Clinical trials: Hernia, Inguinal
Inguinal Hernias
Inguinal Hernia Management: Watchful Waiting vs. Tension-Free Open Repair
Purpose: To determine if observation (watchful waiting is a safe alternative to routine repair of asymptomatic inguinal hernias in adult males.
- Trial name
- NCT01922674
- Testing
- Standard open tension-free inguinal hernia repair with mesh
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Creighton University
Inguinal Hernia
Anterior Transversalis Fascia Approach Versus Preperitoneal Space Approach for Inguinal Hernia Repair in Residents
To investigate the advantages and disadvantages of the anterior transversalis fascia approach versus the preperitoneal approach for inguinal hernia repair in residents from northern China regarding common postoperative…
- Trial name
- NCT02984917
- Testing
- Anterior transversalis fascia approach, Preperitoneal space approach
- Where
- 9 sites in China
- Volunteers
- 2,000 people
- Sponsor
- The Fourth Affiliated Hospital of China Medical University
Hernia, Inguinal
Pain and Quality of Life After Inguinal Hernia Repair: Laparoscopic Versus Open Repair.
This investigation will be a double-armed, randomized prospective study designed to compare open (Lichtenstein Technique) versus laparoscopic (TAPP) repair of primary unilateral inguinal hernia.
- Trial name
- QoL-TAPP (NCT04211142)
- Testing
- Laparoscopic Transabdominal Preperitoneal Inguinal Hernia Repair (TAPP repair), Open Inguinal Hernia Repair (Lichtenstein repair)
- Where
- Spain
- Volunteers
- 216 people
- Sponsor
- Hospital Clinic of Barcelona
Inguinal Hernia
The Efficacy of Transversalis Fascia Plane Block in Pediatric Inguinal Hernia Repair
In patients undergoing lower abdominal surgery, postoperative pain management is frequently provided with systemic opioids use or neuraxial methods.
- Trial name
- NCT04272320
- Testing
- Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Persistent Postherniotomy Pain
Pain After Deep Electrical Stimulation in the Groin in Pain Free Subjects
Sensory disturbances in persistent postherniotomy pain, include hyperalgesia from deeper structures as well as the skin. Whether this is one combined pain syndrome, where for instance deep pain leads to cutaneous hyperalgesia, or…
- Trial name
- HADES-1 (NCT01701427)
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery
Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery
The primary objective of this study is to evaluate the effects of preemptive intravenous ibuprofen administration on delayed neurocognitive recovery (dNCR), postoperative pain management, and the overall quality of recovery in…
- Conditions
- Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery, Postoperative Pain, Neuroinflammation
- Trial name
- IBU-COG (NCT07424001)
- Testing
- Ibuprofen (400 mg x 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mehmet Çiğdem
Inguinal Hernia
ProGrip Mesh Repair vs Lichtenstein Operation
The purpose of this trial is to compare clinical outcomes and to analyze cost-effectiveness following self-gripping, sutureless Parietex ProGrip Mesh to traditional Lichtenstein Operation with lightweight polypropylene mesh.
- Trial name
- NCT02748629
- Testing
- Covidien Parietex ProGrip Self-Fixating Mesh, Lightweight Polypropylene Mesh (<38g/m2 after absorption)
- Where
- Poland
- Volunteers
- 143 people
- Sponsor
- Regional Health Center in Kartuzy, Poland
Hernia, Inguinal
Comparing Bi-level and Single-level ESP Block for Open Inguinal Hernia Repair
The goal of this clinical trial is to compare the effects of single-level and bi-level erector spinae plane block in open inguinal hernia repair surgery.
- Trial name
- NCT06155253
- Testing
- Erector spinae plane block
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hospital Authority, Hong Kong
Inguinal and Ventral Hernia Repair by Sublay, Underlay and IPOM Mesh Fixation
Effectiveness, Appropriateness and Safety of GLUTACK-Glubran Tiss 2 Surgical Glue Compared to GLUTACK-Glubran 2 Device System for Mesh Fastening in Laparoscopic and Robotic Hernia Surgery
This pre-market, prospective, randomized, non-inferiority clinical study was designed to evaluate the safety and performance/effectiveness of Glutack-Glubran® Tiss 2 system compared to Glutack-Glubran® used for mesh fixation in…
- Trial name
- AGluTHeMFix (NCT06462066)
- Testing
- Experimental medical device, Comparator medical device
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- GEM SRL
Inguinal Hernia, Postoperative Pain
Postoperative Effects of TAP Block Versus QLB Type 2 Block
This study compares analgesic effectiveness of transversus abdominis plane block and quadratus lumborum block type 2 in open hernia repair surgery. All of the patients will receive routine intravenous analgesic regimen.
