Clinical trials: Hemorrhoids Third Degree
Hemorrhoids Prolapse
Doppler-guided or Non Doppler-guided Arterial Ligation and Mucopexy for Third Degree Hemorrhoids: That is the Question
Hemorrhoidal disease is one of the most common proctological disease affecting the general population from the mid-teens onward with considerable implications for the National Health Service (NHS) both from an economic point of…
- Trial name
- HAMLeT (NCT03729414)
- Testing
- mucopexy with Doppler artery ligation, mucopexy without Doppler artery ligation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Hemorrhoids
Prospective Randomized Trial Comparing THD Versus Stapler Operation for 3rd Degree Hemorrhoids
Haemorrhoids have, in literature, extremely high ranges of prevalence, 4,4% to 36% and there is a debate on the best treatment for III degree hemorrhoids.
- Trial name
- THD/stapler (NCT00823784)
- Testing
- Transanal doppler hemorrhoidal ligation, stapled hemorrhoidopexy
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Hemorrhoidectomy, Third Degree Hemorrhoids
Hemorrhoidectomy in Patients With Grade III and IV Disease:Harmonic Scalpel Compared With Conventional Technique
Hemorrhoidectomy is the treatment of choice for grade 3 and 4th degree hemorrhoids. Various surgical technique has been used to improve the outcome of the procedures performed in respect to operative time ,post operative pain and…
- Conditions
- Hemorrhoidectomy, Third Degree Hemorrhoids, Fourth Degree Hemorrhoids, Operative Time
- Trial name
- NCT03938714
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Postoperative Pain, Hemorrhoids Third Degree
Efficacy of Ice Packing Application in Post-Hemorrhoidectomy Recovery
According to the previous study, surgical intervention exhibited significant differences in daily life before and after a hemorrhoidectomy.
- Conditions
- Postoperative Pain, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids
- Trial name
- ICE-HEMO (NCT07186348)
- Testing
- Ice packing, Standard Care (in control arm)
- Where
- Taiwan
- Volunteers
- 429 people
- Sponsor
- Chang Gung Memorial Hospital
Third Degree Hemorrhoids
Comparison Between Excisional Hemorrhoidectomy and Haemorrhoidal Dearterialisation With Anopexy
Aim of the study is to compare short term results of 2 surgical treatment for grade 3 hemorrhoidal disease, namely: pain and postoperative morbidity,complications and effectiveness within 30 days, re-starting daily and working…
- Trial name
- NCT01263431
- Testing
- Hemorrhoidectomy, Hemorrhoidal dearterialization
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Scientific Institute San Raffaele
Hemorrhoids Third Degree, Internal Hemorrhoids
HELO Trial: Energy-Based Therapies vs. Conventional Hemorrhoidectomy for Grade III Hemorrhoids
This prospective, multicenter study compares the efficacy and functional outcomes of three surgical treatments for symptomatic Goligher Grade III internal hemorrhoids: Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy…
- Conditions
- Hemorrhoids Third Degree, Internal Hemorrhoids, Mixed Hemorrhoids
- Trial name
- HELO (NCT07333040)
- Testing
- Laser Hemorrhoidoplasty (LHP), Hemorrhoid Energy Therapy (HET), Ferguson Hemorrhoidectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Randomized Trial :Hemorrhoidal Pedicle Ligation vs Laser vs Open Hemorrhoidectomy
The aim of this study is to compare three different modalities for treatment of symptomatic 2 ° to 3 ° haemorrhoids: open haemorrhoidectomy, intrahaemorrhoidal laser procedure and haemorrhoidal pedicle ligation.
- Trial name
- NCT03757728
- Testing
- Haemorrhoidectomy operations
- Where
- Lithuania
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Third Degree Hemorrhoids
Doppler-guided Haemorrhoidal Artery Ligation With Suture Mucopexy vs. Suture Mucopexy Alone
Novel minimally invasive techniques were established for prolapsing haemorrhoids to minimise the drawbacks of the golden standard of haemorrhoidal treatment, conventional haemorrhoidectomy techniques.
- Trial name
- NCT02372981
- Testing
- mucopexy +/- Doppler-guided haemorrhoidal artery ligation
- Volunteers
- 40 people
- Sponsor
- Medical University Innsbruck
Hemorrhoidectomy, Hemorrhoids Third Degree
Comparison Study: Ligasure Versus Conventional Hemorrhoidectomy in III and IV Degree Hemorrhoids.
A comparison study was performed between Ligasure and Milligan morgan hemorrhoidectomy to find out the outcome between these two techniques in 3rd and 4th degree hemorrhoids.This advance vessel sealing device is used to seal the…
- Conditions
- Hemorrhoidectomy, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Operative Time
- Trial name
- NCT03848468
- Testing
- Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Hemorrhoids
Laser Hemorrhoidoplasty Versus Open Surgical Hemorrhoidectomy in Second and Third Degree Piles
The study aims to compare the pain , duration of intervention and long term outcomes of laser hemorrhoidoplasty versus open surgical hemorrhoidectomy
- Trial name
- NCT05770141
- Testing
- laser hemorrhoidoplasty, open surgical hemorrhoidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain.
- Conditions
- Hemorrhoids Second Degree, Hemorrhoids Third Degree, Internal Hemorrhoids
- Trial name
- LHP-MMH (NCT07678814)
- Testing
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allama Iqbal Medical College
Anus Diseases, Gastrointestinal Diseases
Evaluation of the Effectiveness of a Topical Medical Device in Wound Healing and Symptom Relief in the Postoperative Period of Open Excisional Hemorrhoidectomy (The Emor Study)
This multicenter randomized controlled phase IV trial aims to compare the clinical efficacy of a gel containing a Propionibacterium extract and a gel with hyaluronic acid and silver sulfadiazine in the degree of epithelialization…
- Conditions
- Anus Diseases, Gastrointestinal Diseases, Intestinal Diseases, Cicatrization
- Trial name
- NCT06872151
- Testing
- Gel containing a Propionibacterium extract, Hyaluronic acid and silver sulfadiazine
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- University of Cagliari
Hemorrhoids Third Degree
Open Hemorrohoidectomy Vs Transanal Hemorrhoidal Desarterialization in Hemorrhoids Grade III: The Effect on Symptoms
The goal of this clinical trial is to learn if open hemorroidectomy diminishes symptoms compared to transanal hemorrhoidal desarterialization (THD) in patients presenting with hemorrhoids grade III.
- Trial name
- NCT06420986
- Testing
- Open Hemorrhoidectomy, Transanal Hemorrhoidal Dearterialization
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Son Llatzer
Pain Management, Hemorrhoids Third Degree
Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a topical ointment containing two local anesthetics (lidocaine 23% and tetracaine 7%) can reduce pain after hemorrhoid surgery in adults.
- Conditions
- Pain Management, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids Second Degree
- Trial name
- NCT07688031
- Testing
- Lidocaine 23% / Tetracaine 7% topical ointment (compounded)
- Where
- Chile
- Volunteers
- 74 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Hemorrhoids
Trans-anal Hemorrhoidal Dearterialization (THD) vs. Hemorrhoidectomy
The purpose of this study is to compare the frequency and severity of postoperative( after surgery) pain between two surgical techniques for treating severe hemorrhoids.
- Trial name
- THD (NCT01244672)
- Testing
- Ferguson, THD
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
Hemorrhoidectomy, Hemorrhoids Third Degree
Minimally Invasive Open Excisional Hemorrhoidectomy Compared to Conventional Open Excisional Hemorrhoidectomy: a Clinical Trial
This study aims to demonstrate that open excisional hemorrhoidectomy (OEH), when performed using a minimally invasive approach, results in less postoperative pain and comparable outcomes to conventional OEH.
- Conditions
- Hemorrhoidectomy, Hemorrhoids Third Degree, Hemorrhoidal Disease, Postoperative Pain
- Trial name
- NCT06764849
- Testing
- CONVENTIONAL OPEN EXCISIONAL HEMORRHOIDECTOMY, MINIMALLY INVASIVE OPEN EXCISIONAL HEMORRHOIDECTOMY
- Sponsor
- Hospital Son Llatzer
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Hemorrhoids, Hemorrhoids Third Degree
PUSHES (Pudendal Block Versus Sacral ESP Hemorrhoidectomy Study)
The goal of this clinical trial is to learn if the sacral erector spinae plane block can provide equal or better pain control than the pudendal nerve block in adults undergoing hemorrhoid surgery.
- Trial name
- PUSHES (NCT07350460)
- Testing
- Pudendal block AL, Sacral ESP block AL
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Andrea Saporito