Clinical trials: Hernia, Incisional
Incisional Hernia
Incisional heRnia dIgestion Sexuality
After an operation on the abdomen, some patients present with an incisional hernia(incisional hernia) which causes a permanent exteriorization of the vicera. This situation is at the origin of postural problems.
- Trial name
- IRIS (NCT05596357)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Open Midline Laparotomy
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
This trial is being conducted to evaluate the efficacy of Phasix™ Mesh implantation at the time of midline fascial closure compared to primary suture closure in preventing a subsequent incisional hernia in subjects at risk for…
- Trial name
- PREVENT (NCT03911700)
- Testing
- Phasix™ Mesh
- Where
- 32 sites in United States, Austria and 3 more
- Volunteers
- 477 people
- Sponsor
- C. R. Bard
Chronic Pain, Wound Dehiscence
Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure
This randomized controlled trial aims to compare the outcomes of Polyglactin (Vicryl) versus Polypropylene (Prolene) sutures for rectus sheath closure in patients undergoing midline laparotomy.
- Conditions
- Chronic Pain, Wound Dehiscence, Surgical Site Infection (SSI), Incisional Hernia
- Trial name
- PolySuture (NCT07280975)
- Testing
- Polyglactin 910 (Vicryl) Suture, Polypropylene (Prolene) Suture
- Where
- Pakistan
- Volunteers
- 156 people
- Sponsor
- Lady Reading Hospital, Pakistan
Incisional Hernia, Umbilical Hernia
Laparoscopic or Conventional Mesh Repair of Incisional and Umbilical Hernia
The aim of this study is to compare immediate and long-term (24 months) results of laparoscopic and open mesh repair of incisional and umbilical hernia.
- Trial name
- EVENTRALAP (NCT00970515)
- Testing
- Laparoscopic mesh hernia repair, Open anterior approach
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hernia, Ventral
The Use of Local Hemostatic in Patients With Large Incisional Hernias
Design of a simple blind randomized controlled trial study. Large incisional hernia repair with use of local hemostatic Hemoblock
- Trial name
- NCT04222517
- Testing
- Incisional hernia repair by the mesh implant in sublay retromusuclar position, Incisional hernia repair by the mesh implant in sublay retromusuclar position with using a local hemostatic Hemoblock
- Where
- Russia
- Volunteers
- 66 people
- Sponsor
- Nijznevartovsk County Clinical Hospital
Ventral Incisional Hernia, Abdominal Wall Hernia
Robotic Versus Open Comparison in the Surgical Treatment of Wide Abdominal Wall heRnias (ROCSTAR)
In the treatment of ventral incisional hernias, a mesh repair in the retromuscular plane is considered as the gold standard. To allow for adequate medialization of the fascial borders and a complete closure of the defect in case…
- Trial name
- ROCSTAR (NCT05575141)
- Testing
- incisional hernia repair
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Ventral Hernia
Prevena Incision Management System Wound Care
Comparison of ventral hernia repair using standard wound care versus Prevena.
- Trial name
- NCT02953769
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- AdventHealth
Ventral Incisional Hernia
Quality Control of Ventral Hernia Surgery by Prospective Registration
Quality Control of ventral hernia surgery in 21 Belgian hospitals by prospective registration in close collaboration with the Danish Hernia Database.
- Trial name
- NCT04624100
- Testing
- Hernia repair
- Volunteers
- 5,000 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Incisional Hernia, Pelvic Cancer
Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer
The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual…
- Trial name
- VRAM (NCT00647569)
- Testing
- Mesh repair, Conventional facial closure
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Incisional Hernia of Midline of Abdomen
Barbed Suture for Emergency Midline Laparotomy Closure
Urgency surgeries are often performed in a stressful setting with critical patient involved. In this context, laparotomy closure can sometimes be the most neglected part of the procedure.
- Trial name
- BAROTOMY (NCT05351970)
- Testing
- Barbed
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Incisional Hernia, Obesity
Randomized Controlled Prospective Multicenter Study Primary Onlay- Mesh After Elective Median Laparotomy in Patients With BMI ≥ 27
Incisional hernia is one ot the most frequently seen long term complications in abdominal surgery. Despite studies on the optimal suturing technique for laparotomies, the risk for incisional hernia after midline incision remains…
- Trial name
- NCT01507870
- Testing
- onlay mesh placement
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Austrian Hernia Study Group
Hernia Abdominal Wall, Botox Injection
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the…
- Conditions
- Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome
- Trial name
- PRETOX (NCT07220382)
- Testing
- OnabotulinumtoxinA Injection, OnabotulinumtoxinA, 0.9 % Normal Saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Cleveland Clinic
Lumbar Hernia
On-lay Versus Pre-peritoneal Hernioplasty in Incisional Lumbar Hernia
To compare between the outcome of on-lay and pre-peritoneal techniques of hernioplasty in incisional lumbar hernia repair.
- Trial name
- NCT06757998
- Testing
- Mesh
- Volunteers
- 30 people
- Sponsor
- Assiut University
Ventral Incisional Hernia
SUTURE TYPE AND RECURRENCE RISK AFTER INCISIONAL HERNIA REPAIR
Incisional hernia is a common condition after abdominal surgery and is often associated with pain, impaired physical function, and reduced quality of life.
- Trial name
- TAFAR (NCT07891091)
- Testing
- Suturing of hernia defect with non-absorbable suture, Suturing of hernia defect with slowly absorbable suture
- Where
- Sweden
- Volunteers
- 980 people
- Sponsor
- Ersta Diakoni
Gallstone
TSH Risk by Extraction Site in Lap Cholecystectomy
The main purpose of this study is to determine whether removing the gallbladder through different incision sites (ports) during laparoscopic surgery affects the risk of developing an incisional hernia.
- Trial name
- NCT06953713
- Testing
- gallbladder extraction umbilical, extracting gallbladder via epigastric port
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Fatih Basak
Ventral Hernia
Biological Meshes in Infected Fields: a Randomized Controlled Trial
The SIMBIOSE trial is a large multicenter phase III prospective randomized controlled single blinded trial comparing the use of biological mesh versus traditional wound care without biological mesh in patients with an infected…
- Trial name
- SIMBIOSE (NCT01594450)
- Testing
- Biological mesh, without biological mesh
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Lille
Incisional Hernia
PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM)
To evaluate the efficacy of the use of swine dermal collagen prosthesis implanted preperitoneally as a prophylactic procedure against incisional hernia in patients operated in urgency/emergency setting in contaminated/infected…
- Trial name
- PROPHYBIOM (NCT02277262)
- Testing
- Biological swine dermis not cross-linked prosthesis positioning in incisional hernia prevention, Direct suture of the anterior abdominal wall fascia
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Ventral Hernia, Incisional Hernia
Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair
The goal of this clinical trial is to learn if cryoneurolysis, a targeted cold therapy applied to nerve branches, can relax the muscles of the abdomen to facilitate surgical repair of abdominal wall hernias.
- Conditions
- Ventral Hernia, Incisional Hernia, Hernia, Hernia Abdominal Wall
- Trial name
- NCT07874724
- Testing
- Cryoneurolysis
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of South Florida
Incisional Hernia
Validation of the Goodstrength System for Assessment of Abdominal Wall Strength in Patients With Incisional Hernia
Patients with an incisional hernia in the midline and controls with an intact abdominal wall are examined twice with one week apart, in order to establish the test-retest reliability and internal and external validity of the…
- Trial name
- VAGSI (NCT02321059)
- Testing
- Measurement of abdominal wall strength
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital