Clinical trials: Hemodynamics Instability
Orthopedic Disorder, Hemodynamic Instability
Evaluating The Cardiovascular Effects of Tourniquet Application
The goal of this prospective observational study is to investigate the impact of tourniquet application on cardiac efficiency through the cardiac cycle efficiency parameter and to explore how central regional technique alters…
- Trial name
- NCT06158165
- Testing
- Mostcare (Vytech, Vygon, Padua, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Merve Şeker
Shoulder Injuries, Anesthesia
The Effects of Preloading Before Beach Chair Position
The main objective of this study is whether preloading before positioning would be effective for less hemodynamic instability. The study also analyzes that patients with preloading will decrease postoperative nausea and vomiting…
- Conditions
- Shoulder Injuries, Anesthesia, Hemodynamic Instability
- Trial name
- NCT04671537
- Testing
- Preloading with crystalloid fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hemodynamic Instability
Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery
Direct laryngoscopy (DL) procedure is typically done under general anaesthesia as a day case. It is a short but irritating.Various drugs and drug combinations have been used to attenuate stress response to DL.Administrating…
- Trial name
- NCT04659057
- Testing
- Nebulized Lidocaine, Nebulized dexmedetomidine, Nebulized lidocaine and dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Central Venous Pressure, Hepatectomy
Preoperative Sildenafil Administration for Hepatectomy
Hepatectomy is an important treatment for liver diseases, and bleeding is one of the most common complications during dissection of the liver parenchyma.
- Conditions
- Central Venous Pressure, Hepatectomy, Hemodynamics Instability, Sildenafil
- Trial name
- NCT06237751
- Testing
- Sildenafil 100 MG
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Vascular Remodeling, Sedentary Behavior
Effect of Training Intensity on Microvascular Function
The aim of this trial is to investigate the effect of aerobic training intensity on muscle vascular function: continuous versus interval.
- Conditions
- Vascular Remodeling, Sedentary Behavior, Hemodynamic Rebound
- Trial name
- NCT07237854
- Testing
- Percutaneous muscle biopsies of the vastus lateralis (quadriceps), Measurement of the maximal oxygen uptake (VO2max), Non-Invasive Cardiac Output Measurement (Innocor)
- Where
- Belgium
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Hemodynamic Instability
The Effects of Lidocaine and Esmolol on Attenuation of Hemodynamic Response to Orotracheal Intubation
The present study aims to compare the hemodynamic response during laryngoscopy and orotracheal intubation using continuous infusion of lidocaine and esmolol in patients undergoing general anesthesia.
- Trial name
- NCT03612492
- Testing
- Esmolol, Lidocaine
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital de Base
Hypertension, Hemodynamic Instability
Perioperative Baroreflex Sensitivity
Impaired baroreflex sensitivity (BRS) is a marker of autonomous dysfunction, which may play an important role in the long-term development of hypertension.
- Conditions
- Hypertension, Hemodynamic Instability, Surgery
- Trial name
- NCT02435875
- Testing
- no intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Hemodynamic Instability, Intubation Complication
Effect-site Concentration of Remifentanil for Double-lumen Tubes Intubation: Airtraq VS Macintosh Laryngoscope
The 50% effective concentration of remifentanil by target controlled infusion was not determined for inhibiting the haemodynamic response during double-lumen tube (DLT) intubation.
- Trial name
- NCT03653910
- Testing
- Airtraq, Macintosh
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Hemodynamic Instability
The Bolus Dose of Dexmedetomidine (ED50) That Avoids Hemodynamic Compromise in Children
Dexmedetomidine is a sedative drug that has many benefits when given to children under anesthesia, such as improved pain relief and reduced agitation following their surgery.
- Trial name
- DexMED (NCT01498380)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hemodynamic Instability and Shivering
Comparative Study Between Intravenous Granisetron and Ondansetron on Their Effect on Hemodynamics and Shivering After Spinal Anesthesia in Elective Cesarean Delivery
Spinal anesthesia is commonly used in cesarean section surgeries . The most important adverse effects of spinal anesthesia are hypotension and bradycardia caused by sympathetic blockade, with an incidence of about 55-100% .
- Trial name
- NCT06437236
- Testing
- ondansetron, granisetron
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Infertility Female, Hemodynamic Instability
Lidocaine vs Magnesium Sulfate for Hemodynamic Stability During Emergence in Infertility-Related Laparoscopic Surgery"
This study is being conducted to compare two medications, intravenous lidocaine and intravenous magnesium sulfate, and their ability to keep blood pressure and heart rate stable during the period of waking up from general…
- Trial name
- LidoMagGyna (NCT07359560)
- Testing
- Lidocaine (drug), Normal Saline (Intravenous), magnesium sulfate
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Perioperative Complication, Hemodynamic Instability
The Influence of Fasting on Selected Hemodynamic Parameters Measured in a Non-invasive Way
Preoperative fasting is considered to be refraining from taking meals for at least 6 hours and clear fluids for at least 2 hours before anesthesia.
- Trial name
- NCT04972500
- Testing
- Nutricia Pre-op, 400 milliliters, per os
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Hypovolemia, Fluid Loss
Acetated Ringer´s Solution in Experimental Hypovolemia
Intravenous fluids are often given to increase stroke volume and thereby improve global oxygen delivery. The effect is however often transient, but the effect of a fluid bolus on stroke volume and other hemodynamic variables over…
- Conditions
- Hypovolemia, Fluid Loss, Hemodynamic Instability
- Trial name
- Volu-Flow (NCT05705115)
- Testing
- Ringer acetate, Lower body negative pressure
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hypovolemia, Hemodynamic Instability
Hemodynamics Monitoring During Lower Body Negative Pressure (LBNP) Induced Controlled Hypovolemia
To monitor the changes in central and peripheral monitors/waveforms during gradual hypovolemia induced by lower body negative pressure in healthy volunteers.
- Trial name
- LBPN (NCT03592290)
- Testing
- Lower body negative pressure
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yale University
Hemodynamic Instability
Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery
During endoscopic sinus surgery (ESS), epinephrine local injection and controlled hypotension is essential in order to increase the visibility in the operative field and reduce the risk.
- Trial name
- NCT02464722
- Testing
- Dexmedetomidine, Remifentanil, Epinephrine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Hemodynamic Instability
The Cold Fluids Study
In this single center crossover study the aim is to investigate the effect of Ringer's lactate solution at high and low temperatures on physiological response in healthy adults.18 healthy volunteers will be included.
- Trial name
- NCT05610254
- Testing
- Ringer's Lactate
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Hemorrhagic Shock
Development of an Algorithm for Prediction of Onset of Hemodynamic Instability in Humans
The purpose for this study is to measure the physiology of human undergoing a Lower Body Negative Pressure usea non-invasive low-power optical technique, near-infrared diffuse optical spectroscopy measurement and compare these…
- Trial name
- NCT00581204
- Testing
- Near-Infrared Diffuse Optical Spectroscopy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine