Clinical trials: Herniated Disk Lumbar
Lumbar Disc Herniation
Trial to Show Non-inferiority / Superiority of an Endoscopic Transforaminal Discectomy to Standard Microdiscectomy
This study compares an endoscopic transforaminal surgical technique for the treatment of a herniated disc to the standard microsurgical procedure. Clinical parameters as well as health economy will be assessed.
- Trial name
- TESCORT (NCT01622413)
- Testing
- joimax TESSYS, Microdiscectomy
- Where
- 3 sites in Austria, Germany
- Sponsor
- Joimax GmbH
Degenerative Disc Disease, Chronic Low-back Pain
"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)
This study will be a prospective, open-label, multi-center study including 72 patients that will collect additional safety and efficacy data for the Spinal Stabilization Technologies PerQdisc Nucleus Replacement System.
- Trial name
- LOPAIN2 (NCT05508360)
- Testing
- PerQdisc Nucleus Replacement System
- Where
- 11 sites in Colombia, Costa Rica and 3 more
- Volunteers
- 72 people
- Sponsor
- Spinal Stabilization Technologies
Herniated Lumbar Disc
Postoperative Pain and Analgesic Use Following Lumbar Discectomy: A Comparative Study of Endoscopic Surgery and Open Surgery
The lifetime prevalence of lumbosacral radiculopathy is 3 to 5 percent. The most common cause is a lumbar disc herniation. In 10 to 20 percent of patients, medical treatment is insufficient, and surgery is recommended.
- Trial name
- DISCOPAIN (NCT07766031)
- Testing
- Endoscopic surgery, Open surgery
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Saint-Gregoire Private Hospital Center
Herniated Disk Lumbar, Fibromyalgia
Effect of Fibromyalgia on Outcomes of Transforaminal Epidural Steroid Injection Treatment in Lumbar Radicular Pain
Lumbar radicular pain is defined as low back and leg pain caused by inflammation in the affected nerve root due to various etiological factors.
- Trial name
- NCT05053217
- Testing
- transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Prolapsed Lumbar Disc, Prolapsed Cervical Disc
Patient Registry to Observe Outcomes Following Implantation of the VariLift Interbody Fusion Device
The registry has been designed as a prospective, observational program for patients undergoing lumbar or cervical fusion using VariLift device with the ultimate goal to aid in the development of strategic treatment pathways and…
- Conditions
- Prolapsed Lumbar Disc, Prolapsed Cervical Disc, Intervertebral Disc Degeneration, Spondylolisthesis, Grade 1
- Trial name
- NCT01944345
- Where
- 3 sites in United States
- Volunteers
- 69 people
- Sponsor
- Wenzel Spine
Intervertebral Disc Protrusion
Mulligan SNAG Technique in Individuals With Lumbar Intervertebral Disc Protrusion
This study aimed to examine the effects of the Mulligan SNAG mobilization technique, applied in addition to conventional physiotherapy on the structure of the intervertebral disc and physical functioning in patients diagnosed…
- Trial name
- NCT06521294
- Testing
- Mulligan SNAG mobilization tecnique, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Biruni University
Low Back Pain, Sciatica
Ultrasound-guided Lumbar Periradicular Injection: a Non Irradiating Infiltration Technique
We propose here to evaluate the precision of lumbar periradicular infiltration performed under a transverse ultrasound approach by performing a fluoroscopic control once the needle in the desired position.
- Conditions
- Low Back Pain, Sciatica, Disc, Herniated, Foraminal Hernia
- Trial name
- NCT03453775
- Testing
- Ultrasound guided periradicular lumbar infiltration, Fluoroscopy guided periradicular lumbar infiltration
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Pain, Lumbar Disc Herniation
The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation
This study will investigate whether two clinical tests can be used to diagnose and predict the outcome in patients with lumbar disc herniation undergoing surgery and non-surgery treatment.
- Conditions
- Pain, Lumbar Disc Herniation, Back Pain, Spinal Diseases
- Trial name
- NCT03832036
- Testing
- Paraspinal Mapping and Quantitative Sensory Pain Test
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Spine Centre of Southern Denmark
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Safety and Efficacy With NOVOCART® Disc Plus (ADCT) for the Treatment of Degenerative Disc Disease in Lumbar Spine
NOVOCART® Disc plus is being investigated to explore its clinical applicability, safety and efficacy in the repair of a herniated disc with an indication for an elective sequestrectomy, and of the adjacent degenerated disc, if…
- Trial name
- NDisc (NCT01640457)
- Testing
- NOVOCART® Disc plus, NOVOCART® Disc basic
- Where
- 10 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Tetec AG
Chronic LDH
Restoration of Sensorimotor Function in Middle-Aged Women With Chronic Lumbar Disc Herniation: The Effect of Pilates on Proprioception, Tibialis Anterior Strength, and Dynamic Balance
The aim of this study is to determine the effects of core stabilization-focused Pilates exercises on sensorimotor function in middle-aged women diagnosed with chronic lumbar disc herniation (LDH).
