Clinical trials: Hernia, Incisional
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Ventral Hernia, Incisional Hernia
A Prospective Study of Fortiva in Hernia Repair
The goal of this study is to evaluate safety and performance of the Fortiva Tissue Matrix. Participants will complete questionnaires to measure outcomes after hernia surgery for two years.
- Conditions
- Ventral Hernia, Incisional Hernia, Abdominal Wall Reconstruction
- Trial name
- NCT06101979
- Testing
- Fortiva Tissue Matrix
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- RTI Surgical
Recurrent Hernia
Review of Complex Recurrent Hernia Repair
Abdominal wall incisional hernia is a common finding in patients who have undergone previous intra-abdominal surgeries. Common methods of abdominal fascial closure include primary closure, mesh inlay versus onlay, with or without…
- Trial name
- BARS (NCT01644695)
- Testing
- Bony Anchoring Reinforcement System
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Institute For Advanced Reconstruction
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Morbid Obesity, Weight Loss
Endoscopic Gastric Plication for Weight Loss in Morbidly Obese Patients Prior to Incisional Hernia Repair
Incisional hernias occur in nearly 20% of all laparotomy incisions accounting for almost 400,000 ventral hernia repairs annually in the United States.
- Conditions
- Morbid Obesity, Weight Loss, Complex Incisional Hernias
- Trial name
- NCT02078934
- Testing
- Endoscopic Gastric Plication
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Incisional Hernia
ACute Treatment of Incisional Ventral Hernia
This observational, retrospective study aims to examine surgical outcomes in non-elective surgery for incisional hernia. The main questions it aims to answer are: 30-day morbidity short- and long-term surgical outcomes Data will…
- Trial name
- ACTIVE (NCT05620121)
- Testing
- Surgery for Incisional hernias
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ospedale San Camillo
Umbilical Hernia
Cosmetic Outcomes of Umbilical Hernia Incisions
This will be a single institution, prospective, randomized controlled trial. Patients presenting as an outpatient for repair of umbilical hernias who meet our inclusion criteria, whose parents provide permission to participate in…
- Trial name
- UHR (NCT06738121)
- Testing
- Infra-umbilical incision, Transumbilical incision
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Children's Mercy Hospital Kansas City
Incisional Hernia
Efficacy of an Onlay Mesh for Prevention of Incisional Hernia After Loop Ileostomy Closure
The aim of the present study is to determine the efficacy of the placement of an onlay mesh to prevent incisional hernia after loop ileostomy closure in patients with a prior rectal resection for cancer
- Trial name
- ILEOMESH (NCT02896686)
- Testing
- Control CT, Clinical Follow Up, Reinforcement with Light Polypropylene Mesh
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Joan XXIII de Tarragona.
Incisional Hernia, Aortic Aneurysm
Prophylactic Mesh Reinforcement After Open Aortic Aneurysm Repair
The goal of this retrospective observational study is to evaluate whether prophylactic mesh reinforcement during abdominal wall closure can prevent incisional hernias (IH) in patients undergoing open abdominal aortic aneurysm…
- Trial name
- NCT06762561
- Testing
- Prophylactic retromuscular mesh reinforcement
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Surgery--Complications
The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation
STUDY SUMMARY Incisional hernias, or swellings of the abdominal scar after surgery, remain problematic especially after transplant surgery.
- Trial name
- NCT03959904
- Testing
- Small stitch, Blood sample, Tissue Sample
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Incisional Hernia Repair
Comparative Study of AESCULAP Optilene® Mesh Elastic Versus Ethicon Ultrapro® Mesh in Incisional Hernia Repair
Optilene® Mesh Elastic and Ultrapro® Mesh will be used for incisional hernia repair. The primary objective of this clinical study is to demonstrate that Optilene® Mesh Elastic is superior to Ultrapro® Mesh in incisional hernia…
- Trial name
- Optilene (NCT00646334)
- Testing
- Mesh Implantation
- Where
- 6 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Aesculap AG
Peritonitis, Incisional Hernia
Prophylactic Mesh Implantation in Patients With Peritonitis for the Prevention of Incisional Hernia
In patients undergoing laparotomy, the incidence of abdominal wall related complications such as incisional hernia is very high.
- Conditions
- Peritonitis, Incisional Hernia, Surgery
- Trial name
- PerProMe (NCT01802164)
- Testing
- A non-absorbable composite mesh (Ethicon Physiomesh)
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Incisional Hernia
XGBoost for Predict Incisional Hernia
The objective of this study is to develop a predictive model of IH based on machine learning with the use of the XGBoost technique, this will help surgeons in charge of abdominal wall closure to have objective support to…
- Trial name
- XGB&IncHern (NCT05718999)
- Testing
- Not intervention
- Where
- Mexico
- Volunteers
- 1,000 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Hernia Incisional
Assessment of Intra-abdominal Pressure During the Perioperative Period of Hernia Repair
Thousands of patients worldwide undergo abdominal surgery every day; 2-11% of laparotomies will progress to an incisional hernia, particularly midline laparotomies, which are associated with higher hernia rates, reaching up to…
- Trial name
- PRESSEVENT (NCT07531615)
- Testing
- Peroperative abdominal pressures measures
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Botulinum Toxins, Type A, Hernia
The Effects of Preoperative Botulinum Toxin A Injection on Respiratory System Function
Hernias are common complications post-abdominal surgeries, often leading to significant issues such as "loss of domain," where organs shift permanently, reducing abdominal cavity capacity.
- Trial name
- NCT06485440
- Testing
- Dysport 300 UNT Injection
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Swissmed Hospital
Ventral Incisional Hernia
Gentrix™ Versus Biological or Prosthetic Mesh
The hypothesis for this study is complex incisional hernia repair using the separation of components technique reinforced with retrorectus placement of Gentrix™ Surgical Matrix will lead to fewer incisional hernia recurrences and…
- Trial name
- NCT03034213
- Testing
- Gentrix™ Surgical Matrix (Treatment), Permacol, Parietex, Progrip, Strattice Perforated, or Surgimend (Control)
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of South Florida
Hernia, Hernia Abdominal Wall
Occupational Claims Due to Hernia
This study examines recognized occupational hernia claims using existing national administrative records. The purpose is to describe how often hernia-related occupational claims occur and to evaluate their distribution according…
- Conditions
- Hernia, Hernia Abdominal Wall, Hernia Incisional
- Trial name
- Hernia claims (NCT07831005)
- Where
- Israel
- Volunteers
- 4,500 people
- Sponsor
- Sergio Gabriel Susmallian
Incisional Hernia of Midline of Upper Abdomen, Incisional Hernia of Midline of Lower Abdomen
Double Mesh Modification of Incisional Hernia Can be Effective Without Severe Local Complications
22 patients of incisional hernia underwent treatment by double mesh modification of the original Chevrel's technique the primary outcome was recurrence, skin necrosis secondery out come was pain hematoma seroma
- Conditions
- Incisional Hernia of Midline of Upper Abdomen, Incisional Hernia of Midline of Lower Abdomen, Incisional Hernia of Midline of Abdomen
- Trial name
- NCT04166201
- Testing
- double mesh hernioplasty with modified chevrel's technique
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Zagazig University
Incisional Hernia
Incisional Hernia Repair With Mesh at Waitemata District Health Board - A 15 Year Retrospective Cohort Study'
A retrospective review of all incisional hernia repairs at North Shore Hospital (NSH), Auckland, NZ was performed between January 2004 and July 2019.
- Trial name
- NCT05482139
- Testing
- Incisional hernia repair with mesh
- Volunteers
- 718 people
- Sponsor
- Waitemata District Health Board
Colorectal Neoplasms, Parastomal Hernia
Longitudinal Incision Versus Cruciate Incision in the Construction of an End Colostomy
TITLE: "Incidence of parastomal hernia: Randomized clinical trial comparing the longitudinal fascial incision (" Hepworth hitch ") vs. cruciate incision in the exteriorization of a end colostomy ".
- Conditions
- Colorectal Neoplasms, Parastomal Hernia, Colostomy Stoma
- Trial name
- LONGCROSS (NCT04397783)
- Testing
- construction of an end colostomy
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Donostia