Clinical trials: Heparin
Heparin-induced Thrombocytopenia (HIT)
Rapid Diagnosis of Heparin-Induced Thrombocytopenia in Surgical Critically Ill Patients
The early diagnosis of heparin-induced thrombocytopenia is particularly difficult in surgical critically ill patients. If the use of rapid immunological diagnostic methods and pretest scoring systems has been proposed in the…
- Trial name
- TIH (NCT02790567)
- Testing
- HEP score, 4Ts score, ID-PaGIA test
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Heparin-induced Thrombocytopenia
Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced Thrombocytopenia
Heparin is an anticoagulant (blood thinner) that is commonly used to treat patients with heart attacks and patients with blood clots in their legs or lungs (venous thrombosis).
- Trial name
- NCT01598168
- Testing
- Rivaroxaban
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- McMaster University
Heparin Induced Thrombocytopenia
Heparin-Induced Thrombocytopenia - Retrospective Analysis of Data on Incidence and Outcomes Study
HIT-RADIO is a study of patients who had a positive heparin PF-4 antibody test between 1/21/2008 and 9/25/2008 at selected hospitals.
- Trial name
- HIT-RADIO (NCT01178333)
- Where
- 21 sites in United States
- Volunteers
- 668 people
- Sponsor
- Carelon Research
Thrombosis, Heparin-induced Thrombocytopenia
Pilot Dose Finding and Pharmacokinetic Study of Fondaparinux in Children With Thrombosis
This study will evaluate the use of a blood thinner, fondaparinux, which is approved for use in adults (not in children) in a children aged 1-18 years.
- Trial name
- NCT00412464
- Testing
- Fondaparinux
- Where
- 4 sites in United States
- Volunteers
- 24 people
- Sponsor
- Children's Hospital Los Angeles
Heparin-Induced Thrombocytopenia
Heparin-Induced Thrombocytopenia Score Card Study
Main Research Question: Can two new types of test, one called the 4T's score and the other called a rapid assay, help doctors correctly identify which patients are unlikely to have heparin-induced thrombocytopenia (HIT)? HIT is a…
- Trial name
- NCT00489437
- Testing
- ID-PaGIA Heparin/PF4 antibody test, Clinical Prediction Score-HIT Score Card
- Where
- Canada
- Volunteers
- 536 people
- Sponsor
- McMaster University
To Investigate the Effects of Low Dose Aspirin and Low Molecular Weight Heparin in IVF Out Come
Effects of Aspirin and Low Molecular Weight Heparin in IVF Outcome.
The purpose of the study is to determine whether low-dose aspirin and low molecular weight heparin improve the implantation and pregnancy rates in patients with repeated implantation failures in IVF cycle.
- Trial name
- NCT01924104
- Testing
- Low molecular weight heparin, Low dose aspirin, Heparin & aspirin
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Dr.Vandana Bansal
Suspected Heparin-Induced Thrombocytopenia
A Comparative Sudy Comparing Argatroban® IV vs Desirudin SC for Suspected HIT With or Without Thrombosis Syndrome
Compare Clinical Success and Costs in two Arms
- Trial name
- HIT (NCT00787332)
- Testing
- Desirudin or Argatroban®
- Where
- 24 sites in United States
- Volunteers
- 16 people
- Sponsor
- Canyon Pharmaceuticals, Inc.
Heparin
The Effect of Heparin on Inhalation Injury
This is a prospective randomized clinical trial about the efficacy of heparin nebulization on lung injury score in inhalation burn injury in Mothary burn hospital.
- Trial name
- NCT01454869
- Testing
- standard care, Heparin
- Where
- Iran
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Heparin-induced Thrombocytopenia
Heparin-Induced Thrombocytopenia: Development and Validation of a Predictive Clinical
Although Heparin-induced thrombocytopenia (HIT) is a rare complication of heparin treatment, it results in a high rate of morbidity and mortality, the cumulative rate of thrombosis recurrence, amputation and death approaching 52…
- Trial name
- Score-TIH (NCT00748839)
- Where
- 27 sites in France
- Volunteers
- 2,700 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Heparin-induced Thrombocytopenia, Liver Transplantation
Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients
In a prospective observational study the incidence of Heparin-induced Thrombocytopenia (HIT) Type 2 after orthotopic liver transplantation, associated factors, and hemostaseological findings in thrombocytes and anti-body patterns…
- Trial name
- HITOLT (NCT01654848)
- Where
- Germany
- Volunteers
- 39 people
- Sponsor
- CHIR-Net
Heparin Induced Thrombocytopenia (HIT)
Argatroban Versus Lepirudin in Critically Ill Patients
The purpose of this study is to test the hypotheses that argatroban significantly increases efficacy and safety of renal replacement therapy measured as life time of haemodialysis filters as compared to lepirudin
- Trial name
- ALiCia (NCT00798525)
- Testing
- Argatroban, Lepirudin
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
The Primary Study Objective is to Assess the Efficacy and, Safety of Extended 4-week Heparin Prophylaxis Compared to
ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER.