- Trial name
- Chronic LDH (NCT07515287)
- Testing
- Pilates Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Symptomatic Lumbar Disc Herniation, Symptomatic Grade I Lumbar Spondylolisthesis
Neurosurgery Patient Outcomes in Treating Spinal Disorders
The creation of a multi-center cooperative research group encompassing academic and community-based spinal practices . . .
- Trial name
- Neuropoint SD (NCT01220921)
- Testing
- Lumbar Discectomy, Single-level lumbar fusion
- Where
- 13 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- Greenwich Hospital
Lumbar Disc Herniation, Emergence Agitation
Magnesium Sulfate for Prevention of Emergence Agitation in Lumbar Disc Surgery
In this retrospective study, the effect of intraoperative magnesium sulfate infusion on the incidence of postoperative emergence agitation was evaluated in adult patients who underwent elective lumbar microdiscectomy under…
- Conditions
- Lumbar Disc Herniation, Emergence Agitation, Magnesium Sulfate
- Trial name
- NCT07139847
- Testing
- Magnesium Sulfate Infusion, 0.9% Saline Infusion
- Volunteers
- 70 people
- Sponsor
- Ondokuz Mayıs University
Low Back Pain
Treatment of Chronic Low Back and Lower Extremity Pain
1. To demonstrate clinically significant improvements in patients undergoing lumbar interlaminar epidurals. Improvement will be assessed in relation to the clinical outcome measures of pain and function. 2.
- Trial name
- NCT00681447
- Testing
- Lumbar Interlaminar Epidural, Lumbar Interlaminar Epidural injection
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Lumbar Disc Herniation
A Prospective, Randomized, Multicenter Study to Demonstrate the Superiority of the Barricaid to Discectomy for Primary Lumbar Disc Herniation
A randomized study to demonstrate the superiority of the Barricaid® when used in conjunction with limited discectomy, compared to limited discectomy alone, with regard to preventing reherniation and the recurrence of pain or…
- Trial name
- NCT01283438
- Testing
- Barricaid, Standard of Care
- Where
- 21 sites in Austria, Belgium and 4 more
- Volunteers
- 554 people
- Sponsor
- Intrinsic Therapeutics
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Proprio Spine Measurement Tool
This study will prospectively collect data to evaluate the effectiveness of a novel intraoperative spinal measurement system to assist the surgeon with intraoperatively achieving pre-planned alignment-related parameters to the…
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Osteochondrosis
- Trial name
- NCT07023393
- Testing
- Intraoperative spinal measurement system
- Where
- United States
- Sponsor
- Duke University
Lumbar Disc Herniation, Radiculopathy Lumbar
Non-pharmacological Treatment and Pharmacological Treatment for Non-acute Lumbar Disc Herniation
This study is a 2-armed parallel, multi-centered, pragmatic clinical trial that compares the comparative effectiveness of non-pharmacological treatment and pharmacological treatment for non-acute lumbar disc herniation.
- Trial name
- NCT05003726
- Testing
- non-pharmacological treatment, pharmacological treatment
- Where
- 4 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Lumbar Disc Herniation
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation
Lumbar disc herniation compressed the nerve cause pain, numbness, weak legs called sciatica, which seriously decrease the quality of life and work efficiency.
- Trial name
- NCT05330806
- Testing
- Collagenase chemonucleolysis, Percutaneous endoscopic lumbar discectomy (PELD)
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shenzhen People's Hospital
Back Pain Lower Back, Magnetic Therapy
High Intensity Focused Electromagnetic Therapy on Pain and Quality of Life in Patients With Lumbar Disc Prolapse
Determine whether high intensity focused electromagnetic therapy has a significant effect on pain and quality of life in patients with lumbar disc prolapse.
- Trial name
- NCT07278596
- Testing
- High intensity focused electromagnetic therapy (HIFEMT), Stabilization exercise program
- Volunteers
- 60 people
- Sponsor
- Middle East University
Lumbal Disc Herniation
A Study Comparing Peloid Therapy and Hot Pack Treatment in Adults With Chronic Low Back Pain Caused by Lumbar Disc Herniation
The goal of this clinical trial is to compare the effectiveness of peloid therapy versus hot pack therapy in adults aged 18-50 with chronic lumbar disc herniation (LDH).
- Trial name
- NCT07087548
- Testing
- Peloid Therapy, Hotpack Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fenerbahce University
Lumbar Disk Herniation
Effectiveness of Lumbar Traction in Lumbar Disk Herniation
The purpose of this study is to compare the clinical outcome of medical treatment associated with lumbar traction and medical treatment alone in the treatment of lumbar disk herniation.
- Trial name
- NCT02793440
- Testing
- cortivazol treatment, lumbar traction
- Where
- France
- Volunteers
- 412 people
- Sponsor
- CHU de Reims