Clinical trials: Herniation, Disc
Lumbar Disc Herniation
Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine
This randomized controlled clinical trial is designed to evaluate the efficacy and safety of Bosinji on low back pain and radiating pain of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of…
- Trial name
- NCT03386149
- Testing
- Bosinji, Loxonine tab., Acupuncture
- Where
- 4 sites in South Korea
- Volunteers
- 74 people
- Sponsor
- Kyunghee University Medical Center
Chronic Low-back Pain, Herniated Disc
LISA Post Market Clinical Follow-Up Study: Documentation of Clinical Outcomes After Surgery With LISA Implant
The study is a post-market surveillance study of the Lumbar Implant for Stiffness Augmentation (LISA), a medical device, which is used to treat low-back pain that accompanies degenerative lesions of grades II, III, and IV…
- Conditions
- Chronic Low-back Pain, Herniated Disc, Degenerative Disc Disease, Lumbar Canal Stenosis
- Trial name
- LISA-PMCF (NCT04631133)
- Testing
- Lumbar Implant for Stiffness Augmentation (LISA)
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 136 people
- Sponsor
- BACKBONE
Lumbar Disc Herniation
QLB vs mTLIP for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves.
- Trial name
- NCT05217121
- Testing
- Quadratus Lumborum Block, Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Disc Herniation
Silent Lumbar Disc Herniation Syndrome
LDH is a common phenomenon that is often described in association with various pathological processes affecting the neuromuscular and locomotor systems.
- Trial name
- NCT06453499
- Testing
- Physical therapy
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Noha Khaled Shoukry
Lumbar Disc Herniation, Radiculopathy Lumbar
Efficacy and Safety of Electroacupuncture on Lumbar Disc Herniation with Radiculopathy
Lumbar disc herniation with radiculopathy (LDHR) is the local displacement of the intervertebral disc and its contents beyond the edge of the normal intervertebral disc space, resulting in pain, weakness or numbness in the muscle…
- Trial name
- NCT06611332
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Lumbar Disc Herniation
Strengthening Exercise and Activities of Daily Living Instructions for Patients With Lumbar Disc Herniation
Lumbar disc herniation (LDH) is one of the most common causes of mechanical low back pain (LBP) associated with radiating leg pain.
- Trial name
- NCT05021718
- Testing
- Strengthening exercises, Pharmacological therapy, Hot compression
- Where
- Bangladesh
- Volunteers
- 70 people
- Sponsor
- Chittagong Medical College
Instrument-assisted Soft Tissue Mobilization, Treatment
Investigation of The Effect of "Instrument-Assisted Soft Tissue Mobilization" in Individuals With Lumbar Disc Herniation
Instrument-assisted soft tissue mobilization is an instrument-assisted soft tissue mobilization technique. It consists of stainless steel instrument designed to adapt to various tissues/shapes/curves of the body.
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Treatment, Exercise, Pain
- Trial name
- NCT06529926
- Testing
- Observational, IASTM Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Lumbar Disc Herniation
A Biomechanical Study of the Lumbar Intervertebral Disc by Lever Positioning Manipulation
Purpose of Study: The purpose of this clinical trial is the clinical efficacy of different trigger modes of lever positioning manipulation (LPM) for the treatment of lumbar disc herniation (LDH).
- Trial name
- NCT06872918
- Testing
- Lever positioning manipulation, Cluster of pseudo-manipulators, Mechanics and kinematics data acquisition of unilateral wrenching patterns in lever positioning manipulation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Lumbar Disc Herniation
Effect of Pulsed Mode Radiofrequency as a Treatment of Lumbar Disc Related Radicular Pain on Tumor Necrotic Factor α Level
Lumbar radiculopathy is a term that describes symptoms of pain, numbness, and/or weakness that radiate along the sciatic nerve from the lower back to the buttocks and leg (1).
- Trial name
- NCT05288920
- Testing
- Radiofrequency pulsed mode on dorsal root ganglion combined with transforaminal steroids injection, Transforaminal injection of Steroids alone
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Herniated Disc, Radiculopathy
Slotted Hole Versus Fixed Hole C-Tek
The purpose of this study is to compare the fusion rates between the EBI, LLC C-Tek™ Anterior Cervical Plate, Slotted Hole Design versus the Fixed Hole Design.