Overall, only limited evidence exists regarding the clinical benefit of antithrombotic prophylaxis after laparoscopic surgery for cancer.
- Conditions
- The Primary Study Objective is to Assess the Efficacy and, Safety of Extended 4-week Heparin Prophylaxis Compared to, Prophylaxis Given for 8±2 Days After Planned Laparoscopic, Surgery for Colorectal Cancer.
- Trial name
- PRO-LAPS I (NCT01589146)
- Testing
- Heparin, Low-Molecular-Weight
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Of Perugia
Heparin-Induced Thrombocytopenia, Thrombosis
Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)
Primary Objective: To assess the safety of bivalirudin as an alternative anticoagulant therapy for patients with new or previous heparin-induced thrombocytopenia (HIT) / heparin-induced thrombocytopenia and thrombosis syndrome…
- Trial name
- NCT00043940
- Testing
- bivalirudin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Medicines Company
Heparin-Induced Thrombocytopenia, Thrombosis
Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure
The purpose of this study is to determine the HIT-antibody generation without prior heparin-exposure in patients undergoing orthopedic surgery.
- Trial name
- NCT01102790
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Heparin-Induced Thrombocytopenia
Validating 4Ts for Heparin Induced Thrombocytopenia (HIT)
The purpose of this study is to evaluate a scoring tool to help determine the presence of Heparin Induced Thrombocytopenia (HIT), which is an adverse reaction to heparin.
- Trial name
- NCT00946400
- Testing
- Scoring 4Ts and Chong scale, Blood draw
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Medstar Health Research Institute
Contra-Indication to the Use of Low Molecular Weight Heparin
Chronic Hemodialysis Without Systemic Heparinization : a Randomized Study
Conventional hemodialysis requires transient systemic anticoagulation to prevent blot clotting after contact with the extracorporeal circuit.
- Trial name
- HDSH (NCT00473109)
- Testing
- Dialysis without systemic heparinization
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heparin Induced Thrombocytopenia (HIT)
Heparin Induced Thrombocytopenia: Pharmacoeconomics
Patients at BWH receiving unfractionated heparin or enoxaparin who subsequently develop heparin induced thrombocytopenia will be identified via a computer generated report designed for the purposes of this study.
- Trial name
- NCT00456001
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Brigham and Women's Hospital
Heparin-Induced Thrombocytopenia
Efficacy and Safety Study of Argatroban to Treat Heparin-Induced Thrombocytopenia
The purpose of the study is to evaluate efficacy and safety of argatroban in the patients with heparin-induced thrombocytopenia (HIT)/ HIT and thrombosis syndrome (HITTS).
- Trial name
- NCT00198588
- Testing
- argatroban
- Where
- 20 sites in Japan
- Volunteers
- 8 people
- Sponsor
- Ministry of Health, Labour and Welfare, Japan
Heparin-Induced Thrombocytopenia
Heparin-Induced Thrombocytopenia Registry
The purpose of the Heparin Induced Thrombocytopenia Registry is to explore the frequency of heparin-induced thrombocytopenia (HIT) at Brigham and Women's Hospital and to assess its mortality rate.
- Trial name
- HIT (NCT00456326)
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Brigham and Women's Hospital
Heparin-Induced Thrombocytopenia
Heparin Antibodies in Intensive Care Unit Patients (HAICU)
Intensive care unit patients have multiple risk factors for venous thromboembolism. Venous thromboembolism leads to significant morbidity and can be fatal.
- Trial name
- NCT00283322
- Testing
- blood samples (2)
- Where
- 2 sites in United States
- Volunteers
- 185 people
- Sponsor
- The University of Texas Health Science Center, Houston