Study.
This research focuses on understanding the vasoplegic syndrome after cardiac surgery under extracorporeal circulation and in the aftermath of your surgery in the ICU.
- Trial name
- MicMac (NCT07059715)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- European Georges Pompidou Hospital
Glioblastoma
Multicentre Validation of How Vascular Biomarkers From Tumor Can Predict the Survival of the Patient With Glioblastoma
Despite an aggressive therapeutic approach, the prognosis for most patients with glioblastoma (GBM) remains poor. The relationship between non-invasive Magnetic Resonance Imaging (MRI) biomarkers at preoperative, postradiotherapy…
- Trial name
- ONCOhabitats (NCT03439332)
- Where
- Spain
- Volunteers
- 305 people
- Sponsor
- Juan M Garcia-Gomez
Stroke, Acute
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
- Trial name
- NCT04051658
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Collapsed Lung, Hemodynamic Stability
Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular Function
The aim of this study is to evaluate the role of nitric oxide on pulmonary vasculature and right ventricular function in postoperative cardiac surgery patients.
- Trial name
- NCT06097026
- Testing
- Alveolar recruitment maneuver, Nitric Oxide
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Fernando Suarez Sipmann
CHF, Renal Disease
Validation of a Sensor for Non-Invasive Measurements
Subjects will be measured with both a sensor and a reference device
- Conditions
- CHF, Renal Disease, Hypertension
- Trial name
- NCT03463148
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Baxter Healthcare Corporation
Fontan Palliation
Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan Physiology
The purpose of this study is to find out more about the effectiveness of Tadalafil in improving hemodynamic capabilities, endothelial function, and end-organ function in patients who have previously undergone a Fontan Palliation.
- Trial name
- NCT05206955
- Testing
- Tadalafil
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Mayo Clinic
Radical Cystectomy, Perioperative Complications
Advanced Hemodynamic Monitoring for Goal-directed Hemodynamic Management During Radical Cystectomy
The purpose of this study is to determine whether increasing cardiac output by a combination of intravenous fluids and inotropic drugs can reduce mortality and morbidity in radical cystectomy operations.
- Conditions
- Radical Cystectomy, Perioperative Complications, Hemodynamic Monitoring
- Trial name
- NCT00966147
- Testing
- Increasing oxygen delivery .
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Shock, Acute Circulatory Failure
Concordance Study of Therapeutic Decision-making in Patients With Shock Based on Hemodynamic Monitoring
Shock is a serious complication corresponding to acute circulatory failure resulting in multiorgan failure and death. In order to improve cellular oxygen utilization, several therapies can be used.
- Conditions
- Shock, Acute Circulatory Failure, Hemodynamic Monitoring
- Trial name
- PICC-ECHO (NCT05613647)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
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