- Conditions
- Herniated Disc, Radiculopathy, Spondylolysis
- Trial name
- NCT00585923
- Testing
- Fixed hole C-Tek™ Plate, Slotted hole C-Tek™ Plate
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Zimmer Biomet
Lumbar Spine Disease, Lumbar Disc Herniation
Perioperative Local Anesthesia Block in Spine Surgery
The purpose of the this study to evaluate the feasibility, safety, and efficacy of a fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon prior to lumbosacral surgery.
- Conditions
- Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT05094427
- Testing
- Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Columbia University
Lumbar Disc Disease, Lumbar Disc Herniation
Physiotherapy in Lumbar Disc Pathologies
The aim of this study is to compare the effectiveness of four physical therapy treatment approaches for lumbar region pathologies. Eighty volunteers who have back pain will be included in the study.
- Conditions
- Lumbar Disc Disease, Lumbar Disc Herniation, Low Back Pain, Mechanical, Low Back Strain
- Trial name
- NCT04061759
- Testing
- Effectiveness of four physical therapy approaches (soft tissue manual therapy, Kinesio® Taping techniques, stabilization exercises and reflex therapy) for treating lumbar disc pathologies.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Guven Health Group
Cervical Disc Herniation, Lumbar Disc Herniation
The Value of Short-term Pain Relief for the Prediction of Long-term Outcome After Cervical or Lumbar Nerve Root Infiltration
The purpose if this study is to assess the response to nerve root infiltration therapy in patients with cervical or lumbar disc herniations.
- Trial name
- InfStu (NCT01945554)
- Testing
- Cervical nerve root infiltration, Lumbar nerve root infiltration, Mephamesone
- Where
- 3 sites in Switzerland
- Volunteers
- 250 people
- Sponsor
- Holger Joswig
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Lumbar Disc Herniation
Plane Block vs Intravenous Patient Controlled Analgesia
Acute postoperative pain begins with surgical trauma and decreases with tissue healing. Untreatable postoperative pain is one of the most important problems due to the increase in respiratory, cardiac and thromboembolic…
- Trial name
- NCT04457986
- Testing
- Erector spina plane block (ESP), Modified thoracolumbar interfacial plane block (MTI), Intravenous patient controlled analgesia (IV-PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Diskapi Teaching and Research Hospital
Neuralgia, Sciatic
An Effect and Safety Observation on PELD Technique for Extraforaminal Disc Herniation at L5/S1
43% or so of far lateral lumbar disc herniation (FLLDH) occurred at L5/S1, however, the surgical treatment is still quite challenging.
- Trial name
- NCT03511456
- Testing
- PELD operation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Low Back Pain
Serum Cytokine Levels in Patients with Lumbal Disc Herniation and Effectiveness of Exercise
The aim of the study is to investigate serum cytokine levels and the efficacy of lumbar stabilization exercises in patients with lumbar disc herniation with and without neurological deficits.
- Trial name
- NCT04912388
- Testing
- Lumbal stabilization excercises, Conventional exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cervical Disc Herniation
SYNCHRONOUS AND ASYNCHRONOUS TELEREHABILITATION METHODS IN PATIENTS WITH CERVICAL DISC HERNIATION
This was a randomized controlled trial conducted to examine the changes in the pain, physical function, quality of life, and kinesiophobia of participants with non-specific neck pain in Marmara University Physiotherapy and…
- Trial name
- NCT05501184
- Testing
- Synchronous Exercise Program, Asynchronous Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Biomechanical; Lesion
INVESTIGATING THE EFFECTS SACROILIAC JOINT DYSFUNCTION ON GAIT IN INDIVIDUALS WITH BACK PAIN
Sacroiliac joint dysfunction (SJD) is a common problem in individuals with lumbar herniation nucleus pulposus (LHNP) plus back pain.
- Trial name
- NCT03426852
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University