Clinical trials: Hernia, Incisional
Postoperative Hernia
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR)
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Trial name
- (PROTOP-PAR) (NCT05508152)
- Testing
- Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital de Granollers
Hernia, Incisional Hernia
"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic
"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture…
- Trial name
- 36P (NCT02137018)
- Testing
- PPL fixation by BP, PPL mesh
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Incisional Hernia Repair
Prospective Evaluation of Laparoscopic and Open Incisional Hernia Repair: a Multicenter Cohort Study
Nowadays incisional hernia are primarily repaired using prosthetic meshes. In Switzerland such meshes are mainly implanted via open or laparoscopic approach.
- Trial name
- IHR_SALTC (NCT01280370)
- Testing
- Abdominal surgery
- Where
- Switzerland
- Volunteers
- 371 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Laparotomy, Suture; Complications, Mechanical
DuraMesh Laparotomy Study
This is a multisite randomized control proof-of-concept trial to evaluate the safety of Duramesh laparotomy closure in the trauma and emergency laparotomy setting.
- Conditions
- Laparotomy, Suture; Complications, Mechanical, Hernia Incisional
- Trial name
- NCT03966768
- Testing
- Duramesh suturable mesh for laparotomy closure, Conventional suture for laparotomy closure
- Sponsor
- Mesh Suture Inc.
Incisional Hernia
Long Term Results of Randomized Prospective Comparison of Onlay and Sublay Mesh Repair Techniques for Incisional Hernia
Randomised prospective comparison of onlay and sublay mesh repair techniques in incisional hernia
- Trial name
- IH01 (NCT02314091)
- Testing
- onlay mesh hernioplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Meram State Hospital
Inguinal Hernia, Femoral Hernia
Detailed Pain Pattern After Laparoscopic Inguinal Hernia Repair
Pain after laparoscopic groin hernia repair consist of different pain components (overall pain, shoulder pain, incisional pain and visceral pain).
- Trial name
- NCT01105039
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Zealand University Hospital
Incisional Hernia
The Effect of Postoperative Abdominal Binder to Improve Outcomes After Incisional Hernia Repair
Postoperative seroma formation is one of the most common complications after ventral hernia repair with mesh. Although some seromas may not have clinical impact postoperative seroma formation often causes pain and discomfort and…
- Trial name
- INSAB (NCT01776775)
- Testing
- Abdominal binder
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital
Ventral Incisional Hernia
The SymCHro - Observational Registry Study for Symbotex™ Composite Mesh in Ventral Hernia Repair
The aim of this Observational Registry Study is to assess the short- and long-term clinical outcomes following the use of Symbotex™ Composite Mesh in primary and incisional abdominal wall hernia surgeries by open or laparoscopic…
- Trial name
- SymCHro (NCT02206828)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Medtronic - MITG
Incisional Hernia
Incisional Hernia Prevention: Risk-benefit From a Patient's Perspective
Incisional Hernia (IH) is a common complication of abdominal surgery and causes serious morbidity to patients. IH formation is multifactorial and its risk varies from patient to patient.
- Trial name
- INVITE (NCT05384600)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Cardiff and Vale University Health Board
Ventral Hernia, Incisional Hernia
Titanium vs Absorbable Tacks for Mesh Fixation in Laparoscopic Incisional and Ventral Hernia Repair
Background: Laparoscopic repair of ventral hernias has gained popularity, since many studies and a recent meta-analysis have reported encouraging results and recurrence rates similar to open repair.
- Trial name
- NCT02076984
- Testing
- Laparoscopic incisional or ventral hernia repair
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Roma La Sapienza
Surgical Incision
The REBUILD Trial: Closure of the Abdominal Wall
The main objective of this clinical trial is to demonstrate the safety and efficacy of REBUILD when used to support abdominal wall closure after laparotomy.
- Trial name
- NCT05687942
- Testing
- REBUILD
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- AbSolutions Med Inc.
Rectum Cancer
PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure
This study compares a synthetic mesh and biological implant in prevention of incisional hernia after loop-ileostomy closure.
- Trial name
- NCT03445936
- Testing
- Parietene Macro, Permacol
- Where
- 4 sites in Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Laparoscopic Colectomy
Incisional Hernia After Midline Versus Transverse Extraction Incision in Laparoscopic Colectomy
Incisional hernia (IH) is a common complication of midline laparotomy. Despite the hope that laparoscopic colon resection would result in fewer incisional hernias, prospective studies demonstrate a similar incidence to open…
- Trial name
- NCT01247389
- Testing
- laparoscopic colectomy
- Where
- Canada
- Volunteers
- 165 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Incisional Hernia, Ventral Hernia
Watchful Waiting of Incisional Hernias
This study is being conducted to gain a better understanding of the quality of life for patients with a diagnosis of primary and recurrent incisional hernias and 1) who decline to have surgery to repair the hernia or 2) patients…
- Conditions
- Incisional Hernia, Ventral Hernia, Umbilical Hernia
- Trial name
- NCT00351455
- Testing
- smoking cessation, tighter diabetic control, diet and exercise program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Incisional Hernia
Onlay Versus Sublay Mesh in Incisional Hernia
Onlay versus Sublay Mesh hernioplasty in management of incisional Hernia Comparative prospective study (Short term outcomes)
- Trial name
- NCT06197854
- Testing
- Hernioplasty
- Volunteers
- 40 people
- Sponsor
- Assiut University
Study of Practices of Surgeons on Surgical Management of Asymptomatic Hernias, Comparison With International Recommendations
Consensus in Surgical Community for Asymptomatic Abdominal Wall and Incisional Hernias
Hernia pathology is one of the leading causes of surgery worldwide. For asymptomatic patients, surgery remains questionable. Although there are new European recommendations, the practice of digestive surgeons regarding the…
- Trial name
- NCT04434573
- Testing
- Observation study
- Where
- France
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Incisional Hernia, Malignancy
Risk Factors for Development of Incisional Hernia in Transverse Incisions
RESEARCH PROJECT OBJECTIVES The aim of this planned study is to evaluate factors, with particular reference to surgical technique of abdominal closure, accumulation of advanced glycation end products, and collagen content in the…
- Trial name
- NCT03561727
- Testing
- Mass closure technique, Layered closure technique
- Where
- Poland
- Volunteers
- 392 people
- Sponsor
- Medical University of Warsaw
Incisional Hernias
Prophylactic Mesh Implantation for the Prevention of Incisional Hernia
Incisional hernias are primarily repaired using prosthetic meshes. In Switzerland such meshes are mainly implanted via open or laparoscopic approach.
- Trial name
- ProphMesh (NCT01203553)
- Testing
- Abdominal surgery
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Suture Size, Incisional Hernia
The Suture Size in Laparotomy Wound Closure to Prevent Post-operative Complications
Background: Incisional hernia is a common complication of midline laparotomy, and it is associated with high morbidity and high costs. Suture size used in the closure of the abdominal wall fascia was not studied independently.
- Trial name
- NCT05474677
- Testing
- closure of the abdominal fascia
- Where
- Oman
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Raya Al shaaibi
Postoperative Pain, Complications
Laparoscopic Versus Open Incisional Hernia Repair
Primary closure of incisional hernia without the use of a mesh shows recurrence rates of up to 54%. If a mesh is used, the defect can be closed tension-free. Using this method, recurrence rates have been reduced to 8-21%.
- Conditions
- Postoperative Pain, Complications, Recurrence
- Trial name
- COLIBRI (NCT01420757)
- Testing
- incisional hernia repair
- Volunteers
- 206 people
- Sponsor
- Erasmus Medical Center