Clinical trials: Hernia Incisional
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Hernia
Repair of Infected or Contaminated Hernias
This is a prospective, multicenter, interventional, observational, open label, single arm, longitudinal evaluation of ventral incisional hernia repair using LTM in contaminated or infected sites.
- Trial name
- RICH (NCT00617357)
- Testing
- LTM (Strattice Reconstructive Tissue Matrix)
- Where
- 15 sites in United States
- Volunteers
- 83 people
- Sponsor
- LifeCell
Incisional Hernia/Prevention and Control
Prometheus: Prophylactic Mesh After OLtx for Hernia Reduction Study.
A multicenter prospective, consecutive case series study, on the use of a bio-absorbable mesh for prevention of incisional hernia, in high risk patients, after orthotopic liver transplantation.
- Trial name
- PROMETHEUS (NCT07744230)
- Testing
- mesh
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Incisional Hernia Occurence
Primary Mesh Closure of Abdominal Midline Wounds
Incisional hernia is the most frequently seen long term complication in surgery causing much morbidity and even mortality in patients.
- Trial name
- PRIMA (NCT00761475)
- Testing
- mesh supported closure, primary closure
- Where
- 12 sites in Austria, Germany and 1 more
- Volunteers
- 480 people
- Sponsor
- Erasmus Medical Center
Incisional Hernia, Malignancy
Risk Factors for Development of Incisional Hernia in Transverse Incisions
RESEARCH PROJECT OBJECTIVES The aim of this planned study is to evaluate factors, with particular reference to surgical technique of abdominal closure, accumulation of advanced glycation end products, and collagen content in the…
- Trial name
- NCT03561727
- Testing
- Mass closure technique, Layered closure technique
- Where
- Poland
- Volunteers
- 392 people
- Sponsor
- Medical University of Warsaw
Incisional Hernia, Large Incisional Hernia
Retrospective Analysis on Large Incisional Hernia in High Risk Patients
Large incisional hernia (LIH) is a challenging condition where the abdominal wall is hopelessly compromised. Nowadays the best treatment option in this particularly frail subset of patients is a major issue.
- Trial name
- NCT04801394
- Testing
- hernioplastic and insertion of FLaPp® composite mesh
- Volunteers
- 43 people
- Sponsor
- University of Campania Luigi Vanvitelli
Incisional Hernia, Pelvic Cancer
Trial of Collagen Mesh for Prevention of Ventral Hernia After Surgery for Advanced Pelvic Cancer
The aim of the present project is to investigate whether use of biological mesh at the donor site of the rotation flap in closure of the abdominal wall reduce the frequency of incisional hernia formation compared to the usual…
- Trial name
- VRAM (NCT00647569)
- Testing
- Mesh repair, Conventional facial closure
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
Laparotomy, Suture; Complications, Mechanical
DuraMesh Laparotomy Study
This is a multisite randomized control proof-of-concept trial to evaluate the safety of Duramesh laparotomy closure in the trauma and emergency laparotomy setting.
- Conditions
- Laparotomy, Suture; Complications, Mechanical, Hernia Incisional
- Trial name
- NCT03966768
- Testing
- Duramesh suturable mesh for laparotomy closure, Conventional suture for laparotomy closure
- Sponsor
- Mesh Suture Inc.
Incisional Hernia, Parastomal Hernia
Hernia Prevention in Stomas
Knowing that the risk of stoma associated herniation (parastomal or incisional) is 30-50% and the associated morbidity significant, standard placement of a prophylactic mesh upon stoma creation might prevent parastomal (or…
- Trial name
- NCT00907842
- Testing
- Parietex Parastomal Mesh
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Marc Schreinemacher
Incisional Hernia Repair
Prospective Evaluation of Laparoscopic and Open Incisional Hernia Repair: a Multicenter Cohort Study
Nowadays incisional hernia are primarily repaired using prosthetic meshes. In Switzerland such meshes are mainly implanted via open or laparoscopic approach.
- Trial name
- IHR_SALTC (NCT01280370)
- Testing
- Abdominal surgery
- Where
- Switzerland
- Volunteers
- 371 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ventral Hernia, Umbilical Hernia
Preperitoneal Umbilical Mesh Area
The aim of this study is to measure the mesh shrinkage and the visualization of the mesh with MRI scan at 1 month and 13 months after robot assisted preperitoneal hernia repair using the visible CICAT mesh (Dynamesh®).
- Conditions
- Ventral Hernia, Umbilical Hernia, Ventral Incisional Hernia
- Trial name
- PUMA (NCT05576753)
- Testing
- Hernia repair
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Incisional Hernia
The Effect of Postoperative Abdominal Binder to Improve Outcomes After Incisional Hernia Repair
Postoperative seroma formation is one of the most common complications after ventral hernia repair with mesh. Although some seromas may not have clinical impact postoperative seroma formation often causes pain and discomfort and…
- Trial name
- INSAB (NCT01776775)
- Testing
- Abdominal binder
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital
Incisional Hernia, Extracellular Matrix Alteration
Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology
This study included patients who underwent surgical treatment for incisional hernia and non-hernia conditions. Surgical specimens were collected for transcriptome sequencing to obtain the gene expression list.
- Trial name
- NCT06366581
- Testing
- Transcriptomic analysis
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fudan University
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Obesity, Morbid, Hernia Incisional
TROCAR SITE HERNIA AFTER LSG
Today, laparoscopic sleeve gastrectomy (LSG) has become the most frequently performed bariatric surgical method. One of the complications seen after LSG is trocar site hernia (TSH).
- Trial name
- NCT04849403
- Testing
- CTSP
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hernia, Inguinal
SIL-TEP vs TEP for Inguinal Hernia Repair in Day Surgery
This study aim to compare the efficacy and safety of Single incisional Laparoscopic Total Extraperitoneal(SIL-TEP) Inguinal Hernia Repair and traditional Laparoscopic Total Extraperitoneal(TEP) Inguinal Hernia Repair in day…
- Trial name
- NCT02415543
- Testing
- SIL-TEP Inguinal Hernia Repair, TEP Inguinal Hernia Repair
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TAO CHEN
Incisional Hernia
Incidence and Risk Factors for TSIH
Trocar site incisional hernia (TSIH) is the most frequent complication associated to laparoscopic surgery. Few studies currently describes its real prevalence or risk factors.
- Trial name
- TSIHi (NCT04410744)
- Testing
- Ultrasonographic examination
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Hospital de Mataró
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Incisional Hernia
PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM)
To evaluate the efficacy of the use of swine dermal collagen prosthesis implanted preperitoneally as a prophylactic procedure against incisional hernia in patients operated in urgency/emergency setting in contaminated/infected…
- Trial name
- PROPHYBIOM (NCT02277262)
- Testing
- Biological swine dermis not cross-linked prosthesis positioning in incisional hernia prevention, Direct suture of the anterior abdominal wall fascia
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII