Clinical trials: Hemodynamics Instability
Hemodynamic Instability
Study of Ultrasonographic Cava Femoral Ratio in the Critically Ill Patient With Shock
This study aims to describe the ratio of the diameter of inferior vena cava to the common femoral vein measured by ultrasonography in critically ill patients with shock, and to evaluate the potential link between this ratio and…
- Trial name
- ECHO-RCF (NCT02891577)
- Testing
- Ultrasonography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hemodynamic Instability
Effect of Remimazolam and Propofol on Hemodynamic Stability in Prone Position
Most of the major spinal surgeries are performed in the supine position, which causes a decrease in stroke volume and cardiac index, which leads to the occurrence of hypotension during surgery.
- Trial name
- NCT05644483
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Asan Medical Center
Obstruction of Esophagus, Respiratory Complication
Hemodynamic and Respiratory Effects of Esophageal Dilation in Children
The aim of this study compares hemodynamic and respiratory changes and complications in children who undergoing endoscopy for esophageal balloon dilatation and endoscopy for only control.
- Conditions
- Obstruction of Esophagus, Respiratory Complication, Hemodynamic Instability
- Trial name
- NCT02512770
- Testing
- endoscopic dilatation
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Hemodynamic Instability
Scalp Block -Craniotomi
Postoperative pain after craniotomy is an important clinical problem as it can lead to hypertension and increased intracranial pressure.
- Trial name
- scalp block (NCT06264765)
- Testing
- scalp block, Incisional infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Aydin Adnan Menderes University
Renal Function Disorder, Hemodynamic Instability
The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric Patients
The aim of this study is to evaluate the effect of dexmedetomidine infusion on early stage renal function.
- Trial name
- NCT01948336
- Testing
- Dexmedetomidine, Ketamine, Propofol
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal
Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair
The purpose of this study is to compare two intravenous anesthetics, remimazolam and propofol, for their effects on intraoperative hemodynamic stability in patients undergoing thoracic or abdominal endovascular aortic repair.
- Conditions
- Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal, Intraoperative Hypotension, Hemodynamic Instability During Anesthesia
- Trial name
- NCT07806006
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Hypothermia Neonatal, Haemodynamic Instability
Evaluation of Haemodynamic in Neonates Treated With Hypothermia"
Perinatal hypoxia in the form of hypoxic-ischaemic encephalopathy (HIE) is a frequent cause of cerebral impairment in neonates. HIE occurs in 3 to 5 of 1000 neonates in developed countries and is significantly higher in…
- Conditions
- Hypothermia Neonatal, Haemodynamic Instability, Perinatal Asphyxia
- Trial name
- NCT05574855
- Where
- 4 sites in Poland
- Volunteers
- 113 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Cardiac Arrest, Cardiac Arrest Circulatory
Resuscitative TEE Collaborative Registry
The general objective of this study is to evaluate the clinical impact and safety of focused, point-of-care transesophageal echocardiography (TEE) used during the evaluation of critically-ill patients in the emergency and…
- Conditions
- Cardiac Arrest, Cardiac Arrest Circulatory, Cardiac Arrest, Out-Of-Hospital, Shock
- Trial name
- rTEECoRe (NCT04972526)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Pennsylvania
Hemodynamic Instability, Fluid Therapy
Hemodynamic Stability During Induction of Anaesthesia
The study aim is to investigate if preoperative volume bolus based on lean body weight could preserve mean arterial pressure during target controlled infusion of anaesthesia (TCI) or rapid sequence induction of anaesthesia (RSI)…
- Conditions
- Hemodynamic Instability, Fluid Therapy, Anesthesia; Adverse Effect
- Trial name
- NCT03394833
- Testing
- gelofusine
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Intubation Complication, Hemodynamic Instability
Hemodynamic Study With PRAM of the Cardiovascular Response to the Positioning of the Extraglottic Device
The purpose of the study will be to record the hemodynamic response measured by traditional methods (non-invasive blood pressure and ECG) and Pressure Recording Analytical Method in patients undergoing laryngeal mask placement…
- Trial name
- NCT02918526
- Testing
- airway management
- Volunteers
- 94 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Hemodynamic Instability, Surgery
End-expiratory Occlusion Test and Lung Recruitment Maneuver to Assess Fluid responsiVeness In Surgical Patients
The functional hemodynamic test (FHT) called passive leg raising (PLR) has been successfully used for assessing the fluid responsiveness in ICU patients since 2009 and its reliability has been confirmed by three large…
- Conditions
- Hemodynamic Instability, Surgery, Fluid Overload
- Trial name
- ELVIS (NCT03820440)
- Testing
- End-expiratory occlusion test (EEOT), Lung recruitment manovre (LRM)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Humanitas Clinical and Research Center
Effects of Anesthesia Spinal and Epidural in Pregnancy
The Relationship Between Perfusion Index and Pleth Variability Index and Hemodynamics in Spinal Anesthesia
In routine practice, the preferred anesthesia method in cesarean section operations is spinal anesthesia, but it causes hypotension in a significant part of the patients.
