Clinical trials: Hernia Repair
Umbilical Hernia
Visible vs. Non-Visible Mesh in Underlay Positon After Repair of Umbilical Hernias
The purpose of this study is to determine the exact position of a mesh which is placed in underlay position in umbilical hernia in vitro.
- Trial name
- NANEP (NCT03200405)
- Testing
- DynaMeshVisible, DynaMeshCICAT
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Wuerzburg University Hospital
Postoperative Pain, Chronic Pain
Chronic Postoperative Pain After Laparoendoscopic Groin Hernia Repair
The study attempts to quantify the relative risks for chronic postoperative inguinal pain (CPIP) depending on different combinations of mesh and mesh fixation.
- Trial name
- NCT04838028
- Testing
- TEP, TAPP, Other or unspecified laparoendoscopic groin hernia repair
- Volunteers
- 15,360 people
- Sponsor
- Karolinska Institutet
Ilioinguinal Nerve Section, Pain Prevention
Prophylactic Ilioinguinal Neurectomy During Open Tension-Free Inguinal Hernia Repair
postoperative chronic inguinal pain is a common postoperative complication after open inguinal hernia repair. Chronic inguinal pain is a common complication following open inguinal hernia repair.
- Conditions
- Ilioinguinal Nerve Section, Pain Prevention, Hernioplasty
- Trial name
- NCT06327763
- Testing
- ilioinguinal nerve section
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Incidence of Mesh Infection In Hernioplasty
Incidence Of Mesh Infection After Hernioplasty In Obstructed and Strangulated Hernia Using Proline Mesh and Sutures
The primary aim of this study is to detect incidence of mesh infection in cases presented with obstructed or strandulated hernia.A prospective controlled study will be carried out after obtaining written informed consent from all…
- Trial name
- NCT05775276
- Testing
- Proline mesh in hernioplasty
- Volunteers
- 60 people
- Sponsor
- Assiut University
Inguinal Hernia, Convalescence
Pain and Convalescence After Laparoscopic Groin Hernia Repair
The investigators want to identify limiting factors for short convalescence after laparoscopic groin hernia repair. Before the operation patients are given intensive structured information about one day´s convalescence.
- Trial name
- Lap-Lyske (NCT00962338)
- Testing
- Information
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Zealand University Hospital
Postoperative Complications
TAPP Inguinal Hernia Repair With Self-fixating Parietex™ ProGrip™ Mesh
The objective of this retrospective study is to evaluate the postoperative clinical outcomes at discharge, 1 month and 12 months, associated with the use of Parietex™ ProGrip™ in Laparoscopic Transabdominal preperitoneal inguinal…
- Trial name
- NCT01481376
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Medtronic - MITG
Pain, Postoperative, Anesthesia, Local
Improving Pain Relief Following Laparoscopic Ventral Hernia Repair
Aim The general aim of this study is to improve post-operative pain and reduce morphine consumption following laparoscopic ventral hernia repair (LVHR).
- Conditions
- Pain, Postoperative, Anesthesia, Local, Hernia, Ventral, Laparoscopy
- Trial name
- NCT02785276
- Testing
- AutoFuser Pain Pump, Ropivacaine, Normal Saline (0.9%)
- Where
- New Zealand
- Sponsor
- University of Auckland, New Zealand
Hernia, Ventral
Primary Fascial Closure With Laparoscopic Ventral Hernia Repair: A Randomized Controlled Trial
This study is comparing the outcomes patients undergoing LVHR, PFC as opposed to a bridged repair with assessment of patient reported satisfaction and function at 6 months of follow-up.
- Trial name
- NCT02363790
- Testing
- LVHR PFC, Bridging LVHR
- Where
- 5 sites in United States
- Volunteers
- 189 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ventral Hernia
Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled Trial
The primary objective of the study is to demonstrate that hernia recurrence (VH) repair with non absorbable mesh concomitant to Bariatric Surgery (BS) decreases the risk of VH, with or without surgical repair, during the first…
- Trial name
- BeSURE (NCT05488288)
- Testing
- Mesh repair, Suture repair
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hiatal Hernia With Gastroesophageal Reflux Disease
Comparison of Laparoscopic Nissen Fundoplication and Hill-Snow Repair for Hiatus Hernia With Endoscopic Evaluation
The goal of this clinical trial is to compare the clinical efficacy and safety of laparoscopic Nissen fundoplication (LNF) versus laparoscopic Hill-Snow repair (LHS) in the management of patients with congenital hiatus hernia, to…
- Trial name
- NCT07387042
- Testing
- Laparoscopic Hill-Snow repair, Laparoscopic Nissen Fundoplication
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Rectocele
STARR Trans-anal Resection Versus Vaginal Rectocele Repair Using Elevate: Effects on Defecatory Function
The primary objective of this study is to compare the function results between two methods for surgically repairing rectoceles: vaginal versus endo-anal surgery.
