Clinical trials: Herniation, Disc
Lumbar Disc Prolapse With Radiculopathy
Safety Study of ARO Spinal System as an Adjunct to Lumbar Decompression
To evaluate the clinical safety and effectiveness of the ARO Spinal System and to assess preliminary cost/benefit analysis in patients undergoing decompression surgery for symptomatic lumbar disc herniations.
- Trial name
- NCT01970514
- Testing
- ARO Spinal System
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- ARO Medical
Herniated Disc
Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy
Summary: This is a prospective randomize study to compare conservative and aggressive discectomy for treatment of disc herniation with radiculopathy.
- Trial name
- NCT01204008
- Testing
- conservative discectomy, aggressive discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Diskectomy, Intervertebral Disk Displacement
Cervical Spine; Movement Before and After Anterior Cervical Discectomy, With or Without a Cervical Disc Prosthesis
The purpose of this study is to find out if use of a cervical disc prosthesis in the treatment of a cervical disc herniation preserves or restores normal mobility and movement in the cervical spine.
- Trial name
- NCT00868335
- Testing
- Activ C disc prosthesis, Anterior cervical discectomy
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Lumbal Disc Herniation
A Study Comparing Peloid Therapy and Hot Pack Treatment in Adults With Chronic Low Back Pain Caused by Lumbar Disc Herniation
The goal of this clinical trial is to compare the effectiveness of peloid therapy versus hot pack therapy in adults aged 18-50 with chronic lumbar disc herniation (LDH).
- Trial name
- NCT07087548
- Testing
- Peloid Therapy, Hotpack Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fenerbahce University
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Dorsal Root Ganglion Intervention Treatments
This study applies 3D-printed customized guide plate in assisting the accurate puncture in transforaminal epidural steroid injection (TFESI) combined with pulsed radiofrequency (PRF) treatment.
- Trial name
- NCT05403775
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation, Low Back Pain
Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery
This randomized controlled trial aims to compare the effectiveness of early mobilization alone versus early mobilization combined with electrical stimulation on functional recovery following lumbar disc herniation surgery.
- Conditions
- Lumbar Disc Herniation, Low Back Pain, Postoperative Rehabilitation
- Trial name
- EMES-LDH (NCT07575477)
- Testing
- Early Mobilization Program, Electrical Stimulation (NMES/TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Intervertebral Disc Displacement, Lumbar Disc Herniation
The Effect of Manual Therapy on Psychological Factors and Quality of Life in Lumbal Disc Herniation Patients
When the literature is examined, there are studies examining the relationship between low back pain and anxiety depression, quality of life and LDH in patients with lumbar disc herniation.
- Conditions
- Intervertebral Disc Displacement, Lumbar Disc Herniation, Psychological, Quality of Life
- Trial name
- NCT05804357
- Testing
- Manual Therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Lumbar Disc Herniation
PMCFU of an Annular Closure System
The purpose of this retrospective chart review study is to collect the data that will be used to provide clinical evidence to support the post-market surveillance program.
- Trial name
- NCT05467072
- Testing
- Annular closure
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Intrinsic Therapeutics
Cervical Disc Herniation, Cervical Spinal Stenosis
Edge Computing Platform for Spine Health Risk Management Based on IoT Technology
This project proposes to monitor the spinal posture of a person at rest and in motion in real time through a sensor device that contains spinal health monitoring as its core.
- Conditions
- Cervical Disc Herniation, Cervical Spinal Stenosis, Ossification of Posterior Longitudinal Ligament, Neckbrace Device
- Trial name
- NCT06092138
- Testing
- Wearable Device
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Cervical Stenosis, Disk, Herniated
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we…
- Conditions
- Cervical Stenosis, Disk, Herniated, Spondylosis
- Trial name
- NCT05356286
- Testing
- epidural electrical stimulation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Erector Spina Plan Block, Opioid Consumption
Effects of Erector Spinae Plane Block on Opioid Consumption, Anesthetic Consumption and Hemodynamics in Lumbar Disc Herniation Surgeries.
Lumbar disc herniation (LDH) is an increasingly common spine disorder . In patients treated surgically, inhalation anesthesia and the use of opioids for analgesic purposes are generally the chosen anesthetic methods.
