Clinical trials: Herniation, Disc
Lumbar Herniated Disc
Ozone Therapy in Patients on Waiting List for Surgery Due to Disc Herniation: Prospective, Post-authorization Study
The main objective of this study is to estimate the cost-effectiveness of ozone therapy in patients on the waiting list for surgery due to disc herniation.
- Trial name
- O3HDCIRUGIA (NCT03282695)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Bernardino Clavo, MD, PhD
Cervical Disc Disease, Cervical Disc Herniation
Dynamic Cervical Implant in Treatment of Cervical Disc Disease
Evaluation of outcome of DCI in treatment of cervical disc disease to patients admitted to neurosurgery department, Asyut University Hospitals.
- Conditions
- Cervical Disc Disease, Cervical Disc Herniation, Cervical Disc Degeneration
- Trial name
- DCI (NCT04627454)
- Testing
- Discectomy and insertion of dynamic cervical implant in cervical disc herniation
- Volunteers
- 20 people
- Sponsor
- Assiut University
Surgical Site Infections, Lumbar Disc Herniation
The Effect of Number of Showers With 4% Chlorhexidine Gluconate on Prevention of Surgical Site Infections
Surgical site infections (SSIs) are the most common type of nosocomial infection in surgical departments. Although lumbar disc herniation (LDH), which is one of the common cases in neurosurgery, is a serious problem affecting…
- Trial name
- SSI (NCT06801275)
- Testing
- 1 shower with 4% chlorhexidine gluconate, 2 shower with 4% chlorhexidine gluconate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Lumbar Disc Herniation
A Study to Evaluate Safety and Exploratory Efficacy of KTP-001 in Subjects With Lumbar Disc Herniation
The purpose of this study is to evaluate the safety and exploratory efficacy of KTP-001 in subjects with lumbar disc herniation.
- Trial name
- NCT01978912
- Testing
- KTP-001
- Where
- 10 sites in United States
- Volunteers
- 24 people
- Sponsor
- Teijin America, Inc.
Cervical Vertebral Disc Degeneration, Intervertebral Disc Displacement
Cervical Movement Control Before and After Anterior Cervical Discectomy and Fusion
Degenerative cervical disc disease can cause neck pain, nerve symptoms, dizziness, and problems with balance and head movement control.
- Trial name
- MOVE-ACDF (NCT07425613)
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University of Ljubljana
Lumbal Disc Herniation, Capacitive and Resistive Electric Transfer Therapy
Tecar Therapy in Lumbar Disc Herniation
This randomized controlled trial investigates the effects of Tecar therapy on pain intensity and functional status in patients with lumbar disc herniation.
- Conditions
- Lumbal Disc Herniation, Capacitive and Resistive Electric Transfer Therapy, Exercise Training
- Trial name
- LDH-TECAR (NCT07082660)
- Testing
- High-Frequency Capacitive-Resistive Diathermic Current Therapy (TECAR), Lumbal Stabilization Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Şebnem Nur Alkan
Instrument-assisted Soft Tissue Mobilization, Treatment
Investigation of The Effect of "Instrument-Assisted Soft Tissue Mobilization" in Individuals With Lumbar Disc Herniation
Instrument-assisted soft tissue mobilization is an instrument-assisted soft tissue mobilization technique. It consists of stainless steel instrument designed to adapt to various tissues/shapes/curves of the body.
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Treatment, Exercise, Pain
- Trial name
- NCT06529926
- Testing
- Observational, IASTM Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Degenerative Spinal Stenosis, Disk Herniation
Clinical Trial to Evaluate Safety and Efficacy of Hyalospine® in Lumbar Laminectomy or Laminotomy
The aim of this Phase II trial is to evaluate safety and efficacy of Hyalospine in patients undergoing lumbar laminectomy or laminotomy for degenerative spinal stenosis or disk herniation.
- Trial name
- Hyalospine (NCT00939406)
- Testing
- Hyalospine
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 45 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Lumbar Disc Herniation Surgery, Mechanical Ventilation
Flow-Controlled Versus Volume-Controlled Ventilation in Lumbar Disc Herniation Surgery
This prospective randomized trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in patients undergoing lumbar disc…
- Trial name
- NCT07614555
- Testing
- FCV Group, VCV Group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Thoracic Disc Herniation
The Incidence of Thoracic Disc Herniation in Patients Presenting With Chronic Upper Back Pain
Patients who applied to the Private Medar Hospital between February 2016 and February 2021 with chronic upper back pain and were diagnosed with Thoaracic Disc Herniatin (TDH) (with Thoracic vertebral MRI) and followed up for at…
- Trial name
- NCT05313997
- Testing
- Diclofenac Sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people
- Sponsor
- Kocaeli University
Lumbar Disc Herniation, Protrusion
Lumbar Kinematics in People With the Low Back Pain
This study evaluates the effect of lumbar disc herniation on kinematics in the lumbopelvic region during daily living activities.