- Trial name
- NCT05174260
- Testing
- perfusion index, pleth variable index
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Adiyaman University
Sudden Cardiac Death
Development of Algorithms to Predict Hemodynamic Instability
Hemodynamic monitoring in hospitalized patients is crucial since in clinical practice unexpected deterioration of cardiovascular function remains a serious problem and an important cause of death.
- Trial name
- NCT01262508
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Hypotension, Cesarean Section
"Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section"
Spinal anesthesia-induced hypotension is one of the most frequent and clinically significant complications of obstetric anesthesia, occurring in up to 50-80% of parturients undergoing elective cesarean section.
- Conditions
- Hypotension, Cesarean Section, Hemodynamic Instability, Anxiety, Anticipatory
- Trial name
- BREATHE-CS (NCT07494955)
- Testing
- Mindfulness-Based Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Aysenur Dostbil
Hemodynamic Instability, Postoperative Complications
Continuation of Goal Directed Haemodynamic Optimization in the PACU
Post-operative monitoring of all patients after anaesthesia in the post anaesthesia care unit (PACU) is standard of care today. It helps to reduce morbidity and even mortality in high-risk patients.
- Conditions
- Hemodynamic Instability, Postoperative Complications, Ultrasound Imaging
- Trial name
- NCT04822116
- Testing
- goal directed intraoperative haemodynamic optimization
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Schleswig-Holstein
Hemodynamic Instability
Validation of a New Method to Measure Cardiac Output: Comparison With Thermodilution
Many mini-invasive devices to monitor cardiac output (CO) have been introduced and among them the Pressure Recording Analytical Method (PRAM).
- Trial name
- NCT01806467
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Università Politecnica delle Marche
Propofol, Remimazolam
Respiratory Depression of Remimazolam vs. Propofol for Monitored Anesthesia Care
The comparison of incidence of respiratory depression between remimazolam and propofol under monitored anesthesia care for hysteroscopic surgery
- Conditions
- Propofol, Remimazolam, Hysteroscopic Surgery, Respiratory Insufficiency
- Trial name
- NCT07076628
- Testing
- Propofol, Remimazolam
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- DongGuk University
Hemorrhagic Strokes, Postoperative Hypertension
A Comparison of Nicardipine and Labetalol for Blood Pressure Control in Intensive Care Patients After Hemorrhagic Stroke Brain Surgery
Patients with hemorrhagic stroke who undergo brain surgery (craniotomy) often experience high blood pressure after surgery. Poor blood pressure control can increase the risk of bleeding, brain injury, and other serious…
- Conditions
- Hemorrhagic Strokes, Postoperative Hypertension, Hemodynamic Instability
- Trial name
- NIC-LAB ICU (NCT07364201)
- Testing
- Nicardipine, Labetalol
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Sumatera Utara
Morbid Obesity, Hemodynamic Instability
Effects of Low-Flow Anesthesia on Hemodynamic Parameters and Oxygenation in Morbidly Obese Patients
Low-flow anesthesia has been used for years with positive results, but its effects on hemodynamic parameters and oxygenation are not clearly known in high-risk morbidly obese patients who are prone to pulmonary dysfunction…
- Conditions
- Morbid Obesity, Hemodynamic Instability, Bariatric Surgery Candidate
- Trial name
- Oxygenation (NCT03721536)
- Testing
- hemodynamic parameters, arterial blood gase
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Inonu University
Septic Shock, Hemodynamic Instability
Whether a Minimal Volume Could Predict Fluid Responsiveness Using Thermodilution by PAC in Septic Shock Patients
Assessment of fluid responsiveness (FR) is to detect whether patient could benefit from fluid therapy. Mini fluid challenge has been widely used in clinical practice to prevent patients from volume overload.
- Conditions
- Septic Shock, Hemodynamic Instability, Fluid Therapy
- Trial name
- NCT04515511
- Testing
- 4% gelatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital