Clinical trials: Hemorrhoids
Bleeding Hemorrhoids
A Prospective, Randomized, Three Arms, Open Label Study Comparing the Safety and Efficacy of Two Formulations of PP110 to the Active Comparator Preparation-H® Cream in the Treatment of Bleeding Hemorrhoids Grades 2-3
Eligible patients with bleeding hemorrhoids of grade 2-3 are randomized to test-1 product (PP110 Gel), test-2 product (PP-110 medicated wipes) or control (Preparation-H cream).
- Trial name
- NCT02010099
- Testing
- PP110 Gel, PP110 Medicated wipes, Preparation-H Cream
- Where
- 5 sites in Israel
- Volunteers
- 101 people
- Sponsor
- Peritech Pharma Ltd.
Hemorrhoid Pain, Haemorrhoid Inflammation
Efficacy and Safety of CONAN® Proctological Cream for Treatment of Haemorrhoidal Disease
Aim of the study is to assess the efficacy, safety and tolerability of CONAN® (Proctological Cream, Medical Device, Omikron Italia Srl) on most frequent symptoms in grade 1-2 of haemorrhoidal disease and anal fissures.
- Trial name
- NCT05984641
- Testing
- CONAN® Proctological Cream
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Omikron Italia S.r.l.
Haemorrhoids
Randomised, Double-blind, Placebo-controlled to Assess the Efficacy and Safety of the Food Supplement Microsmin® Plus
Haemorrhoids are variceal dilatations of the anal and perianal venous plexus and often develop secondary to the persistently elevated venous pressure within the haemorrhoidal plexus .
- Trial name
- NCT05750563
- Testing
- diosmin and micronized flavonoids
- Where
- Romania
- Volunteers
- 80 people
- Sponsor
- Giellepi S.p.A
Hemorrhoids
Efficacy Study of Iferanserin to Treat Hemorrhoids
To evaluate the safety and efficacy of topical 0.5% S-MPEC cream vs. placebo cream (applied twice daily for 14 days) in the treatment of Grade I - III hemorrhoids.
- Trial name
- NCT01483833
- Testing
- Iferanserin
- Where
- Germany
- Volunteers
- 121 people
- Sponsor
- Ventrus Biosciences, Inc
Hemorrhoid
Study of Pain Control in Hemorrhoidectomy
Patients will get an injection of either SKY0402 or placebo during hemorrhoid surgery, and their pain and pain medicine use will be monitored.
- Trial name
- NCT00890721
- Testing
- SKY0402
- Where
- Poland
- Volunteers
- 189 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Hemorrhoids
aCute HemORrhoidal Disease evALuation International Study
The primary objective of this study is to assess in real-life setting the effectiveness of conservative treatments on signs, symptoms and quality of life in patients consulting for hemorrhoids in acute phase of the disease
- Trial name
- CHORALIS (NCT04578730)
- Where
- France
- Volunteers
- 3,592 people
- Sponsor
- Servier Affaires Médicales
Hemorrhoids, Anal Fissures
Trial to Evaluate Effect of Lactulose on Hard Stools in Patients With Hemorrhoids or Anal Fissures
To demonstrate that lactulose acts as a stool softener, relieving the pain at defecation, improving the number of defecations and regulating the colonic transit time in patients suffering of hemorrhoids or anal fissure.
- Trial name
- NCT00160290
- Testing
- Lactulose, Plantago ovata
- Where
- 8 sites in Spain
- Volunteers
- 97 people
- Sponsor
- Solvay Pharmaceuticals
Hemorrhoids
Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids
A Randomized Phase 2 double blind study which aims to determine the safety and efficacy of CITI-002 cream in adult patients with Goligher's grade II or III hemorrhoids.
- Trial name
- NCT05348200
- Testing
- Monad 1, Monad 2, Monad 3
- Where
- 16 sites in United States
- Volunteers
- 304 people
- Sponsor
- Citius Pharmaceuticals, Inc.
Haemorrhoids
The Russian Multicenter Observational Study "Evaluation of the HDQ for the Diagnosis of Hemorrhoidal Disease ( HDQ )
Currently in Russia there is no available self-evaluating tools with appropriate diagnostic accuracy for screening of patients with haemorrhoids.
- Trial name
- HDQ (NCT04943666)
- Testing
- Hemorrhoid Disease Questionnaire
- Where
- Russia
- Volunteers
- 725 people
- Sponsor
- Servier Russia
Hemorrhoids
Prevention and/or Reduction of Hemorrhoids and/or Thrombosed External Hemorrhoids Using the HEM-AVERT Perianal Stabilizer Instrument
This study is being conducted to evaluate an investigational instrument called the HEM-AVERT Perianal Stabilizer and its efficacy in reducing the occurrence or severity of hemorrhoids and thrombosed external hemorrhoids (TEH)…
- Trial name
- HEM-AVERT (NCT00487045)
- Testing
- Hem-Avert Perianal Stabilizer
- Where
- 3 sites in United States
- Volunteers
- 176 people
- Sponsor
- Stetrix, Inc.
Arteriovenous Malformation, Gastrointestinal Bleed
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
The purpose of the Case-Specific Health Care Professional (HCP) Clinical Survey for Concerto Versa™ Detachable Coils, also known as the Concerto Versa HCP Clinical Assessment, is to collect early clinical data from HCPs to assess…
- Conditions
- Arteriovenous Malformation, Gastrointestinal Bleed, Gastric Varices, Hemorrhoid
- Trial name
- NCT07639853
- Testing
- Concerto Versa™ Detachable Coils
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medtronic Endovascular
Hemorrhoids
Effectiveness & Safety of Neofitoroid® in Hemorrhoidal Disease
Evaluation of the effect and safety of NeoFitoroid® in reducing symptoms in patients with hemorrhoidal disease.
- Trial name
- NCT03545724
- Testing
- Neofitoroid®
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aboca Spa Societa' Agricola
Hemorrhoid
Safety and Performance of the Covidien EEA Hemorrhoid and Prolapse Stapling Set in a Hemorrhoidopexy Procedure
Trial Objectives The primary objectives of this clinical trial are to estimate the Covidien EEA™ Hemorrhoid and Prolapse Stapling Set: overall performance defined by the successful creation of a normal staple line safety as…
- Trial name
- NCT01169311
- Testing
- Hemorrhoidopexy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Medtronic - MITG
Hemorrhoids
A Comparative Efficacy and Safety Study of Compound Carraghenates Cream With Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids
The purpose of this study is to compare the therapeutic effect and safety of compound carraghenates cream with Mayinglong musk hemorrhoid (swollen veins in the lower part of the rectum or anus) ointment in the treatment of…
- Trial name
- NCT01881282
- Testing
- Carraghenates Cream, Mayinglong Musk Hemorrhoid Ointment
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Hemorrhoids
To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids
The purpose of this study is to determine the safe and efficacious dose of Euphorbia prostrata for control of per rectal bleeding in patients with first and second degree hemorrhoids.
- Trial name
- NCT01041911
- Testing
- Euphorbia tablets
- Where
- 6 sites in India
- Volunteers
- 102 people
- Sponsor
- Panacea Biotec Ltd
Hemorrhoids, Hemorrhoids, Internal
SCI-Pex Study - Safety and Performance of PexyEazy®, a Device for Treatment of Hemorrhoids
The SCI-Pex study is a multicenter, prospective, non-controlled investigation on PexyEazy®, a new device for treatment of hemorrhoids based on the mucopexy method.
- Conditions
- Hemorrhoids, Hemorrhoids, Internal, Suture; Complications, Infection or Inflammation, Rectal Diseases
- Trial name
- SCI-Pex (NCT05782010)
- Testing
- PexyEazy
- Where
- 3 sites in Sweden
- Volunteers
- 35 people
- Sponsor
- Developeration AB
Hemorrhoid, Internal Hemorrhoids
Prospective HemorrhoIdaL EmboliSation (PILES) Registry
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults…
- Conditions
- Hemorrhoid, Internal Hemorrhoids, Hemorrhoid Bleeding, Hemorrhoidal Bleeding
- Trial name
- PILES (NCT07635784)
- Testing
- Hemorrhoid Artery Embolization
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Joint & Vascular Institute
Haemorrhoids
Evaluation of the Effectiveness of Micronized Purified Flavonoid Fraction (MPFF) in Patients With Haemorrhoids Undergoing Minimally Invasive Surgical Interventions
Evaluation of the effectiveness of micronized purified flavonoid fraction (MPFF) as part of the conservative therapy and impact on quality of life and satisfaction with treatment in the real-life clinical practice in patients…
- Trial name
- DEMAND HD (NCT07647172)
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Servier Russia
Hemorrhoids
Clinical Trial of Anusol Ointment for Symptom Relief in Patients With Haemorrhoids
The purpose of this study is to assess the efficacy and safety of Anusol topical ointment for the relief of internal and external haemorrhoid symptoms in people with Grades I-III haemorrhoids compared to a placebo (the study…
- Trial name
- NCT05157711
- Testing
- Anusol, Relief [Name]
- Where
- 2 sites in Armenia
- Volunteers
- 66 people
- Sponsor
- Church & Dwight Company, Inc.
Haemorrhoids Without Complication
Efficacy and Safety of Hemorrane Plus Versus Hemorrane and Versus Placebo in Patients With Uncomplicated Haemorrhoids
This is a Multicentre, double-blind, randomised clinical trial to evaluate and compare the efficacy and safety of Hemorrane Plus (Hemorrane® + benzocaine) with Hemorrane® and with placebo in patients with uncomplicated…
- Trial name
- NCT05788497
- Testing
- Hemorrane plus, Hemorrane
- Where
- 13 sites in Spain
- Volunteers
- 21 people
- Sponsor
- Faes Farma, S.A.