Clinical trials: Hemorrhoid Pain
Hemorrhoids, Pain
Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal Hemorrhoids
Rubber band ligation is a simple and effective procedure for the management of hemorrhoidal disease. However, 90% of patients have some degree of discomfort associated with the procedure and up to 40% develop clinically…
- Trial name
- NCT02130830
- Testing
- Topical 2,5% lidocaine + 2,5% prilocaine gel
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Hemorrhoidal Disease, Internal Hemorrhoids
Clinical Outcomes After Laser Hemorrhoidoplasty
This single-center prospective observational study aims to evaluate clinical outcomes, postoperative pain scores, complications, and patient satisfaction in adults undergoing laser hemorrhoidoplasty for symptomatic internal…
- Trial name
- LHP (NCT07520734)
- Testing
- Laser Hemorrhoidoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanliurfa Education and Research Hospital
Hemorrhoid Pain, Haemorrhoid Inflammation
Efficacy and Safety of CONAN® Proctological Cream for Treatment of Haemorrhoidal Disease
Aim of the study is to assess the efficacy, safety and tolerability of CONAN® (Proctological Cream, Medical Device, Omikron Italia Srl) on most frequent symptoms in grade 1-2 of haemorrhoidal disease and anal fissures.
- Trial name
- NCT05984641
- Testing
- CONAN® Proctological Cream
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Omikron Italia S.r.l.
Postoperative Pain, Hemorrhoids Third Degree
Efficacy of Ice Packing Application in Post-Hemorrhoidectomy Recovery
According to the previous study, surgical intervention exhibited significant differences in daily life before and after a hemorrhoidectomy.
- Conditions
- Postoperative Pain, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids
- Trial name
- ICE-HEMO (NCT07186348)
- Testing
- Ice packing, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 429 people
- Sponsor
- Chang Gung Memorial Hospital
Pain Management, Hemorrhoids Third Degree
Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a topical ointment containing two local anesthetics (lidocaine 23% and tetracaine 7%) can reduce pain after hemorrhoid surgery in adults.
- Conditions
- Pain Management, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids Second Degree
- Trial name
- NCT07688031
- Testing
- Lidocaine 23% / Tetracaine 7% topical ointment (compounded)
- Where
- Chile
- Volunteers
- 74 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Hemorrhoidectomy, Hemorrhoids Third Degree
Comparison Study: Ligasure Versus Conventional Hemorrhoidectomy in III and IV Degree Hemorrhoids.
A comparison study was performed between Ligasure and Milligan morgan hemorrhoidectomy to find out the outcome between these two techniques in 3rd and 4th degree hemorrhoids.This advance vessel sealing device is used to seal the…
- Conditions
- Hemorrhoidectomy, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Operative Time
- Trial name
- NCT03848468
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Hemorrhoids, Perioperative Anxiety
Dexmedetomidine vs Tramadol for Anxiety, Pain, and Hemodynamics in Hemorrhoidectomy
This prospective, randomized, double-blind, placebo-controlled trial evaluates whether preoperative intravenous dexmedetomidine or tramadol reduces perioperative anxiety compared with placebo in patients undergoing elective…
- Conditions
- Hemorrhoids, Perioperative Anxiety, Postoperative Pain
- Trial name
- DEXTRA-H (NCT06860100)
- Testing
- Dexmedetomidine, Tramadol, 0.9 % Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Hemorrhoid
Study of Pain Control in Hemorrhoidectomy
Patients will get an injection of either SKY0402 or placebo during hemorrhoid surgery, and their pain and pain medicine use will be monitored.
- Trial name
- NCT00890721
- Testing
- SKY0402
- Where
- Poland
- Volunteers
- 189 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Hemorrhoid
Posthemorrhoidectomy Pain Management With Electronic Bidet or Sitz Bath
The investigator will perform a randomized clinical trials to compare the effect of pain management and wound healing after hemorrhoidectomy between warm sitz bath and electronic bidet.
- Trial name
- NCT02353156
- Testing
- Electronic bidet, Sitz bath
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Hemorrhoids, Postoperative Pain
Pudendal Nerve Block Techniques for Pain Control After Hemorrhoidectomy
Hemorrhoidectomy is frequently associated with severe postoperative pain despite multimodal analgesia. Ultrasound-guided pudendal nerve block has become an effective regional analgesic technique, but it remains unknown whether…
- Trial name
- PINPOINT (NCT07813338)
- Testing
- Transgluteal Pudendal Nerve Block, Transperineal pudendal nerve block
- Volunteers
- 140 people
- Sponsor
- Vinmec Healthcare System
Pain, Acute Post-Operative, Pilonidal Sinus
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.
- Conditions
- Pain, Acute Post-Operative, Pilonidal Sinus, Hemorrhoids, Anesthesia
- Trial name
- NCT06459739
- Testing
- sacral ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Hemorrhoids
Sutureless Hemorrhoidectomy Versus Conventional Ligation in Advanced Hemorrhoids
Hemorrhoidal disease is a frequent benign anorectal ailment in surgical practice. Conventional excisional hemorrhoidectomy using the Milligan-Morgan technique remains effective but is significantly limited by severe postoperative…
- Trial name
- NCT07824999
- Testing
- Energy-based sutureless hemorrhoidectomy, Conventional Milligan-Morgan hemorrhoidectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Hemorrhoids, Postoperative Pain
Cryotherapy Post-haemorrhoidectomy (CYPHER) Randomized Controlled Trial
Haemorrhoids is a common problem with an estimated prevalence of 5 to 36%. Surgery is indicated in patients with grade 3 to 4 piles and in patients whom conservative measures have failed.
- Conditions
- Hemorrhoids, Postoperative Pain, Postoperative Complications, Cryotherapy Effect
- Trial name
- NCT06005727
- Testing
- Transanal ice pack
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Hemorrhoids, Hemorrhoid Pain
Preoperative Micronized Flavonoid Fraction (MFF) Use in Multimodal Anesthesia in Anorectal Surgery
Aim: To assess the efficiency of the micro-flavonoid fraction (MMF) administration prior to anorectal surgery with spinal anesthesia on postoperative pain severity reduction.
- Conditions
- Hemorrhoids, Hemorrhoid Pain, Hemorrhoidal Bleeding
- Trial name
- NCT05772351
- Testing
- micronized flavonoid fraction
- Where
- Russia
- Volunteers
- 182 people
- Sponsor
- Center of Endourology "Endocenter"
Hemorrhoid Bleeding, Hemorrhoids Prolapse
Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal Disease
The goal of this observational study is to evaluate the effectiveness of topical nifedipine 0.3% plus lidocaine 1.5% for uncomplicated hemorrhoidal disease.
- Conditions
- Hemorrhoid Bleeding, Hemorrhoids Prolapse, Hemorrhoid Pain, Hemorrhoid
- Trial name
- NILOS (NCT07295886)
- Testing
- topical nifedipine 0.3% plus lidocaine 1.5%
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Cardarelli Hospital
Hemorrhoids, Surgery
Impact of Moderate to Severe Pain in the Post-intervention Monitoring Room After Hemorrhoidectomy on the Length of Stay in the Outpatient Surgery Unit
The target rate for outpatient surgery has been set by the Ministry of Health at 70% for 2020. To achieve this objective, this requires increasing the panel of eligible outpatient procedures to more mutilating surgeries and…
- Trial name
- HEM_DOULEUR (NCT04567485)
- Where
- France
- Volunteers
- 446 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Hemorrhoids
Irritation and Anal Bleeding in Patients Affected by Hemorrhoids.
Haemorrhoidal disease is an increasingly frequent benign condition, able to negatively affect the quality of working and relationship life in affected individuals.The primary objective of the study is the comparative assessment…
- Trial name
- IR-AN-BLEED (NCT03569930)
- Testing
- flavonoid-based supplements, Centella Complex, standard of care
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- University of Roma La Sapienza
Anus Diseases, Gastrointestinal Diseases
Evaluation of the Effectiveness of a Topical Medical Device in Wound Healing and Symptom Relief in the Postoperative Period of Open Excisional Hemorrhoidectomy (The Emor Study)
This multicenter randomized controlled phase IV trial aims to compare the clinical efficacy of a gel containing a Propionibacterium extract and a gel with hyaluronic acid and silver sulfadiazine in the degree of epithelialization…
- Conditions
- Anus Diseases, Gastrointestinal Diseases, Intestinal Diseases, Cicatrization
- Trial name
- NCT06872151
- Testing
- Gel containing a Propionibacterium extract, Hyaluronic acid and silver sulfadiazine
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- University of Cagliari
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Postoperative Pain
Postoperative Pain and Tenesmus After Doppler-Guided Hemorrhoidal Artery Ligation With or Without Mucopexy
Hemorrhoidal disease is one of the most common anorectal disorders affecting adults worldwide. Doppler-guided hemorrhoidal artery ligation (HAL) is a minimally invasive surgical technique that has gained popularity because of its…
- Trial name
- NCT07710053
- Testing
- HAL + Mucopexy, HAL Alone
- Volunteers
- 150 people
- Sponsor
- Ali Genc