- Conditions
- Lumbar Disc Herniation, Protrusion, Extrusion of Migrated Disc, Hernia
- Trial name
- NCT04417855
- Testing
- G-Walk
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Lumbar Vertebra Hernia
SI-6603 Versus Placebo in Patients With Lumbar Disc Herniation
The purpose of this study is to determine whether SI-6603 is effective in the treatment of lumbar disc herniation.
- Trial name
- NCT00634946
- Testing
- SI-6603
- Where
- 8 sites in Japan
- Volunteers
- 195 people
- Sponsor
- Seikagaku Corporation
Lumbar Disc Herniation, Radiculopathy Lumbar
The Effect of Subcutaneous Fat Tissue Thickness on Lumbar Transforaminal Epidural Steroid Injection Treatment Success
Nerve compression due to lumbar disc herniation and related radicular pain is a very common condition when the lifetime prevalence is considered.
- Conditions
- Lumbar Disc Herniation, Radiculopathy Lumbar, Obesity
- Trial name
- NCT05556538
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Marmara University
Lumbar Radiculopathy, Lumbar Disc Herniation
Randomized Evaluation of Lumbar Injection Effectiveness and Function
The goal of this clinical trial is to learn whether the Triojection® System is safe and effective for treating symptomatic lumbar radiculopathy (leg pain caused by nerve irritation or compression) resulting from a contained…
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Contained Herniated Lumbar Disc
- Trial name
- RELIEF (NCT07856810)
- Testing
- Triojection® System, Selective Nerve Root Block (SNRB)
- Volunteers
- 300 people
- Sponsor
- SpinaFX Medical Inc.
VAS and JOA Scores, Adverse Reaction Rates
Combined Therapy for Cervical Disc Herniation
This study mainly explores the efficacy and safety of low-temperature plasma radiofrequency ablation combined with ozone injection and collagenase in the treatment of cervical disc herniation.The primary outcomes included the…
- Conditions
- VAS and JOA Scores, Adverse Reaction Rates, Clinical Efficacy at 1 Month and 6 Months
- Trial name
- NCT06995066
- Testing
- collagenase injection into the epidural space
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanchong Central Hospital
Low Back Pain, Neck Pain
Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders
The primary objective is to use machine learning methods on large survey and health register data to identify participants with different treatment trajectories and health outcomes after surgical and/or conservative treatment for…
- Conditions
- Low Back Pain, Neck Pain, Disc Herniation, Disc Degeneration
- Trial name
- AID-Spine (NCT05745129)
- Where
- Norway
- Volunteers
- 165,000 people
- Sponsor
- Oslo Metropolitan University
Disc Herniation
Caudal Neuroplasty Using Epidural Catheter Combined with Pulsed Radiofrequency (versus Pulsed Radiofrequency Alone
Evaluating the superiority of caudal neuroplasty using epidural catheter (Perifix® Complete Set 16 G) combined with Pulsed Radiofrequency (PRF) versus Pulsed Radiofrequency (PRF) alone targeting the dorsal root ganglion In…
- Trial name
- NCT06711419
- Testing
- f caudal neuroplasty using epidural catheter combined with Pulsed Radiofrequency (PRF) versus Pulsed Radiofrequency (PRF) alone
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Disc Herniation, Surgery
Exercise After Lumbar Disc Herniation Surgery
Physical therapy and rehabilitation may improve low back pain and quality of life after lumbar disc herniation. But there is not any agreement of its optimal start time, and rehabilitative methods.
- Trial name
- NCT06046781
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul Medeniyet University
Lumbar Disc Herniation, Degenerative Disc Disease
Peri-Incisional Drug Injection in Lumbar Spine Surgery
This is a randomized prospective study that will compare the use of narcotics in a control group of non-injected patients with a treatment arm of patients injected intra-operatively with a ropivacaine, morphine, and epinephrine…
- Conditions
- Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
- Trial name
- NCT03513445
- Testing
- Morphine, Epinephrine, naropin
- Where
- United States
- Sponsor
- University of Minnesota
Lumbar Disc Herniation
Quadratus Lumborum Block for Lumbar Spinal Surgery
Spine surgery in thoracolumbar region is one of the most common surgeries performed for the treatment of leg and back pain. Pain management is especially important for these patients since chronic pain often occurs after surgery.
- Trial name
- NCT04981301
- Testing
- Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University