- Trial name
- RectoVerso (NCT01257659)
- Testing
- STARR rectocele repair, Elevate mesh rectocele repair
- Where
- 6 sites in France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bilateral Inguinal Hernia
Laparoscopic Versus Open Mesh Repair of Bilateral Primary Inguinal Hernia
The best approach for simultaneous repair of bilateral inguinal hernia is controversial. The aim of this study is to compare the outcomes after laparoscopic versus open mesh repair of bilateral primary inguinal hernia
- Trial name
- NCT04437784
- Testing
- Laparoscopic Trans-Abdominal Pre-Peritoneal, Open pre-peritoneal repair, Bilateral Lichtenstein repair
- Volunteers
- 180 people
- Sponsor
- Alexandria University
Rectocele; Female, Rectocele and Incomplete Uterine Prolapse
3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center Study
The aim is to compare proximate and remote results of 3D and conventional 2D laparoscopic interventions in terms of efficacy and safety in treatment of symptomatic rectocele and rectal prolapse.
- Conditions
- Rectocele; Female, Rectocele and Incomplete Uterine Prolapse, Rectocele and Complete Uterovaginal Prolapse, Rectal Prolapse
- Trial name
- LARC (NCT04817150)
- Testing
- Laparoscopic ventral mesh rectopexy
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexander Khitaryan
Ventral Hernia
Prospective Clinical Observational Cohort Study to Evaluate the Use of a Tissue Separating Mesh (Proceed®) in Laparoscopic Ventral Hernia Repair
1. General: antibiotic prophylaxis: cefazoline (Cefacidal™) 2 gram iv administered 30 minutes before surgery 2. Laparoscopic surgery at least 5 cm overlap (mesh diameter should exceed hernia size by at least 10 cm) with or…
- Trial name
- NCT00572962
- Testing
- use of a tissue separating mesh (Proceed®) in Laparoscopic Ventral hernia repair
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- University Hospital, Ghent
Inguinal Hernia
Repair of Groin Hernias After Abdominal Prostatectomy With Robotic TAPP
This retrospective study investigates if robotic assisted groin hernia repair in patients who previously underwent abdominal prostatectomy has an equal or more favorable clinical outcome, compared to open repair in those patients.
- Trial name
- RAPrTAPP (NCT04718597)
- Testing
- Robotic assisted inguinal hernia repair, Open inguinal hernia repair
- Where
- Belgium
- Volunteers
- 43 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Ventral Hernia
Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
A ventral hernia happens when the muscles in the front of your belly become weak and let organs push through, causing a bulge. If it gets worse, intestines can slip into the bulge, leading to serious pain and health problems.
- Trial name
- NCT07226791
- Testing
- AGN-151607-DP
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- AbbVie
Hernia, Inguinal
Quality of Life After Shouldice Repair
This research project aims to assess the quality of life (QOL) and pain/discomfort experienced by patients who have undergone primary inguinal hernia repair at Shouldice Hospital.
- Trial name
- QoL (NCT06037304)
- Testing
- no intervention
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Shouldice Hospital
Pain, Postoperative
Phase 3 Study of Efficacy and Safety of the XaraColl® Bupivacaine Implant After Hernioplasty
This is a Phase 3, multicenter, randomized, double-blind, parallel-group, placebo-controlled efficacy and safety study of postoperative pain in adults who are scheduled for unilateral inguinal hernioplasty via open laparotomy…
- Trial name
- MATRIX-2 (NCT02525133)
- Testing
- XaraColl
- Where
- 24 sites in United States
- Volunteers
- 319 people
- Sponsor
- Innocoll
Abdominal Hernia, Abdominal Surgery
Versius or Laparoscopic Abdominal Hernia REpair
This trial will compare laparoscopic and robotic-assisted abdominal hernia repairs, using the Versius® system. We will initially aim to recruit 60 patients (20 patients in the laparoscopic arm and 40 in the robotic arm) in order…
- Trial name
- VOLARE (NCT05253586)
- Testing
- Laparoscopic, Robotic
- Sponsor
- Joanne Turner
Hernia
Repair of Infected or Contaminated Hernias
This is a prospective, multicenter, interventional, observational, open label, single arm, longitudinal evaluation of ventral incisional hernia repair using LTM in contaminated or infected sites.
- Trial name
- RICH (NCT00617357)
- Testing
- LTM (Strattice Reconstructive Tissue Matrix)
- Where
- 15 sites in United States
- Volunteers
- 83 people
- Sponsor
- LifeCell