Clinical trials: Hemorrhagic Stroke, Intracerebral
Nervous System Diseases, Cerebrovascular Disorders
Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage
MSU-ICH is a prospective, multicenter, Week-wise-randomized, open-label, blinded-endpoint (PROBE) clinical trial comparing ultra-early prehospital blood pressure lowering delivered by a Mobile Stroke Unit (MSU) with standard…
- Conditions
- Nervous System Diseases, Cerebrovascular Disorders, Cardiovascular Diseases, Vascular Diseases
- Trial name
- MSU-ICH (NCT07665827)
- Testing
- Mobile Stroke Unit Management, Standard Management
- Where
- China
- Volunteers
- 706 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Ischemic
A Clinical Study of iNSC Intervent Cerebral Hemorrhagic Stroke
This is a single centre、single arm、open-label，to investigate the safety and efficacy of induction of neural stem cells transplantation in the brain
- Trial name
- NCT03725865
- Testing
- Induction of neural stem cells
- Volunteers
- 12 people
- Sponsor
- Allife Medical Science and Technology Co., Ltd.
Ischemic Stroke, Transient Ischemic Attack
Eliquis Acute Stroke Safety Evaluation
Study Design: This is an investigator-initiated prospective, open label, single arm phase IV study. Patients with documented non-valvular atrial fibrillation (AF) with acute TIA (defined as acute focal neurological deficits, with…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- EASSE (NCT04435418)
- Testing
- Apixaban
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Stroke Acute, Acute Ischemic Stroke AIS
One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy
Stroke, especially acute ischemic stroke (AIS) caused by a blocked blood vessel in the brain, is a leading cause of death and long-term disability.
- Conditions
- Stroke Acute, Acute Ischemic Stroke AIS, Hemorrhagic Stroke, Intracerebral
- Trial name
- GET-FAST (NCT07052045)
- Testing
- One Stop Management, Usual care management
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 390 people
- Sponsor
- Prof. Dr. Jan Liman
Intracerebral Hemorrhage
Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke
The goal of this clinical trial] is to determine if anakinra can ameliorate the formation of perihaematomal oedema in patients with spontaneous intracerebral haemorrhage (ICH).
- Trial name
- ACTION (NCT04834388)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Radboud University Medical Center
Intracerebral Infarcts, Ischemic Stroke
Discharge Educational Strategies for Reduction of Vascular Events
DESERVE is a discharge education study using health workers to enroll and randomly assign 800 subjects diagnosed with TIA, or mild stroke to either risk factor education or usual care.
- Conditions
- Intracerebral Infarcts, Ischemic Stroke, Hemorrhagic Strokes, TIA's
- Trial name
- DESERVE (NCT01836354)
- Testing
- DESERVE education
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- NYU Langone Health
Hemorrhagic Stroke, Intracerebral Hemorrhage
Mesenchymal Stem Cells Therapy in Patients With Recent Intracerebral Hemorrhage
The overall goal of this study is to develop mesenchymal stem cell therapy for treatment of acute spontaneous hemorrhagic stroke.
- Trial name
- NCT03371329
- Testing
- MSC
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Chronic Stable Angina, Unstable Angina
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
The association between alcohol consumption and cardiovascular disease (CVD) has mostly been examined using broad endpoints or cause-specific mortality.
- Conditions
- Chronic Stable Angina, Unstable Angina, Coronary Heart Disease Not Otherwise Specified, Acute Myocardial Infarction
- Trial name
- NCT01864031
- Where
- United Kingdom
- Volunteers
- 2,240,000 people
- Sponsor
- University College, London
Intracerebral Hemorrhage
Insights From the Retina on Cerebral Microvascular Dysfunction in Haemorrhagic Stroke
Fundoscopy, optical coherence tomography (OCT) and OCT-angiography (OCTA) are established examinations and bear minimal risks. The recognition of retinal microvascular signs will enhance the pathophysiological understanding of…
- Trial name
- RETINA-ICH (NCT04363619)
- Testing
- OCT and OCTA
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University of Zurich
Stroke, Chronic Stroke
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.
- Conditions
- Stroke, Chronic Stroke, Intracerebral Haemorrhage, Intracerebral Haemorrhage (ICH)
- Trial name
- PHATHOM (NCT07053917)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Stroke Hemorrhagic, Intracerebral Haemorrhage
Tranexamic Acid for Spontaneous Acute Cerebral Hemorrhage Trial
This study aims to explore the effectiveness of tranexamic acid (also known as trans amine or TXA) in reducing hematoma expansion in patients with hemorrhagic stroke when given in the acute phase.
- Trial name
- TRANSACT (NCT03044184)
- Testing
- Tranexamic Acid
- Where
- Hong Kong
- Volunteers
- 220 people
- Sponsor
- Kwong Wah Hospital
Intracerebral Hemorrhage, Nontraumatic Intracerebral Hemorrhage
Detection of an Endovascular Treatment Target in Patients With an Acute, Spontaneous Intracerebral Hemorrhage
This study is to determine if a treatment target for a potential endovascular therapy exists in patients with an acute, spontaneous (non-traumatic) ICH.
- Trial name
- HemEXPLO (NCT05504941)
- Testing
- Diagnostic, cerebral Digital Subtraction Angiography (DSA)
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Hospital, Basel, Switzerland
Stroke, Acute, Ischemic Stroke
Remote Ischemic Conditioning in Patients With Acute Stroke (RESIST)
Our primary aim is to investigate whether remote ischemic conditioning (RIC) as an adjunctive treatment can improve long-term recovery in acute stroke patients as an adjunct to standard treatment.
- Conditions
- Stroke, Acute, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral Hemorrhage
- Trial name
- RESIST (NCT03481777)
- Testing
- Remote Ischemic Conditioning
- Where
- 4 sites in Denmark
- Volunteers
- 1,500 people
- Sponsor
- Grethe Andersen
Intraventricular Hemorrhage, Intracerebral Hemorrhage
The Natural History of Procalcitonin in Hemorrhagic Stroke
Approximately 12% of strokes in the United States are hemorrhagic.1 Hemorrhagic stroke can lead to multiple complications including fever that is not infectious.
- Trial name
- NCT01498705
- Testing
- Procalcitonin level
- Where
- United States
- Sponsor
- CAMC Health System
Stroke, Ischemic, Tomography, X-Ray Computed
DECT for Differentiating Intracerebral Hemorrhage From Contrast Extravasation
The goal of this clinical trial is to investigate the use of DECT (Dual-Energy Computed Tomography) in patients with acute ischemic stroke who receive an intervention (thrombolysis or thrombectomy).
- Trial name
- DECT-ICH (NCT05675774)
- Testing
- Dual Energy CT
- Where
- Canada
- Volunteers
- 189 people
- Sponsor
- University of Manitoba
Intracerebral Hemorrhage
Recovery and Outcomes From Stroke
The investigators will perform follow-up on 500 cases of deep and lobar intracerebral hemorrhage to perform advanced neuroimaging before 45 days post stroke, and evaluations of motor and cognitive function at baseline, 3 months…
- Trial name
- ROSE (NCT04007757)
- Where
- 8 sites in United States
- Volunteers
- 500 people
- Sponsor
- State University of New York at Buffalo
Intracerebral Hemorrhage, Hemorrhagic Stroke
Outcome Prediction and Recovery After Spontaneous Intracerebral Haemorrhage
Spontaneous intracerebral haemorrhage (ICH) is a severe form of stroke with high mortality and frequent long-term disability. Current tools to predict how an individual patient will recover are limited.
- Trial name
- CR-4-Health (NCT07882784)
- Where
- 3 sites in Austria, Slovenia
- Volunteers
- 300 people
- Sponsor
- University Medical Centre Maribor
Intracerebral Hemorrhage
A Pilot Study of Minocycline in Intracerebral Hemorrhage Patients
The MACH Trial is a pilot study of 400mg minocycline over five days in acute intracerebral hemorrhage patients. The study will evaluation the safety and efficacy of minocycline in intracerebral hemorrhage patients.
- Trial name
- MACH (NCT01805895)
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Augusta University
Stroke, Vascular Accident
PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)
Stroke-associated pneumonia (SAP) is a grave complication of stroke and one of the most important predictors for patients' poor outcomes.
- Conditions
- Stroke, Vascular Accident, Intracranial Hemorrhages, Intracerebral Hemorrhage
- Trial name
- PRO-CHASE (NCT05419193)
- Testing
- Propranolol Hydrochloride, control group
- Where
- 12 sites in China
- Volunteers
- 168 people
- Sponsor
- Beijing Tiantan Hospital
Cavernous Malformations, Intracerebral Hemorrhage
Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot Trial
The aim of this pilot phase trial is to assess the safety and tolerability, and estimate the efficacy of sirolimus in reducing the incidence of ICH during high-risk periods for rebleeding, compared to placebo.
- Conditions
- Cavernous Malformations, Intracerebral Hemorrhage, Brainstem Stroke
- Trial name
- CALM (NCT06091332)
- Testing
- Sirolimus, Starch flake
- Where
- 2 sites in China
- Volunteers
- 75 people
- Sponsor
- Huashan Hospital