Clinical trials: Hernia, Abdominal
Fetal Surgery, Myelomeningocele
Fetal Surgery Interview Study: Parental Perceptions of Fetal Surgery
Open maternal-fetal surgery is currently used on fetuses with myelomeningocele (MMC). Fetoscopic or minimal access fetal surgery is also being used to treat fetuses with congenital diaphragmatic hernia (CDH).
- Conditions
- Fetal Surgery, Myelomeningocele, Congenital Diaphragmatic Hernia
- Trial name
- NCT03788122
- Testing
- In-depth interview
- Where
- 2 sites in Belgium, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ventral Hernia, Umbilical Hernia
Preperitoneal Umbilical Mesh Area
The aim of this study is to measure the mesh shrinkage and the visualization of the mesh with MRI scan at 1 month and 13 months after robot assisted preperitoneal hernia repair using the visible CICAT mesh (Dynamesh®).
- Conditions
- Ventral Hernia, Umbilical Hernia, Ventral Incisional Hernia
- Trial name
- PUMA (NCT05576753)
- Testing
- Hernia repair
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Inguinal Hernia
Ultrasound-guided Inguinal Field Block (Genitofemoral, Iliohypogastric and Ilioinguinal Nerve Block) for Inguinal Hernia Surgery
The purpose of this study is to investigate the analgesic efficacy of an ultrasound-guided inguinal field block (block of the genitofemoral, iliohypogastric and ilioinguinal nerve).
- Trial name
- U-IFB (NCT01521481)
- Testing
- Triple inguinal nerve block., Unilateral subarachnoid anesthesia
- Where
- Italy
- Volunteers
- 87 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Liver Cirrhosis, Hernia
Abdominal Hernia in Cirrhotic Patients: Surgery or Conservative Treatment?
Cirrhotic patients have a high incidence of abdominal wall hernias. Ascites and sarcopenia are risk factors to development of bigger hernias and frequent need for urgent surgery due parietal complications.
- Conditions
- Liver Cirrhosis, Hernia, Ascites, Surgery
- Trial name
- NCT02787772
- Testing
- Elective Hernia repair
- Volunteers
- 246 people
- Sponsor
- University of Sao Paulo General Hospital
Congenital Diaphragmatic Hernia
Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia
This study aims to measure the cardio-respiratory physiological consequences of initiating resuscitation during placental transfusion (PT) with an intact umbilical cord in infants with congenital diaphragmatic hernia (CDH).
- Trial name
- INSPIRE-CDH (NCT03094039)
- Testing
- Ventilatory support while attached to the cord, Immediate cord clamping
- Where
- Canada
- Sponsor
- University of Alberta
Ventral Hernia, Abdominal Wall Defect
Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Background: A detailed study of the biomechanical changes before and after abdominal wall reconstruction (AWR) has not been performed.
- Trial name
- NCT03296475
- Testing
- Abdominal Wall Closure Force (N).
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Gastroschisis, Anorectal Malformation
Children's Surgery in Sub-Saharan Africa
Background: Five billion people worldwide do not have access to safe, affordable surgical care. A significant proportion live in sub-Saharan Africa (SSA), where up to 50% of the population are children.
- Conditions
- Gastroschisis, Anorectal Malformation, Appendicitis, Intussusception
- Trial name
- PaedSurgAfrica (NCT03185637)
- Testing
- Various interventions for each of the conditions.
- Where
- United Kingdom
- Volunteers
- 1,407 people
- Sponsor
- King's College London
Incisional Hernia
The Effect of Postoperative Abdominal Binder to Improve Outcomes After Incisional Hernia Repair
Postoperative seroma formation is one of the most common complications after ventral hernia repair with mesh. Although some seromas may not have clinical impact postoperative seroma formation often causes pain and discomfort and…
- Trial name
- INSAB (NCT01776775)
- Testing
- Abdominal binder
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Hernia, Inguinal
The Desarda and Lichtenstein Techniques in Inguinal Hernia Treatment.