- Trial name
- NCT03126084
- Testing
- Acetaminophen, 0.25% Bupivacaine, 0.5% Bupivacaine+Glucose
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Inguinal Hernia, Indirect, Surgery
Laparoscopic High-Ligation Repair of Indirect Inguinal Hernias in Adults
Inguinal hernia surgery has undergone significant and extensive transformation, including the advent of tissue-based repairs and later, tension-free repairs with the acceptance of prosthetic mesh.
- Conditions
- Inguinal Hernia, Indirect, Surgery, Postoperative Pain, Recurrence
- Trial name
- NCT06120114
- Testing
- Modified percutaneous internal ring suturing
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Inguinal Hernia
Comparison of Dexmedetomidine and Midazolam for Intra-op Sedation in TIVA in Children Undergoing Inguinal Hernia Repair
To compare dexmedetomidine and midazolam for intra-op sedation in TIVA in children undergoing inguinal hernia repair. The results of the study if found significant will guide the anesthetist in appropriate choice and dose of…
- Trial name
- NCT05337085
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Sheikh Zayed Medical College
Analgesia, Inguinal Surgery
"Comparison of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block for Pediatric Inguinal Surgeries"
This study is designed to compare the analgesic effectiveness of caudal analgesia to ilioinguinal regional analgesia techniques in children undergoing inguinal surgeries.
- Conditions
- Analgesia, Inguinal Surgery, Undescended Testes, Hydrocele
- Trial name
- CAUCIN (NCT05558748)
- Testing
- USG-guided Caudal block, USG-guided Ilioinguinal/Iliohypogastric block
- Where
- Oman
- Volunteers
- 128 people
- Sponsor
- Sultan Qaboos University
Inguinal Hernia, Premature Birth of Newborn
Timing of Inguinal Hernia Repair in Premature Infants
The purpose of this study is to determine whether early (before NICU discharge) or late (55-60 weeks post-menstrual age) inguinal hernia repair is safer for premature infants who have an inguinal hernia.
- Trial name
- NCT01678638
- Testing
- IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
- Where
- 40 sites in United States
- Volunteers
- 338 people
- Sponsor
- Vanderbilt University Medical Center
İnguinal Hernia, Complication,Postoperative
Post-Surgical Outcomes of Conventional vs 3-Point Mesh Fixation in Lichtenstein Repair: An RCT
This is a single-center, parallel-group randomized controlled trial conducted in 2025-2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi.
- Conditions
- İnguinal Hernia, Complication,Postoperative, Pain, Postoperative
- Trial name
- COMET (NCT07334548)
- Testing
- 3-point mesh fixation, Conventional Mesh Fixation
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Sahar Mughis
Hernia, Inguinal, Pain, Postoperative
Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair
Surgical intervention to treat a inguinal hernia is a very common pediatric surgical procedure, often performed using an inguinal incision.
- Trial name
- NCT03041948
- Testing
- Ilioinguinal/iliohypogastric nerve block, Caudal-epidural nerve block, Acetaminophen
- Where
- 2 sites in Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Inguinal Hernias
Evaluation of the Efficacy of Electromagnetic Therapy on Postoperative Surgical Pain After Uni- and Bilateral Inguinal Hernia Repair.
A monocentric interventional randomized placebo controlled trial evaluating the efficacy of the post surgical and wound care recovery kit.
- Trial name
- ELEFANT (NCT01842204)
- Testing
- Magnetic field therapy device, Non magnetic field therapy device.
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University Hospital, Ghent
Hernia, Inguinal, Chronic Postoperative Pain
Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain
The management of chronic pain after inguinal hernia surgery presents unique challenges. Ilioinguinal nerve blocks are often used in the initial treatment of this disease.
- Trial name
- NCT05386693
- Testing
- Ilioinguinal nerve block
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Postoperative Pain
QIPB in Inguinal Hernia
Inguinal hernia repair is one of the most commonly performed surgical procedures. It is generally performed under regional anesthesia techniques, such as local anesthesia, peripheral nerve blocks, or neuraxial anesthesia (spinal…
- Trial name
- NCT06862609
- Testing
- Quadro iliac plane block, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Konya City Hospital
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University