- Conditions
- Erector Spina Plan Block, Opioid Consumption, Postoperative Pain
- Trial name
- NCT06933498
- Testing
- PREOPERATIVE ESPB, INTRAOPERATIVE ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Postoperative Pain, Shoulder Pain
Regional Analgesia for Anterior Cervical Disc and Fusion Surgery
Erector Spina Plane (ESP) block has been widely used in recent years, and it is also used in the control of postoperative analgesia in many types of surgery due to its proximity to the central area and its wide spread feature.
- Conditions
- Postoperative Pain, Shoulder Pain, Anesthesia, Local, Disc Herniation
- Trial name
- NCT05680142
- Testing
- superficial cervical plexus block, cervical erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Lumbar Disc Herniation
Percutaneous Endoscopic Lumbar Discectomy Add by Annuloplasty and Nucleoplasty
Recently, percutaneous endoscopic lumbar discectomy (PELD) is also commonly performed for lumbar disc herniation. Following discectomy, the relief of leg pain is common; however, the relief of back pain is less predictable.
- Trial name
- NCT05584774
- Testing
- PELDAN
- Volunteers
- 36 people
- Sponsor
- Ramathibodi Hospital
Lumbar Disc Herniation
Percutaneous Discectomy to Treat Symptomatic Lumbar Disc Herniation : Evaluation of Clinical Efficiency, Patient Reported Outcomes and Economical Impact by Assessing Time Before Return to Work and Duration of Hospitalization Stay
This study aims to evaluate the clinical (pain) and functional (patient reported outcomes) efficacy of percutaneous discectomies under CT guidance to treat lumbar disc herniations resistant to conservative treatment and nerve…
- Trial name
- NCT05772143
- Testing
- Percutaneous discectomies under CT
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cervical Disc Herniation, Cervical Radicular Pain
Does the Presence of Cervical Facet Tropism Affect the Response to Interlaminar Epidural Steroid Injections?
Facet joints are synovial joints located on the dorsolateral side of the vertebral column. Normally, both facet joints are symmetrical.
- Conditions
- Cervical Disc Herniation, Cervical Radicular Pain, Facet Tropism
- Trial name
- NCT05638074
- Testing
- Interlaminar Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Janbubi Jandaulyet
Lumbar Herniated Intervertebral Disc
The Efficacy and Safety of the 1,414 nm Nd:YAG Laser System for Alleviating Back Pain in a Lumbar Disc Patient
This study aims to evaluate the efficacy and safety of the 1,414nm Nd:YAG laser system (ACCUPLASTI) added to Percutaneous Epidural Neuroplasty (PEN), a conventional treatment, to alleviate back pain in a lumbar herniated…
- Trial name
- NCT02598232
- Testing
- 1,414nm Nd:YAG Laser System
- Volunteers
- 30 people
- Sponsor
- CynosureLutronic
Lumbar Disc Herniation With Radiculopathy, Low Back Pain (LBP)
"Effectiveness of Physical Therapy Added to Transforaminal Injection in Lumbar Radicular Pain"
The purpose of this study is to investigate whether adding conventional physical therapy modalities to transforaminal epidural steroid injection (TFESE) provides additional benefits in patients with acute radicular pain due to…
- Trial name
- NCT07467421
- Testing
- TFESE, TFESE+ CONVENTIONAL PHYSIOTHERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Lumbar Disc Herniation, Radiculopathy Lumbar
Comparison of the Effectiveness of Erector Spina Plane Block and Transforaminal Anterior Epidural Injections
Low back pain is one of the leading causes of disability and its social burden and economic cost are quite high. The lifetime prevalence in the population is frequently reported between 40% and 70%.
- Trial name
- NCT05719792
- Testing
- Transforaminal Epidural Steroid Injection, Erector Spina Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Herniated Disc, Intervertebral Disc Displacement
Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
The hypothesis of this study is that Gabapentin or Amitriptyline has no role in preemptive analgesia to reduce postoperative pain after lumbar diskectomies.
- Trial name
- NCT01014520
- Testing
- Gabapentin , Amitriptyline
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Tabriz University