Contemporary treatment of inguinal hernia is generally based on surgical methods with the use of synthetic meshes. The implanted meshes however have some disadvantages: they increase the risk of infection, tend to sustain…
- Trial name
- DESLICH (NCT01237470)
- Testing
- Desarda technique, Lichtenstein technique
- Where
- Poland
- Volunteers
- 2,009 people
- Sponsor
- Nicolaus Copernicus University
Congenital Diaphragmatic Hernia
Fetal Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia
The purpose of the study is to study the efficacy of fetal endoscopic tracheal occlusion (FETO) in cases of severe congenital diaphragmatic hernia (CDH).
- Trial name
- FETO (NCT05461222)
- Testing
- Balt "Goldballoon"
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yair Blumenfeld
Gastroschisis, Intestinal Ischemia
Regional Blood Saturation Levels in Gastroschisis
Gastroschisis is one of the most common neonatal surgical conditions, and is increasing in incidence. Postnatal bowel ischemia leading to necrosis, bowel loss and short-bowel syndrome, occurs in a few instances, with significant…
- Trial name
- NCT03533439
- Testing
- Near infrared spectroscopy
- Volunteers
- 19 people
- Sponsor
- NHS Lothian
Hernia, Inguinal, Postoperative Pain
Comparison of Hernia Sac Ligation Versus Invagination
Management of indirect hernial sac in inguinal hernia repairs has long been a subject of debate among general surgeons. Although hernial sac high ligation (HL) is a time-honored concept in groin hernia surgery…
- Conditions
- Hernia, Inguinal, Postoperative Pain, Recurrence
- Trial name
- NCT05308251
- Testing
- Lichtenstein Mesh Hernioplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Samsun Education and Research Hospital
Inguinal Hernia, Circumcision
Analgesia in Children Using Caudal Epidural Ropivacaine
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al…
- Trial name
- NCT01494272
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Inguinal Hernias
Polypropylene Meshes in Hernia Repair
The aim of this study was to analyze the shrinkage of two different screens in the repair of inguinal hernias in men . 32 patients with unilateral inguinal hernia were assigned randomly.
- Trial name
- NCT01090219
- Testing
- two different meshes in the repair of inguinal hernias
- Where
- 2 sites in Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Hernia of Abdominal Wall, Biologic Implant
The Permacol Dutch Cohort Study
Incisional hernia is the most frequently seen long term complication in surgery causing much morbidity and even mortality in patients.
- Conditions
- Hernia of Abdominal Wall, Biologic Implant, Infected Hernioplasty Mesh
- Trial name
- NCT02166112
- Testing
- Permacol mesh placement
- Where
- 24 sites in Netherlands
- Volunteers
- 77 people
- Sponsor
- Erasmus Medical Center
Inguinal Hernia
Neo-nervegenesis in Inguinal Hernia Implant ProFlor
The investigation is aimed at specifically demonstrating the ingrowth of newly formed nervous elements within a 3D dynamic responsive implant for inguinal hernia repair.
- Trial name
- NCT04171102
- Testing
- ProFlor Hernia implant
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Inguinal Hernia
Mesh Fixation inTEP Inguinal Hernia Repair
Mesh fixation is used to prevent recurrence in TEP to the potential cost of pain. The aim was to evaluate the impact of permanent fixation (PF) versus non-permanent fixation (N-PF) of mesh in TEP repair for a primary inguinal…
- Trial name
- register (NCT02419950)
- Testing
- Fixation of mesh in TEP
- Where
- Sweden
- Volunteers
- 1,110 people
- Sponsor
- Skane University Hospital
Groin Hernia
Case Report in Complications After Laparoscopic Transabdominal Preperitoneal Groin Hernia Repair Using LiquiBandFIX8®
This an a case report about management and proving the strenght and resistance of LiquiBandFIX8® using for peritoneal closure in a laparoscopic transabdominal preperitoneal groin hernia repair.
- Trial name
- NCT05952791
- Testing
- Surgery
- Where
- Austria
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kepler University Hospital